Publications by authors named "Marta D Costa"

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A substantial prehistoric European ancestry amongst Ashkenazi maternal lineages.
Marta D Costa, Joana B Pereira, Maria Pala, Verónica Fernandes, Anna Olivieri, Alessandro Achilli, Ugo A Perego, Sergei Rychkov, Oksana Naumova, Jiři Hatina

Nat Commun· May 2014

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Differential effects of lifespan-extending genetic manipulations in an animal model of MJD/SCA3.
Marta Daniela Costa, Jorge Diogo Da Silva, Dulce Almeida, Joana Pereira-Sousa, Daniela Vilasboas-Campos

Mech Ageing Dev· June 2025

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Therapeutic Effects of Baroni Extract on Animal Models of Neurodegenerative Diseases Through Serotonin and HLH-30/TFEB-Dependent Mechanisms.
Jorge H Fernandes, Marta Daniela Costa, Daniela Vilasboas-Campos, Bruna Ferreira-Lomba, Joana Pereira-Sousa

Int J Mol Sci· April 2025

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Differential impact of diesel exhaust particles on glutamatergic and dopaminergic neurons in Caenorhabditis elegans: A neurodegenerative perspective.
Nivedita Chatterjee, Michael González-Durruthy, Marta Daniela Costa, Ana R Ribeiro, Vânia Vilas-Boas

Environ Int· April 2024

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and evaluation of novel chromeno[2,3-]pyrimidinones as therapeutic agents for triple negative breast cancer.
Luísa Carvalho, Fábio Pedroso de Lima, Mónica Cerqueira, Ana Silva, Olívia Pontes, Marta D Costa, Marta Costa

RSC Med Chem· April 2024

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Glucocorticoid receptor-dependent therapeutic efficacy of tauroursodeoxycholic acid in preclinical models of spinocerebellar ataxia type 3.
Sara Duarte-Silva, Jorge Diogo Da Silva, Daniela Monteiro-Fernandes, Marta Daniela Costa, Andreia Neves-Carvalho, Liliana Meireles-Costa

J Clin Invest· March 2024

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Mitochondrial Dysfunction and Decreased Cytochrome in Cell and Animal Models of Machado-Joseph Disease.
Filipa Almeida, Ildete L Ferreira, Luana Naia, Daniela Marinho, Ana Catarina Vilaça-Ferreira, Marta D Costa

Cells· October 2023

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Modifier pathways in polyglutamine (PolyQ) diseases: from genetic screens to drug targets.
Marta Daniela Costa, Patrícia Maciel

Cell Mol Life Sci· May 2022

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Aripiprazole Offsets Mutant ATXN3-Induced Motor Dysfunction by Targeting Dopamine D and Serotonin 1A and 2A Receptors in .
Ana Jalles, Cármen Vieira, Joana Pereira-Sousa, Daniela Vilasboas-Campos, Ana Francisca Mota, Marta Daniela Costa

Biomedicines· February 2022

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Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing.
Mafalda Raposo, Conceição Bettencourt, Ana Rosa Vieira Melo, Ana F Ferreira, Isabel Alonso, Marta D Costa

Neurobiol Dis· January 2022

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Case Report: A Novel Mutation Causes Global Developmental Delay With Intellectual Disability and Behavioral Disorders.
Jorge Diogo Da Silva, Marta Daniela Costa, Bruno Almeida, Fátima Lopes, Patrícia Maciel

Front Neurol· September 2021

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Identification of the 5-HT serotonin receptor as a novel therapeutic target in a C. elegans model of Machado-Joseph disease.
Joana Pereira-Sousa, Bruna Ferreira-Lomba, Aina Bellver-Sanchis, Daniela Vilasboas-Campos, Jorge H Fernandes, Marta D Costa

Neurobiol Dis· May 2021

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Neurotherapeutic effect of Hyptis spp. leaf extracts in Caenorhabditis elegans models of tauopathy and polyglutamine disease: Role of the glutathione redox cycle.
Daniela Vilasboas-Campos, Marta Daniela Costa, Andreia Teixeira-Castro, Rejaine Rios, Fabiano Guimarães Silva

Free Radic Biol Med· January 2021

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Data on the effects of spp. and spp. plant extracts in models of genetically determined neurodegenerative diseases.
Daniela Vilasboas-Campos, Marta Daniela Costa, Andreia Teixeira-Castro, Rejaine Rios, Fabiano Guimarães Silva

Data Brief· December 2020

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Unravelling the anticancer potential of functionalized chromeno[2,3-b]pyridines for breast cancer treatment.
Sofia Oliveira-Pinto, Olívia Pontes, Diogo Lopes, Belém Sampaio-Marques, Marta D Costa, Bruno M Costa, Marta Costa

Bioorg Chem· July 2020

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Loss of egli-1, the Caenorhabditis elegans Orthologue of a Downstream Target of SMN, Leads to Abnormalities in Sensorimotor Integration.
Jorge Diogo Da Silva, Stéphanie Oliveira, Joana Pereira-Sousa, Andreia Teixeira-Castro, Marta Daniela Costa

Mol Neurobiol· March 2020

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GST-4-Dependent Suppression of Neurodegeneration in Models of Parkinson's and Machado-Joseph Disease by Rapeseed Pomace Extract Supplementation.
Franziska Pohl, Andreia Teixeira-Castro, Marta Daniela Costa, Victoria Lindsay, Juliana Fiúza-Fernandes

Front Neurosci· October 2019

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Origin and spread of human mitochondrial DNA haplogroup U7.
Hovhannes Sahakyan, Baharak Hooshiar Kashani, Rakesh Tamang, Alena Kushniarevich, Amirtharaj Francis, Marta D Costa

Sci Rep· April 2017

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Reconciling evidence from ancient and contemporary genomes: a major source for the European Neolithic within Mediterranean Europe.
Joana B Pereira, Marta D Costa, Daniel Vieira, Maria Pala, Lisa Bamford

Proc Biol Sci· March 2017

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Fine Time Scaling of Purifying Selection on Human Nonsynonymous mtDNA Mutations Based on the Worldwide Population Tree and Mother-Child Pairs.
Bruno Cavadas, Pedro Soares, Rui Camacho, Andreia Brandão, Marta D Costa

Hum Mutat· November 2015

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The Expansion of mtDNA Haplogroup L3 within and out of Africa.
Pedro Soares, Farida Alshamali, Joana B Pereira, Verónica Fernandes, Nuno M Silva, Marta D Costa

Mol Biol Evol· March 2012

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The Arabian cradle: mitochondrial relicts of the first steps along the southern route out of Africa.
Verónica Fernandes, Farida Alshamali, Marco Alves, Marta D Costa, Joana B Pereira

Am J Hum Genet· February 2012

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Population expansion in the North African late Pleistocene signalled by mitochondrial DNA haplogroup U6.
Luísa Pereira, Nuno M Silva, Ricardo Franco-Duarte, Verónica Fernandes, Joana B Pereira, Marta D Costa

BMC Evol Biol· December 2010

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The trans-Saharan slave trade - clues from interpolation analyses and high-resolution characterization of mitochondrial DNA lineages.
Nourdin Harich, Marta D Costa, Verónica Fernandes, Mostafa Kandil, Joana B Pereira

BMC Evol Biol· May 2010

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The diversity present in 5140 human mitochondrial genomes.
Luísa Pereira, Fernando Freitas, Verónica Fernandes, Joana B Pereira, Marta D Costa, Stephanie Costa

Am J Hum Genet· May 2009

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