Publications by authors named "Maria Costi"

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Identification of pyrazolo-piperidinone derivatives targeting YAP-TEAD interface 3 as anticancer agents through integrated virtual screening and mass spectrometry proteomics.
Laura Scalvini, Lorenzo Tagliazucchi, Gian Marco Elisi, Dana Zappaterra, Maria Gaetana Moschella, Maria Paola Costi

Eur J Med Chem· December 2025

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Persistent myeloid cell reprogramming despite miltefosine treatment in leishmania-infected macaques.
Morgane Picard, Steven Boutrais, Vasco Rodrigues, Yasmina Fortier, Chloé Borde, Maria Paola Costi

iScience· December 2025

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Mass Spectrometry Proteomics: A Key to Faster Drug Discovery.
Lorenzo Tagliazucchi, Maria Paola Costi

J Med Chem· December 2025

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Design of 2-Aminobenzothiazole Derivatives Targeting Trypanosomatid PTR1 by a Multidisciplinary Fragment Hybridization Approach.
Joanna Panecka-Hofman, Pasquale Linciano, Ina Pöhner, Edyta Dyguda-Kazimierowicz, Wiktoria Jedwabny, Maria Paola Costi

J Med Chem· October 2025

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One Health and Vector-Borne Parasitic Diseases Virtual Special Issue.
Maria Paola Costi, Anabela Cordeiro da Silva

ACS Infect Dis· December 2024

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Drugs for Vector-Borne Protozoal Diseases in a One Health Scenario. A European Perspective.
Anabela Cordeiro da Silva, Theodora Calogeropoulou, Maria Paola Costi, José María Alunda

ACS Infect Dis· November 2024

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Environmental impacts of drugs against parasitic vector-borne diseases and the need to integrate sustainability into their development and use.
Clara M Lima, Elisa Uliassi, Eli S J Thoré, Michael G Bertram, Luis Cardoso, Maria Paola Costi

Open Res Eur· November 2024

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Enhanced anticancer effect of thymidylate synthase dimer disrupters by promoting intracellular accumulation.
Gaetano Marverti, Maria Gaetana Moschella, Alice Belardo, Michele Lamesta, Giada Mercanile, Maria Paola Costi

Front Pharmacol· November 2024

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Biochemical characterization of the feedforward loop between CDK1 and FOXM1 in epidermal stem cells.
Maria Pia Polito, Alessio Romaldini, Lorenzo Tagliazucchi, Grazia Marini, Federica Radice, Maria Paola Costi

Biol Direct· October 2024

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Deciphering Host-Parasite Interplay in Infection through a One Health View of Proteomics Studies on Drug Resistance.
Lorenzo Tagliazucchi, Diego Pinetti, Filippo Genovese, Giulia Malpezzi, Ana Perea Martinez, Maria Paola Costi

ACS Infect Dis· September 2024

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Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti- Agents.
Valeria Francesconi, Marco Rizzo, Cecilia Pozzi, Lorenzo Tagliazucchi, Claude U Konchie Simo, Maria Paola Costi

ACS Infect Dis· August 2024

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One Health.
Michael G Bertram, Maria Paola Costi, Eli S J Thoré, Tara Sabo-Attwood, Bryan W Brooks

Curr Biol· June 2024

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Assessing Environmental Risks during the Drug Development Process for Parasitic Vector-Borne Diseases: A Critical Reflection.
Kayhan Ilbeigi, Carlos Barata, João Barbosa, Michael G Bertram, Guy Caljon, Maria Paola Costi

ACS Infect Dis· April 2024

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The discovery of aryl-2-nitroethyl triamino pyrimidines as anti-Trypanosoma brucei agents.
Pasquale Linciano, Cecilia Pozzi, Giusy Tassone, Giacomo Landi, Stefano Mangani, Maria Paola Costi

Eur J Med Chem· January 2024

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High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents.
Pasquale Linciano, Antonio Quotadamo, Rosaria Luciani, Matteo Santucci, Kimberley M Zorn, Maria Paola Costi

J Med Chem· November 2023

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Label-Free Mass Spectrometry Proteomics Reveals Different Pathways Modulated in THP-1 Cells Infected with Therapeutic Failure and Drug Resistance Clinical Isolates.
Lorenzo Tagliazucchi, Ana Perea-Martinez, Greta Fiorini, José Ignacio Manzano, Filippo Genovese, Maria Paola Costi

ACS Infect Dis· March 2023

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Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective.
Cecilia Pozzi, Anne Vanet, Valeria Francesconi, Lorenzo Tagliazucchi, Giusy Tassone, Maria P Costi

J Med Chem· March 2023

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Serum Mass Spectrometry Proteomics and Protein Set Identification in Response to FOLFOX-4 in Drug-Resistant Ovarian Carcinoma.
Domenico D'Arca, Leda Severi, Stefania Ferrari, Luca Dozza, Gaetano Marverti, Maria Paola Costi

Cancers (Basel)· January 2023

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Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.
Luca Costantino, Stefania Ferrari, Matteo Santucci, Outi M H Salo-Ahen, Emanuele Carosati, Maria Paola Costi

Elife· December 2022

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Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1.
Ina Pöhner, Antonio Quotadamo, Joanna Panecka-Hofman, Rosaria Luciani, Matteo Santucci, Maria P Costi

J Med Chem· July 2022

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Olaparib beyond progression compared with platinum chemotherapy after secondary cytoreductive surgery in patients with recurrent ovarian cancer: phase III randomized, open-label MITO 35b study, a project of the MITO-MANGO groups.
Clorinda Schettino, Lucia Musacchio, Michele Bartoletti, Paolo Chiodini, Laura Arenare, Maria Paola Costi

Int J Gynecol Cancer· June 2022

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Current Treatments to Control African Trypanosomiasis and One Health Perspective.
Alberto Venturelli, Lorenzo Tagliazucchi, Clara Lima, Federica Venuti, Giulia Malpezzi, Maria Paola Costi

Microorganisms· June 2022

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Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library.
Angela Lauriola, Elisa Uliassi, Matteo Santucci, Maria Laura Bolognesi, Marco Mor, Maria Paola Costi

Pharmaceutics· February 2022

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Sesquiterpene Lactones with Dual Inhibitory Activity against the Pteridine Reductase 1 and Dihydrofolate Reductase.
Katharina Possart, Fabian C Herrmann, Joachim Jose, Maria P Costi, Thomas J Schmidt

Molecules· December 2021

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Repurposing the Trypanosomatidic GSK Kinetobox for the Inhibition of Parasitic Pteridine and Dihydrofolate Reductases.
Matteo Santucci, Rosaria Luciani, Eleonora Gianquinto, Cecilia Pozzi, Flavio di Pisa, Maria Paola Costi

Pharmaceuticals (Basel)· November 2021

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