Publications by authors named "M C Nonato"

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Targeting dihydroorotate dehydrogenase (DHODH) for host-directed therapy: Discovery of a novel alkyne-based scaffold inhibitor effective against SARS-CoV-2.
Miguel M Vaidergorn, Aline D Purificação, Pedro I P Leite, Sabrina Silva-Mendonça, Wemenes J L Silva, M Cristina Nonato

Eur J Med Chem· November 2025

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Barbituric Acid Derivatives as Covalent Inhibitors of Dihydroorotate Dehydrogenase.
Thamires Quadros Froes, Temitayo Omowumi Alegbejo Price, Bruna Fleck Godoi, Miguel Menezes Vaidergorn, Thiago Dos Santos, Maria Cristina Nonato

J Med Chem· September 2025

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Hit-to-Lead Studies of Pyrazinylpiperazines against Visceral Leishmaniasis: Pharmacokinetic Profile and Efficacy of Potent Compounds against .
Thibault Joseph William Jacques Dit Lapierre, Mariza Gabriela Faleiro de Moura Lodi Cruz, Gisele Barbosa, Analu R Costa, Miguel Angel Chávez-Fumagalli, Maria Cristina Nonato

ACS Pharmacol Transl Sci· August 2025

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Crystallographic Structure of Human Dihydroorotate Dehydrogenase in Complex with the Natural Product Inhibitor Lapachol.
Aline D Purificação, Laila S Benz, Wemenes J Lima Silva, Flavio S Emery, Carolina Horta Andrade, Maria Cristina Nonato

ACS Omega· July 2025

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Synthesis and Biological Evaluation of 4‑(4-Nitrophenyl)‑1‑1,2,3-triazole Derivatives as Antitrypanosomal Agents.
Filipe Canto Oliveira, Luís Otávio Bunhotto Zamoner, Marcelo Dias Baruffi, Beatriz Silveira Augusto, Miguel de Menezes Vaidergorn, Maria Cristina Nonato

ACS Omega· May 2025

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