Publications by authors named "LuZhe Sun"

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Structural and spectroscopic resolution of the NADPH redox state in the STEAP2 cytosolic oxidoreductase domain.
Inchul Shin, Lu-Zhe Sun, Aimin Liu

J Biol Chem· December 2025

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A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice.
Yang Yang, Natacha Jn-Simon, Yonghan He, Chunbao Sun, Peiyi Zhang, Lu-Zhe Sun

Nat Aging· March 2025

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Integrative multi-omics characterization of hepatocellular carcinoma in Hispanic patients.
Debodipta Das, Xiaojing Wang, Yu-Chiao Chiu, Hakim Bouamar, Francis E Sharkey, Lu-Zhe Sun

J Natl Cancer Inst· December 2024

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Ficolin-3 induces apoptosis and suppresses malignant property of hepatocellular carcinoma cells via the complement pathway.
Guixi Zheng, Lianqiu Wu, Hakim Bouamar, Matyas Cserhati, Yu-Chiao Chiu, Lu-Zhe Sun

Life Sci· November 2024

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PELP1 Is a Novel Therapeutic Target in Hepatocellular Carcinoma.
Khaled Mohamed Nassar, Xue Yang, Adriana Baker, Rahul Gopalam, William C Arnold, Lu-Zhe Sun

Cancer Res Commun· October 2024

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Antibody-activation of connexin hemichannels in bone osteocytes with ATP release suppresses breast cancer and osteosarcoma malignancy.
Manuel A Riquelme, Xuewei Wang, Francisca M Acosta, Jingruo Zhang, Jeffery Chavez, Lu-Zhe Sun

Cell Rep· July 2024

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STEAP2 promotes hepatocellular carcinoma progression via increased copper levels and stress-activated MAP kinase activity.
Carla Zeballos Torrez, Acarizia Easley, Hakim Bouamar, Guixi Zheng, Xiang Gu, Lu-Zhe Sun

Sci Rep· June 2024

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Integrative multi-omics characterization of hepatocellular carcinoma in Hispanic patients.
Debodipta Das, Xiaojing Wang, Yu-Chiao Chiu, Hakim Bouamar, Francis E Sharkey, Lu-Zhe Sun

medRxiv· April 2024

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Reconstitution of human PDAC using primary cells reveals oncogenic transcriptomic features at tumor onset.
Yi Xu, Michael H Nipper, Angel A Dominguez, Zhenqing Ye, Naoki Akanuma, Lu-Zhe Sun

Nat Commun· January 2024

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mTOR inhibition abrogates human mammary stem cells and early breast cancer progression markers.
Hakim Bouamar, Larry Esteban Broome, Kate Ida Lathrop, Ismail Jatoi, Andrew Jacob Brenner, Lu-Zhe Sun

Breast Cancer Res· October 2023

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Upregulated TGF-β1 contributes to hyperglycaemia in type 2 diabetes by potentiating glucagon signalling.
Yang Xiao, Yanfei Wang, Jiyoon Ryu, Wei Liu, Hailan Zou, Lu-Zhe Sun

Diabetologia· June 2023

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Integrin alpha 6 is upregulated and drives hepatocellular carcinoma progression through integrin α6β4 complex.
Guixi Zheng, Hakim Bouamar, Matyas Cserhati, Carla R Zeballos, Isha Mehta, Lu-Zhe Sun

Int J Cancer· September 2022

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Fbxo22 promotes cervical cancer progression via targeting p57 for ubiquitination and degradation.
Min Lin, Jianan Zhang, Hakim Bouamar, Zhiwei Wang, Lu-Zhe Sun

Cell Death Dis· September 2022

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Association of adenosine signaling gene signature with estrogen receptor-positive breast and prostate cancer bone metastasis.
Daniel Brian Shropshire, Francisca M Acosta, Kun Fang, Jaime Benavides, Lu-Zhe Sun

Front Med (Lausanne)· September 2022

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GLI3 and androgen receptor are mutually dependent for their malignancy-promoting activity in ovarian and breast cancer cells.
Min Lin, Haiyan Zhu, Qi Shen, Lu-Zhe Sun, Xueqiong Zhu

Cell Signal· April 2022

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GLI3 Is Stabilized by SPOP Mutations and Promotes Castration Resistance via Functional Cooperation with Androgen Receptor in Prostate Cancer.
Marieke Burleson, Janice J Deng, Tai Qin, Thu Minh Duong, Yuqian Yan, Lu-Zhe Sun

Mol Cancer Res· January 2022

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Osteocytic Connexin Hemichannels Modulate Oxidative Bone Microenvironment and Breast Cancer Growth.
Yi Tian, Manuel A Riquelme, Chao Tu, Yumeng Quan, Xiaowen Liu, Lu-Zhe Sun

Cancers (Basel)· December 2021

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Gli2 mediates the development of castration‑resistant prostate cancer.
Lu Xia, Hakim Bouamar, Xiang Gu, Carla Zeballos, Tai Qin, Lu-Zhe Sun

Int J Oncol· July 2020

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Age-associated genes in human mammary gland drive human breast cancer progression.
Xiang Gu, Bingzhi Wang, Haiyan Zhu, You Zhou, Aaron M Horning, Lu-Zhe Sun

Breast Cancer Res· June 2020

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Mifepristone inhibits IGF-1 signaling pathway in the treatment of uterine leiomyomas.
Qi Shen, Shuangwei Zou, Bo Sheng, Menghuang Zhao, Lu-Zhe Sun

Drug Des Devel Ther· April 2020

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Everolimus Inhibits the Progression of Ductal Carcinoma to Invasive Breast Cancer Via Downregulation of MMP9 Expression.
Guang Chen, Xiao-Fei Ding, Kyle Pressley, Hakim Bouamar, Bingzhi Wang, Lu-Zhe Sun

Clin Cancer Res· March 2020

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Prostate Cancer Epithelial Mesenchymal Transition by TGF-β1 exposure monitored with a Photonic Crystal Biosensor.
Melissa Cadena, Frank DeLuna, Kwaku Baryeh, Lu-Zhe Sun, Jing Yong Ye

Proc SPIE Int Soc Opt Eng· February 2020

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An ancestry informative marker panel design for individual ancestry estimation of Hispanic population using whole exome sequencing data.
Li-Ju Wang, Catherine W Zhang, Sophia C Su, Hung-I H Chen, Yu-Chiao Chiu, Lu-Zhe Sun

BMC Genomics· December 2019

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Everolimus induces G cell cycle arrest through autophagy-mediated protein degradation of cyclin D1 in breast cancer cells.
Guang Chen, Xiao-Fei Ding, Hakim Bouamar, Kyle Pressley, Lu-Zhe Sun

Am J Physiol Cell Physiol· August 2019

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Effects of dynein light chain Tctex-type 3 on the biological behavior of ovarian cancer.
Lulu Zhou, Miaomiao Ye, Fang Xue, Ermei Lu, Lu-Zhe Sun

Cancer Manag Res· July 2019

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