Publications by authors named "Martin D Brand"

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Assessing mitochondrial dysfunction in cells.
Martin D Brand, David G Nicholls

April 2011

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Mitochondrial respiratory complex III sustains IL-10 production in activated macrophages and promotes tumor-mediated immune evasion.
Alessia Zotta, Juliana Toller-Kawahisa, Eva M Palsson-McDermott, Shane M O'Carroll, Órlaith C Henry, Martin D Brand

Sci Adv· January 2025

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Exogenous expression of ATP8, a mitochondrial encoded protein, from the nucleus .
David V Begelman, Bhavna Dixit, Carly Truong, Christina D King, Mark A Watson, Martin D Brand

Mol Ther Methods Clin Dev· December 2024

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Hypoxia decreases mitochondrial ROS production in cells.
Bijoya Sen, Bérengère Benoit, Martin D Brand

Free Radic Biol Med· November 2024

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Suppression of superoxide/hydrogen peroxide production at mitochondrial site I decreases fat accumulation, improves glucose tolerance and normalizes fasting insulin concentration in mice fed a high-fat diet.
Mark A Watson, Harmanmeet Brar, Edwin T Gibbs, Hoi-Shan Wong, Pratiksha A Dighe, Martin D Brand

Free Radic Biol Med· August 2023

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Site IQ in mitochondrial complex I generates S1QEL-sensitive superoxide/hydrogen peroxide in both the reverse and forward reactions.
Edwin T Gibbs, Chad A Lerner, Mark A Watson, Hoi-Shan Wong, Akos A Gerencser, Martin D Brand

Biochem J· March 2023

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A critical assessment of the role of creatine in brown adipose tissue thermogenesis.
David G Nicholls, Martin D Brand

Nat Metab· January 2023

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Effects of sugars, fatty acids and amino acids on cytosolic and mitochondrial hydrogen peroxide release from liver cells.
Jingqi Fang, Yini Zhang, Akos A Gerencser, Martin D Brand

Free Radic Biol Med· August 2022

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Controlled power: how biology manages succinate-driven energy release.
Shona A Mookerjee, Akos A Gerencser, Mark A Watson, Martin D Brand

Biochem Soc Trans· December 2021

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S3QELs protect against diet-induced intestinal barrier dysfunction.
Mark A Watson, Blaine Pattavina, Tyler A U Hilsabeck, Jose Lopez-Dominguez, Pankaj Kapahi, Martin D Brand

Aging Cell· October 2021

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Cardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H O production in heart and skeletal muscle mitochondria.
Renata L S Goncalves, Michael Schlame, Alexander Bartelt, Martin D Brand, Gökhan S Hotamışlıgil

FEBS Lett· February 2021

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Superoxide produced by mitochondrial site I inactivates cardiac succinate dehydrogenase and induces hepatic steatosis in Sod2 knockout mice.
Hoi-Shan Wong, Vojtech Mezera, Pratiksha Dighe, Simon Melov, Akos A Gerencser, Martin D Brand

Free Radic Biol Med· February 2021

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Riding the tiger - physiological and pathological effects of superoxide and hydrogen peroxide generated in the mitochondrial matrix.
Martin D Brand

Crit Rev Biochem Mol Biol· December 2020

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Production of superoxide and hydrogen peroxide in the mitochondrial matrix is dominated by site I of complex I in diverse cell lines.
Jingqi Fang, Hoi-Shan Wong, Martin D Brand

Redox Biol· October 2020

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The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production.
Renata L S Goncalves, Mark A Watson, Hoi-Shan Wong, Adam L Orr, Martin D Brand

Redox Biol· January 2020

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S1QELs suppress mitochondrial superoxide/hydrogen peroxide production from site I without inhibiting reverse electron flow through Complex I.
Hoi-Shan Wong, Pierre-Axel Monternier, Martin D Brand

Free Radic Biol Med· November 2019

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Use of S1QELs and S3QELs to link mitochondrial sites of superoxide and hydrogen peroxide generation to physiological and pathological outcomes.
Mark A Watson, Hoi-Shan Wong, Martin D Brand

Biochem Soc Trans· October 2019

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The Whys and Hows of Calculating Total Cellular ATP Production Rate.
Megan E Handel, Martin D Brand, Shona A Mookerjee

Trends Endocrinol Metab· July 2019

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Measurement of Proton Leak in Isolated Mitochondria.
Charles Affourtit, Hoi-Shan Wong, Martin D Brand

Methods Mol Biol· February 2019

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Plate-Based Measurement of Superoxide and Hydrogen Peroxide Production by Isolated Mitochondria.
Hoi-Shan Wong, Pierre-Axel Monternier, Adam L Orr, Martin D Brand

Methods Mol Biol· February 2019

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Plate-Based Measurement of Respiration by Isolated Mitochondria.
Shona A Mookerjee, Casey L Quinlan, Hoi-Shan Wong, Pratiksha Dighe, Martin D Brand

Methods Mol Biol· February 2019

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Mitochondrial and cytosolic sources of hydrogen peroxide in resting C2C12 myoblasts.
Hoi-Shan Wong, Bérengère Benoit, Martin D Brand

Free Radic Biol Med· January 2019

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Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements.
Shona A Mookerjee, Akos A Gerencser, David G Nicholls, Martin D Brand

J Biol Chem· August 2018

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Osteoblast-like MC3T3-E1 Cells Prefer Glycolysis for ATP Production but Adipocyte-like 3T3-L1 Cells Prefer Oxidative Phosphorylation.
Anyonya R Guntur, Akos A Gerencser, Phuong T Le, Victoria E DeMambro, Sheila A Bornstein, Martin D Brand

J Bone Miner Res· June 2018

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Generation of superoxide and hydrogen peroxide by side reactions of mitochondrial 2-oxoacid dehydrogenase complexes in isolation and in cells.
Victoria I Bunik, Martin D Brand

Biol Chem· April 2018

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Comparison of Mitochondrial Reactive Oxygen Species Production of Ectothermic and Endothermic Fish Muscle.
Lilian Wiens, Sheena Banh, Emianka Sotiri, Martin Jastroch, Barbara A Block, Martin D Brand

Front Physiol· September 2017

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