Publications by authors named "Marios Georgakis"

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Human genetics implicate thromboembolism in the pathogenesis of long COVID in individuals of European ancestry.
Art Schuermans, Andreas Verstraete, Vilma Lammi, Tomoko Nakanishi, Maddalena Ardissino, Marios K Georgakis

Nat Cardiovasc Res· December 2025

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Anti-Inflammatory Therapies for Atherosclerotic Stroke Prevention.
Marios K Georgakis, Philip Melton, Luka Živković, Anna Kopczak, Aristeidis H Katsanos

Neurology· November 2025

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Longitudinal Association of a Polygenic Risk Score for Plasma T-Tau With Incident Alzheimer Dementia and Mild Cognitive Impairment.
Niki Mourtzi, Sokratis Charisis, Eva Ntanasi, Alexandros Hatzimanolis, Alfredo Ramirez, Marios K Georgakis

Neurology· November 2025

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Genetic Downregulation of Interleukin-6 Signaling and Arteriolosclerotic Cerebral Small Vessel Disease: A Drug Target Mendelian Randomization Analysis.
Larissa Ange Tchuisseu-Kwangoua, Murad Omarov, Alexey Shatunov, Hugh S Markus, Joseph Kamtchum-Tatuene, Marios K Georgakis

J Am Heart Assoc· November 2025

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Data-Driven Discovery of Novel Biology: From Genetics and Omics to Therapeutic Targets for Vascular Disease.
Marios K Georgakis

JACC Basic Transl Sci· October 2025

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Automated Deep Learning-Based Detection of Early Atherosclerotic Plaques in Carotid Ultrasound Imaging.
Murad Omarov, Lanyue Zhang, Saman Doroodgar Jorshery, Rainer Malik, Barnali Das, Marios K Georgakis

medRxiv· September 2025

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IL6 genetic perturbation mimicking IL-6 inhibition is associated with lower cardiometabolic risk.
Lanyue Zhang, Murad Omarov, Lingling Xu, Emil deGoma, Pradeep Natarajan, Marios K Georgakis

Nat Cardiovasc Res· September 2025

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Risk factors for dementia and cognitive impairment within 5 years after stroke: a prospective multicentre cohort study.
Jule Filler, Marios K Georgakis, Daniel Janowitz, Marco Duering, Rong Fang

Lancet Reg Health Eur· September 2025

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Genetic Risk Scores in Stroke Research and Care.
Nicola Luigi Bragazzi, Lanyue Zhang, Murad Omarov, Marios K Georgakis

Stroke· August 2025

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Human Genetics Informing Drug Development in Cardiovascular Disease: Interleukin-6 Signaling as a Case Study.
Emil deGoma, John Walsh, Marios K Georgakis

Circ Genom Precis Med· August 2025

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Circulating cytokine levels and 5-year vascular recurrence after stroke: A multicenter prospective cohort study.
Lanyue Zhang, Mohamad Ali Antabi, Jana Mattar, Omar El Bounkari, Rong Fang, Marios K Georgakis

Eur Stroke J· August 2025

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Cross-tissue omics-guided drug repurposing triangulates novel targetable mechanisms for Alzheimer's disease and candidate genetic biomarkers for treatment stratification.
Sathyaseelan Chakkarai, Michal Sadowski, Qiong Yang, Anushree Ray, Ruiqi Wang, Marios K Georgakis

Res Sq· August 2025

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Single-cell transcriptome-wide Mendelian randomization and colocalization analyses uncover cell-specific mechanisms in atherosclerotic cardiovascular disease.
Anushree Ray, Paulo Alabarse, Rainer Malik, Muralidharan Sargurupremraj, Jürgen Bernhagen, Marios K Georgakis

Am J Hum Genet· July 2025

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Proteomic Signatures as Biomarkers of Atherosclerosis Burden.
Lanyue Zhang, Murad Omarov, LingLing Xu, Barnali Das, Hong Luo, Marios K Georgakis

Res Sq· June 2025

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A Beneficial Role for Gluteofemoral Adipose Tissue in Cerebrovascular Disease: Causal Pathway and Mediation Analysis.
Evangelos Pavlos Myserlis, Marios K Georgakis, Livia Parodi, Ernst Mayerhofer, Murad Omarov

Neurology· May 2025

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Serum anti-NMDA receptor antibodies are linked to memory impairment 12 months after stroke.
Friederike A Arlt, Pia S Sperber, Regina von Rennenberg, Pimrapat Gebert, Bianca Teegen, Marios K Georgakis

Mol Psychiatry· April 2025

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Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk.
Marios K Georgakis, Rainer Malik, Omar El Bounkari, Natalie R Hasbani, Jiang Li

Genome Med· March 2025

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Genetically Predicted IL-18 Inhibition and Risk of Cardiovascular Events: A Mendelian Randomization Study.
Stephen O Brennan, Peter J Kelly, Sarah Gorey, Pádraig Synnott, Dipender Gill, Marios K Georgakis

Circulation· February 2025

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Exploring Synaptic Pathways in Traumatic Brain Injury: A Cross-Phenotype Genomics Approach.
Savvina Prapiadou, Ernst Mayerhofer, Marios K Georgakis, Mart Kals, Farid Radmanesh

J Neurotrauma· January 2025

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The genomic architecture of circulating cytokine levels points to drug targets for immune-related diseases.
Marek J Konieczny, Murad Omarov, Lanyue Zhang, Rainer Malik, Tom G Richardson, Marios K Georgakis

Commun Biol· January 2025

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Genetic predisposition to high circulating levels of interleukin 6 and risk for Alzheimer's disease. Discovery and replication.
Sokratis Charisis, Niki Mourtzi, Matthew R Scott, Eva Ntanasi, Eirini Mamalaki, Marios Κ Georgakis

J Prev Alzheimers Dis· January 2025

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Risk factors and clinical significance of post-stroke incident ischemic lesions.
Rong Fang, Marco Duering, Felix J Bode, Sebastian Stösser, Julius N Meißner, Marios K Georgakis

Alzheimers Dement· December 2024

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The role of the gluteofemoral adipose tissue in cerebrovascular disease risk: evidence from a mendelian randomization and mediation analysis.
Evangelos Pavlos Myserlis, Marios K Georgakis, Livia Parodi, Ernst Mayerhofer, Jonathan Rosand

medRxiv· August 2024

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Genetically proxied IL-6 signaling and risk of Alzheimer's disease and lobar intracerebral hemorrhage: A drug target Mendelian randomization study.
Evangelos Pavlos Myserlis, Anushree Ray, Christopher D Anderson, Marios K Georgakis

Alzheimers Dement (N Y)· August 2024

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Genetically proxied HTRA1 protease activity and circulating levels independently predict risk of ischemic stroke and coronary artery disease.
Rainer Malik, Nathalie Beaufort, Jiang Li, Koki Tanaka, Marios K Georgakis

Nat Cardiovasc Res· June 2024

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