Publications by authors named "Lutz Achtnichts"

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Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis.
Stephanie Meier, Eline A J Willemse, Sabine Schaedelin, Johanna Oechtering, Johannes Lorscheider, Lester Melie-Garcia, Alessandro Cagol, Muhamed Barakovic, Riccardo Galbusera, Suvitha Subramaniam

JAMA Neurol· March 2023

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Biomarker discovery using NUcleic Acid-Linked Immuno-Sandwich Assay in multiple sclerosis patients experiencing progression independent of relapse activity.
Sofia Sandgren, Aleksandra Maleska Maceski, Pascal Benkert, Maximilian Einsiedler, Sabine Schaedelin, Lutz Achtnichts

Mult Scler· November 2025

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Blood biomarkers for predicting disability worsening in progressive multiple sclerosis: a multinational, individual participant-level analysis.
Ahmed Abdelhak, Franziska Bachhuber, Kiarra Ning, Pascal Benkert, W John Boscardin, Lutz Achtnichts

J Neurol Neurosurg Psychiatry· October 2025

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Treatment Strategies and Disease Activity During Pregnancy and Postpartum: Real-World Data From the Swiss Multiple Sclerosis Cohort.
Maximilian Einsiedler, Chiara Zecca, Lisa Hofer, Pascal Benkert, Cathrine Axfors, Lutz Achtnichts

Neurol Clin Pract· August 2025

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Personalized treatment decision algorithms for the clinical application of serum neurofilament light chain in multiple sclerosis: A modified Delphi Study.
Özgür Yaldizli, Pascal Benkert, Lutz Achtnichts, Amit Bar-Or, Viviane Bohner-Lang

Mult Scler· July 2025

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Aberrant Complement Activation Is Associated With Structural Brain Damage in Multiple Sclerosis.
Johanna Oechtering, Sabine Anna Schaedelin, Kerstin Stein, Aleksandra Maleska Maceski, Lester Melie-Garcia, Lutz Achtnichts

Neurol Neuroimmunol Neuroinflamm· March 2025

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Treatment persistence and clinical outcomes in patients starting B cell depleting therapies within the Swiss MS Cohort.
Giulio Disanto, Sabine Schaedelin, Johanna Oechtering, Johannes Lorscheider, Riccardo Galbusera, Lutz Achtnichts

Mult Scler J Exp Transl Clin· February 2025

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Serum Glial Fibrillary Acidic Protein and Neurofilament Light Chain Levels Reflect Different Mechanisms of Disease Progression under B-Cell Depleting Treatment in Multiple Sclerosis.
Pascal Benkert, Aleksandra Maleska Maceski, Sabine Schaedelin, Johanna Oechtering, Amar Zadic, Lutz Achtnichts

Ann Neurol· October 2024

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MultiSCRIPT-Cycle 1-a pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions in multiple sclerosis: a study protocol for a randomized clinical trial.
Perrine Janiaud, Chiara Zecca, Anke Salmen, Pascal Benkert, Sabine Schädelin, Lutz Achtnichts

Trials· September 2024

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Complement Activation Is Associated With Disease Severity in Multiple Sclerosis.
Johanna Oechtering, Kerstin Stein, Sabine A Schaedelin, Aleksandra M Maceski, Annette Orleth, Lutz Achtnichts

Neurol Neuroimmunol Neuroinflamm· March 2024

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Association of Spinal Cord Atrophy and Brain Paramagnetic Rim Lesions With Progression Independent of Relapse Activity in People With MS.
Alessandro Cagol, Pascal Benkert, Lester Melie-Garcia, Sabine A Schaedelin, Selina Leber, Lutz Achtnichts

Neurology· January 2024

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Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis.
Ahmed Abdelhak, Pascal Benkert, Sabine Schaedelin, W John Boscardin, Christian Cordano, Lutz Achtnichts

JAMA Neurol· December 2023

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A Multicenter Longitudinal MRI Study Assessing LeMan-PV Software Accuracy in the Detection of White Matter Lesions in Multiple Sclerosis Patients.
Alexandra Ramona Todea, Lester Melie-Garcia, Muhamed Barakovic, Alessandro Cagol, Reza Rahmanzadeh, Lutz Achtnichts

J Magn Reson Imaging· September 2023

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Correlation of disability with quality of life in patients with multiple sclerosis treated with natalizumab: primary results and post hoc analysis of the TYSabri ImPROvement study (PROTYS).
Lutz Achtnichts, Chiara Zecca, Oliver Findling, Christian P Kamm, Stefanie Mueller

BMJ Neurol Open· January 2023

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Oral disease modifying therapies - A game changer for treatment decision in untreated patients with RRMS and CIS? - A swiss single center cross-sectional study.
Sebastian Finkener, Lutz Achtnichts, Michaela Cervenakova, Krassen Nedeltchev, Oliver Findling

Mult Scler Relat Disord· December 2022

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Association of Brain Atrophy With Disease Progression Independent of Relapse Activity in Patients With Relapsing Multiple Sclerosis.
Alessandro Cagol, Sabine Schaedelin, Muhamed Barakovic, Pascal Benkert, Ramona-Alexandra Todea, Lutz Achtnichts

JAMA Neurol· July 2022

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Intrathecal IgM Synthesis Is Associated with Spinal Cord Manifestation and Neuronal Injury in Early MS.
Johanna Oechtering, Therese Lincke, Sabine Schaedelin, Bernhard F Décard, Aleksandra Maceski, Lutz Achtnichts

Ann Neurol· June 2022

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Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study.
Pascal Benkert, Stephanie Meier, Sabine Schaedelin, Ali Manouchehrinia, Özgür Yaldizli, Lutz Achtnichts

Lancet Neurol· March 2022

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SARS-CoV-2 mRNA Vaccination in People with Multiple Sclerosis Treated with Fingolimod: Protective Humoral Immune Responses May Develop after the Preferred Third Shot.
Lutz Achtnichts, Arkady Ovchinnikov, Barbara Jakopp, Michael Oberle, Krassen Nedeltchev

Vaccines (Basel)· February 2022

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Humoral Immune Response after the Third SARS-CoV-2 mRNA Vaccination in CD20 Depleted People with Multiple Sclerosis.
Lutz Achtnichts, Barbara Jakopp, Michael Oberle, Krassen Nedeltchev, Christoph Andreas Fux

Vaccines (Basel)· December 2021

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Intrathecal Immunoglobulin M Synthesis is an Independent Biomarker for Higher Disease Activity and Severity in Multiple Sclerosis.
Johanna Oechtering, Sabine Schaedelin, Pascal Benkert, Stefanie Müller, Lutz Achtnichts

Ann Neurol· September 2021

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Role of Family Planning in Women With Multiple Sclerosis in Switzerland: Results of the Women With Multiple Sclerosis Patient Survey.
Christian P Kamm, Sarah Muehl, Dennis Mircsof, Stefanie Müller, Adam Czaplinski, Lutz Achtnichts

Front Neurol· October 2018

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Long-term evaluation of NEDA-3 status in relapsing-remitting multiple sclerosis patients after switching from natalizumab to fingolimod.
Lara Diem, Krassen Nedeltchev, Timo Kahles, Lutz Achtnichts, Oliver Findling

Ther Adv Neurol Disord· August 2018

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A comparison of balance control during stance and gait in patients with inflammatory and non-inflammatory polyneuropathy.
Oliver Findling, Rens van der Logt, Krassen Nedeltchev, Lutz Achtnichts, John H J Allum

PLoS One· March 2018

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The Swiss Multiple Sclerosis Cohort-Study (SMSC): A Prospective Swiss Wide Investigation of Key Phases in Disease Evolution and New Treatment Options.
Giulio Disanto, Pascal Benkert, Johannes Lorscheider, Stefanie Mueller, Jochen Vehoff, Lutz Achtnichts

PLoS One· August 2016

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