Publications by authors named "M Niedbala"

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Modeling response to the KRAS-G12C inhibitor AZD4625 in KRAS NSCLC patient-derived xenografts reveals insights into primary resistance mechanisms.
Joshua C Rosen, Pinjiang Cao, Nhu-An Pham, Matthew Waas, Quan Li, Michael Niedbala

Br J Cancer· January 2026

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Use of new approach methodology for hepatic safety assessment of covalent inhibitor drug candidates.
Sara Amberntsson, Alison J Foster, Bhavik Chouhan, Stephen Wilkinson, Stephanie Harlfinger, Michael Niedbala

Toxicol Res (Camb)· June 2025

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Molecular signature of primate astrocytes reveals pathways and regulatory changes contributing to human brain evolution.
Katarzyna Ciuba, Aleksandra Piotrowska, Debadeep Chaudhury, Bondita Dehingia, Eryk Duński

Cell Stem Cell· March 2025

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Imaging PD-L1 in the brain-Journey from the lab to the clinic.
Dawoud Dar, Magdalena Rodak, Chiara Da Pieve, Izabela Gorczewska, Gitanjali Sharma, Marcin Niedbala

Neuro Oncol· February 2025

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Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRAS with Demonstrable CNS Penetration.
Jason G Kettle, Sharan K Bagal, Derek Barratt, Michael S Bodnarchuk, Scott Boyd, Michael J Niedbala

J Med Chem· July 2023

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