Publications by authors named "Linus Johannissen"

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Structural basis of terephthalate recognition by solute binding protein TphC.
Trishnamoni Gautom, Dharmendra Dheeman, Colin Levy, Thomas Butterfield, Guadalupe Alvarez Gonzalez, Philip Le Roy, Lewis Caiger, Karl Fisher, Linus Johannissen, Neil Dixon

October 2021

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Expanding the substrate scope of a bacterial monoterpene synthase for the production of sesquiterpenoid and diterpenoid products.
Nicole G H Leferink, Joshua N Whitehead, Linus O Johannissen, Nigel S Scrutton

FEBS J· October 2025

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Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2 + 2]-Cycloadditions.
Chuanjie Sun, Anna R Kohn, Ross Smithson, Florence J Hardy, Jonathan S Trimble, Linus O Johannissen

Angew Chem Int Ed Engl· August 2025

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Conformational Sampling during the Reaction of the SARS-CoV-2 Methyltransferase nsp16.
Yuanxin Cao, James D Green, Linus O Johannissen, Sam Hay

J Phys Chem B· August 2025

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Engineered enzymes for enantioselective nucleophilic aromatic substitutions.
Thomas M Lister, George W Roberts, Euan J Hossack, Fei Zhao, Ashleigh J Burke, Linus O Johannissen

Nature· March 2025

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A Machine Learning Model for the Prediction of Water Contact Angles on Solid Polymers.
Jose Sena, Linus O Johannissen, Jonny J Blaker, Sam Hay

J Phys Chem B· March 2025

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SignatureFinder enables sequence mining to identify cobalamin-dependent photoreceptor proteins.
Yuqi Yu, Laura N Jeffreys, Harshwardhan Poddar, Adam Hill, Linus Johannissen

FEBS J· February 2025

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Directed Evolution's Selective Use of Quantum Tunneling in Designed Enzymes─A Combined Theoretical and Experimental Study.
Kseniia Korchagina, Sree Ganesh Balasubramani, Jordan Berreur, Emilie F Gerard, Linus O Johannissen

J Phys Chem B· February 2025

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Mechanistic implications of the ternary complex structural models for the photoenzyme protochlorophyllide oxidoreductase.
Aoife Taylor, Shaowei Zhang, Linus O Johannissen, Michiyo Sakuma, Robert S Phillips

FEBS J· April 2024

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A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme.
Amy E Hutton, Jake Foster, Rebecca Crawshaw, Florence J Hardy, Linus O Johannissen

Nat Commun· March 2024

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Photocobilins integrate B and bilin photochemistry for enzyme control.
Shaowei Zhang, Laura N Jeffreys, Harshwardhan Poddar, Yuqi Yu, Chuanyang Liu, Linus O Johannissen

Nat Commun· March 2024

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Decoding Catalysis by Terpene Synthases.
Joshua N Whitehead, Nicole G H Leferink, Linus O Johannissen, Sam Hay, Nigel S Scrutton

ACS Catal· October 2023

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Redox driven B-ligand switch drives CarH photoresponse.
Harshwardhan Poddar, Ronald Rios-Santacruz, Derren J Heyes, Muralidharan Shanmugam, Adam Brookfield, Linus O Johannissen

Nat Commun· August 2023

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How Is Substrate Halogenation Triggered by the Vanadium Haloperoxidase from ?
Emilie F Gérard, Thirakorn Mokkawes, Linus O Johannissen, Jim Warwicker, Reynard R Spiess

ACS Catal· June 2023

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Photoinduced Electron Transfer from a 1,4,5,6-Tetrahydro Nicotinamide Adenine Dinucleotide (Phosphate) Analogue to Oxidized Flavin in an Ene-Reductase Flavoenzyme.
Magnus Speirs, Samantha J O Hardman, Andreea I Iorgu, Linus O Johannissen, Derren J Heyes

J Phys Chem Lett· April 2023

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A Vitamin B -Photocatalysed Approach to Methionine Analogues.
Oliver J Knowles, Linus O Johannissen, Giacomo E M Crisenza, Sam Hay, David Leys

Angew Chem Int Ed Engl· December 2022

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A Vitamin B-Photocatalysed Approach to Methionine Analogues.
Oliver J Knowles, Linus O Johannissen, Giacomo E M Crisenza, Sam Hay, David Leys

Angew Chem Weinheim Bergstr Ger· December 2022

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Mechanism of Action of Flavin-Dependent Halogenases.
Rhys D Barker, Yuqi Yu, Leonardo De Maria, Linus O Johannissen, Nigel S Scrutton

ACS Catal· December 2022

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Chelator-Based Parameterization of the 12-6-4 Lennard-Jones Molecular Mechanics Potential for More Realistic Metal Ion-Protein Interactions.
Paulius Kantakevičius, Calvin Mathiah, Linus O Johannissen, Sam Hay

J Chem Theory Comput· April 2022

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How Photoactivation Triggers Protochlorophyllide Reduction: Computational Evidence of a Stepwise Hydride Transfer during Chlorophyll Biosynthesis.
Linus O Johannissen, Aoife Taylor, Samantha J O Hardman, Derren J Heyes, Nigel S Scrutton

ACS Catal· April 2022

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Engineering an efficient and enantioselective enzyme for the Morita-Baylis-Hillman reaction.
Rebecca Crawshaw, Amy E Crossley, Linus Johannissen, Ashleigh J Burke, Sam Hay

Nat Chem· March 2022

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Publisher Correction: Photocatalysis as the 'master switch' of photomorphogenesis in early plant development.
Derren J Heyes, Shaowei Zhang, Aoife Taylor, Linus O Johannissen, Samantha J O Hardman

Nat Plants· May 2021

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Interplay between chromophore binding and domain assembly by the B-dependent photoreceptor protein, CarH.
Inês S Camacho, Rachelle Black, Derren J Heyes, Linus O Johannissen, Lennart A I Ramakers

Chem Sci· May 2021

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Photocatalysis as the 'master switch' of photomorphogenesis in early plant development.
Derren J Heyes, Shaowei Zhang, Aoife Taylor, Linus O Johannissen, Samantha J O Hardman

Nat Plants· March 2021

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Predicting new protein conformations from molecular dynamics simulation conformational landscapes and machine learning.
Yiming Jin, Linus O Johannissen, Sam Hay

Proteins· February 2021

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