Publications by authors named "Marcus Scotti"

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Drug design and synthesis of new N-substituted-thienopyridine based on 2-aminothiophene derivatives as antileishmanial agents.
Vitória Gaspar Bernardo, Rodrigo Santos Aquino de Araújo, Natália Barbosa de Mélo, Ricardo Eduardo Pereira Coutinho, Julyanne Maria Saraiva de Sousa, Marcus Tullius Scotti

Bioorg Med Chem· January 2026

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Novel indole-based marinoquinolines as promising candidates against Toxoplasma gondii.
Wellington da Silva, Tayline Torres, Renata Priscila Barros de Menezes, Marcus Tullius Scotti, Juliana Quero Reimão

Eur J Med Chem· December 2025

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Identification of potential mediators of moxidectin-induced developmental toxicity using network toxicology and structure-based analyses.
Cleyton de Sousa Gomes, Juliana Alves da Costa Ribeiro Souza, Natália Ferreira de Sousa, Mayara Dos Santos Maia, Rafael Xavier Martins, Marcus Tullius Scotti

Ecotoxicology· December 2025

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Fabaceae Flavonoids Beyond the Commonplace: A Review of Chemical Diversity, Pharmacological Activities, Mass Spectrometric Profiling and Insights into Their Subclasses.
Ana Rita Rodrigues de Almeida Silva Brilhante, Gabriela Ribeiro de Sousa, Ana Karoline Silva de Aquino-Vital, Natanael Teles Ramos de Lima, Ranna Beatris de Lima Souza, Marcus Tullius Scotti

Plants (Basel)· November 2025

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Orofacial antinociceptive effect of a novel 2-amino-thiophene derivative and its possible targets of action.
Alleson Jamesson da Silva, Pablo Rayff da Silva, Hugo Fernandes Oliveira Pires, Arthur Lins Dias, Cícero Francisco Bezerra Felipe, Marcus Tullius Scotti

Braz Oral Res· October 2025

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Inhibitory effects against SARS-COV-2 main protease of terpenic substances and selenated naphthoquinones.
Marcos R Scheide, Tiago Tizziani, Gabriella B Souza, Francisco F de Assis, Eufrânio N da Silva Júnior, Marcus T Scotti

Nat Prod Res· September 2025

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Conserved Filovirus Proteins as Targets of Broad-Spectrum Antivirals.
Marcus Tullius Scotti, Enes Kelestemur, Holli-Joi Martin, Brandon Novy, Cleber C Melo-Filho

bioRxiv· September 2025

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AmIActive (AIA): A Large-scale QSAR Based Target Fishing and Polypharmacology Predictive Web Tool.
Luis Felipe de Morais Melo, Luciano Pereira de Oliveira Filho, Uilames de Assis Ferreira, Eduardo Henrique Pessoa Alves, Renan Paiva Oliveira Costa, Luciana Scotti, Marcus Tullius Scotti

J Mol Biol· August 2025

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Targets Involved in the Pharmacology of Bothrops Snakebite: and Future Perspectives.
Alisson Emannuel Franco Alves, Allessya Lara Dantas Formiga, Ana Flavia Chaves Uchoa, Anny Leticia Marinho Ramos Cardoso, Eduardo Oliveira Aquino Leal Rodrigues, Marcus Tullius Scotti, Luciana Scotti

Curr Drug Targets· July 2025

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Whole genome sequence of petroleum hydrocarbon degrading novel strain Microbacter sp. EMBS2025 isolated from Chilika Lake, Odisha, India.
Anuraj Nayarisseri, Khushboo Sharma, Arshiya Khan, Radhika Swami, Rinku Chaudhary, Marcus T Scotti, Luciana Scotti

Sci Rep· July 2025

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Hybrid Compounds in Polypharmacology.
Luciana Scotti, Marcus T Scotti

Curr Top Med Chem· June 2025

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Dolichocarpols G-X: Previously undescribed macrocyclic humulene sesquiterpenoids from Anaxagorea dolichocarpa.
Rodrigo Silva de Andrade, Kaio Aragão Sales, Edileuza Bezerra de Assis, Lucas Silva Abreu, Ana Carolina Ferreira de Albuquerque, Marcus Tullius Scotti

Phytochemistry· May 2025

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Larvicidal potential of Knoevenagel adducts against : theoretical study and validation.
Paloma G Abrantes, Poliana G Abrantes, Renata R Magalhães, Gildilayne M Silva, Natália F Sousa, Marcus T Scotti

Future Med Chem· May 2025

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Multiple targets directed screening of compounds from northeastern Brazilian fruits with activity in oxidative stress pathways associated with vascular damage throughout ageing.
Geovânia Maria Sales de Menezes, Mayara Dos Santos Maia, Natália Ferreira de Sousa, Adhonias Correia Dos Santos, Letícia Menezes Cahino, Marcus Tullius Scotti

Nat Prod Res· May 2025

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ADME Properties in Drug Delivery.
Luciana Scotti, Marcus Tullius Scotti

Pharmaceutics· May 2025

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Exploring Lamiaceae diterpenoids as potential multitarget therapeutics for leishmaniasis and chagas disease.
Renata Priscila Barros de Menezes, Edileuza Bezerra de Assis, Natália Ferreira de Sousa, Jullyanne Maria Saraiva de Souza, Klinger Antônio da França Rodrigues, Luciana Scotti, Marcus Tullius Scotti

Mol Divers· April 2025

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4-Hydroxycoumarin Exhibits Antinociceptive and Anti-Inflammatory Effects Through Cytokine Modulation: An Integrated In Silico and In Vivo Study.
Diogo Vilar da Fonsêca, Juliana Sousa Rocha, Pablo R da Silva, Hugo Natan de Sá Novaes Pereira, Lucas Vinicius Novaes Dos Santos, Marcus T Scotti, Luciana Scotti

Int J Mol Sci· March 2025

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Host-Mediated Antimicrobial Effects and NLRP3 Inflammasome Modulation by Caulerpin and Its Derivatives in Macrophage Models of Mycobacterial Infections.
Maria Gabriella S Sidrônio, Maria Eugênia G Freitas, Daniel W A Magalhães, Deyse C M Carvalho, Vinícius A B Gonçalves, Marcus T Scotti

Microorganisms· March 2025

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Preclinical Evaluation of Selene-Ethylenelacticamides in Tuberculosis: Effects Against Active, Dormant, and Resistant and In Vitro Toxicity Investigation.
Natália Ferreira de Sousa, Maria Eugênia G de Freitas, Maria Gabriella S Sidrônio, Helivaldo Diógenes Souza, Alexia Czeczot, Luciana Scotti, Marcus T Scotti

Microorganisms· February 2025

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Repeated-Dose Toxicity of Lauric Acid and Its Preventive Effect Against Tracheal Hyper-Responsiveness in Wistar Rats with Possible Molecular Targets.
Indyra Alencar Duarte Figueiredo, Alissa Maria de Oliveira Martins, Alexya Mikelle Teixeira Cavalcanti, Jayne Muniz Fernandes, Ludmila Emilly da Silva Gomes, Luciana Scotti, Marcus Tullius Scotti

Pharmaceuticals (Basel)· February 2025

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Predicting the Anti-SARS-CoV-2 Potential of Isoquinoline Alkaloids from Brazilian Siparunaceae Species Using Chemometric Tools.
Brendo Araujo Gomes, Diégina Araújo Fernandes, Simony Carvalho Mendonça, Mariana Freire Campos, Thamirys Silva da Fonseca, Marcus Tullius Scotti

Int J Mol Sci· January 2025

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Guanidines Conjugated with Cell-Penetrating Peptides: A New Approach for the Development of Antileishmanial Molecules.
João Victor Marcelino de Souza, Natalia C S Costa, Maria C O Arruda Brasil, Luana Ribeiro Dos Anjos, Renata Priscila Barros de Menezes, Luciana Scotti, Marcus Tullius Scotti

Molecules· January 2025

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2-Aminothiophene Derivatives-New Drug Candidates Against Leishmaniasis: Drug Design, Synthesis, Pharmacomodulation, and Antileishmanial Activity.
Rodrigo Santos Aquino de Araújo, Vitória Gaspar Bernardo, Robert da Silva Tibúrcio, Danilo Cesar Galindo Bedor, Michel Leandro de Campos, Marcus Tullius Scotti

Pharmaceuticals (Basel)· January 2025

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Inhibitory Effects of Secondary Metabolites and Their Synthetic Derivatives against SARS-CoV-2 M and NS2B/NS3 (ZIKV and DENV-2).
Gabriella B Souza, Carime L M Pontes, Geovanna de O Costa, Natália F de Sousa, Tiago Tizziani, Marcus T Scotti

ACS Omega· November 2024

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AMTAC-19, a Spiro-Acridine Compound, Induces In Vitro Antitumor Effect via the ROS-ERK/JNK Signaling Pathway.
Valgrícia Matias de Sousa, Sâmia Sousa Duarte, Rafael Carlos Ferreira, Natália Ferreira de Sousa, Marcus Tullius Scotti, Luciana Scotti

Molecules· November 2024

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