Publications by authors named "LongLong Si"

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A scalable human liver-on-a-chip platform for predictive safety assessment.
Gauri Kulkarni, Lizao Chen, Jing Sang, Ji Hye Seo, Romain Grall, Hardeep Singh, Longlong Si

Toxicology· December 2025

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Inflammation and epithelial-mesenchymal transition in a CFTR-depleted human bronchial epithelial cell line revealed by proteomics and human organ-on-a-chip.
Domenico Mattoscio, Luis A Baeza, Haiqing Bai, Tommaso Colangelo, Simone Castagnozzi, Longlong Si, Simona D'Orazio

FEBS J· October 2025

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PROTAR Vaccine 2.0 generates influenza vaccines by degrading multiple viral proteins.
Chunhe Zhang, Jihuan Hou, Zhen Li, Quan Shen, Haiqing Bai, Qisi Zhang, Longlong Si

Nat Chem Biol· September 2025

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Author Correction: PROTAR Vaccine 2.0 generates influenza vaccines by degrading multiple viral proteins.
Chunhe Zhang, Jihuan Hou, Zhen Li, Quan Shen, Haiqing Bai, Qisi Zhang, Longlong Si

Nat Chem Biol· September 2025

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Live vaccine development through targeted protein degradation.
Qisi Zhang, Longlong Si

Nat Rev Immunol· September 2025

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Author Correction: Proteolysis-targeting influenza vaccine strains induce broad-spectrum immunity and in vivo protection.
Jinying Shen, Jing Li, Quan Shen, Jihuan Hou, Chunhe Zhang, Qisi Zhang, Longlong Si

Nat Microbiol· August 2025

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Synthetic biology-inspired development of live attenuated influenza vaccines.
Qisi Zhang, Jiahui Cheng, Jihuan Hou, Yinlei Su, Le Li, Longlong Si

NPJ Vaccines· August 2025

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DNA origami vaccine (DoriVac) nanoparticles improve both humoral and cellular immune responses to infectious diseases.
Yang C Zeng, Olivia J Young, Qiancheng Xiong, Longlong Si, Min Wen Ku, Giorgia Isinelli, Chris M Wintersinger

bioRxiv· April 2025

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Engineering extracellular vesicles derived from endothelial cells sheared by laminar flow for anti-atherosclerotic therapy through reprogramming macrophage.
Chunli Li, Fei Fang, Erxiang Wang, Hanqiao Yang, Xinrui Yang, Longlong Si

Biomaterials· March 2025

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Host Serine Proteases and Antiviral Innate Immunity as Potential Therapeutic Targets in Influenza A Virus Infection-Induced COPD Exacerbations.
Haiqing Bai, Melissa Rodas, Longlong Si, Yuncheng Man, Jie Ji

Int J Mol Sci· March 2025

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Natural Infection of Omicron BA.5.2 in Patients Provides Broad Immune Responses Against SARS-CoV-2.
Le Li, Tang Feng, Quan Shen, Xiaoshan Shi, Zhigong Wei, Qisi Zhang, Longlong Si

Microorganisms· March 2025

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Proteolysis-targeting influenza vaccine strains induce broad-spectrum immunity and in vivo protection.
Jinying Shen, Jing Li, Quan Shen, Jihuan Hou, Chunhe Zhang, Qisi Zhang, Longlong Si

Nat Microbiol· February 2025

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Cross-species recognition of two porcine coronaviruses to their cellular receptor aminopeptidase N of dogs and seven other species.
Yuyang Tian, Junqing Sun, Xiaohan Hou, Zhimin Liu, Zeao Chen, Longlong Si

PLoS Pathog· January 2025

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A Subunit Vaccine Harboring the Fusion Capsid Proteins of Porcine Circovirus Types 2, 3, and 4 Induces Protective Immune Responses in a Mouse Model.
Qikai Wang, Ran Zhang, Yue Wang, Ying Wang, Libin Liang, Longlong Si

Viruses· December 2024

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Electrohydrodynamic Direct-Writing Micro/Nanofibrous Architectures: Principle, Materials, and Biomedical Applications.
Zhengjiang Liu, Jinqiao Jia, Qi Lei, Yan Wei, Yinchun Hu, Longlong Si

Adv Healthc Mater· November 2024

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Patient-derived organoids in precision cancer medicine.
Le Tong, Weiyingqi Cui, Boya Zhang, Pedro Fonseca, Qian Zhao, Qisi Zhang, Longlong Si

Med· November 2024

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Rapid Prototyping of Thermoplastic Microfluidic 3D Cell Culture Devices by Creating Regional Hydrophilicity Discrepancy.
Haiqing Bai, Kristen N Peters Olson, Ming Pan, Thomas Marshall, Hardeep Singh, Longlong Si

Adv Sci (Weinh)· February 2024

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Optimization and applications of an in vivo bioluminescence imaging model of influenza A virus infections.
Xiaojing Lin, Murong Zhu, Xiujuan Zhao, Longlong Si, Meiyue Dong

Virol Sin· August 2023

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PROTAC vaccine: A new way to live attenuated vaccines.
Zhen Li, Haiqing Bai, Xuetong Xi, Wen-Xia Tian, John Z H Zhang, Longlong Si

Clin Transl Med· October 2022

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Generation of a live attenuated influenza A vaccine by proteolysis targeting.
Longlong Si, Quan Shen, Jing Li, Li Chen, Jinying Shen, Siwen Niu

Nat Biotechnol· September 2022

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Self-assembling short immunostimulatory duplex RNAs with broad-spectrum antiviral activity.
Longlong Si, Haiqing Bai, Crystal Yuri Oh, Amanda Jiang, Fan Hong

Mol Ther Nucleic Acids· September 2022

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3D Lung Tissue Models for Studies on SARS-CoV-2 Pathophysiology and Therapeutics.
Roberto Plebani, Haiqing Bai, Longlong Si, Jing Li, Chunhe Zhang

Int J Mol Sci· September 2022

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SNTA1-deficient human cardiomyocytes demonstrate hypertrophic phenotype and calcium handling disorder.
Tao Dong, Yan Zhao, Hai-Feng Jin, Lei Shen, Yan Lin, Long-Long Si

Stem Cell Res Ther· June 2022

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Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip.
Haiqing Bai, Longlong Si, Amanda Jiang, Chaitra Belgur, Yunhao Zhai

Nat Commun· April 2022

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Self-assembling short immunostimulatory duplex RNAs with broad spectrum antiviral activity.
Longlong Si, Haiqing Bai, Crystal Yuri Oh, Tian Zhang, Fan Hong

bioRxiv· November 2021

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