Publications by authors named "Marylyn D Ritchie"

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The phenotypic legacy of admixture between modern humans and Neandertals.
Corinne N Simonti, Benjamin Vernot, Lisa Bastarache, Erwin Bottinger, David S Carrell, Rex L Chisholm, David R Crosslin, Scott J Hebbring, Gail P Jarvik, Iftikhar J Kullo

Science· February 2016

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Author Correction: Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum.
David S M Lee, Kathleen M Cardone, David Y Zhang, Noah L Tsao, Sarah Abramowitz, Marylyn D Ritchie

Nat Genet· December 2025

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Melanocortin-4 Receptor Gene Variants and Weight Change Following Switch to Integrase Inhibitor-Based Antiretroviral Therapy.
Todd Hulgan, Kristine M Erlandson, Yuki Bradford, Katherine Tassiopoulos, Kunling Wu, Marylyn D Ritchie

Open Forum Infect Dis· December 2025

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An African ancestry-specific nonsense variant in CD36 is associated with a higher risk of dilated cardiomyopathy.
Jennifer E Huffman, Liam Gaziano, Zeina R Al Sayed, Renae L Judy, Laura M Raffield, Marylyn D Ritchie

Nat Genet· November 2025

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Integrative multi-omics approaches identify molecular pathways and improve Alzheimer's disease risk prediction.
Rasika Venkatesh, Katie M Cardone, Yuki Bradford, Anni K Moore, Rachit Kumar, Marylyn D Ritchie

Alzheimers Dement· November 2025

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Multimodal Prediction of Primary Open-Angle Glaucoma Using Polygenic Risk Scores and Clinical Features in a High-Risk African Ancestry Cohort.
Yan Zhu, Aude Benigne Ikuzwe Sindikubwabo, Yuki Bradford, Rebecca Salowe, Lannawill Caruth, Marylyn D Ritchie

medRxiv· October 2025

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Endophenotype Guided Genome-Wide Association Study to Enhance Genetic Risk Prediction of Primary Open-Angle Glaucoma in African Ancestry Populations.
Aude Benigne Ikuzwe Sindikubwabo, Lannawill Caruth, Yan Zhu, Yuki Bradford, Rebecca Salowe, Marylyn D Ritchie

medRxiv· October 2025

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Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Roelof A J Smit, Kaitlin H Wade, Qin Hui, Joshua D Arias, Xianyong Yin, Marylyn D Ritchie

Nat Med· September 2025

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A one-shot, lossless algorithm for cross-cohort learning in mixed-outcomes analysis.
Ruowang Li, Luke Benz, Rui Duan, Joshua C Denny, Hakon Hakonarson, Marylyn D Ritchie

Patterns (N Y)· September 2025

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Integrating Imaging-Derived Clinical Endotypes with Plasma Proteomics and External Polygenic Risk Scores Enhances Coronary Microvascular Disease Risk Prediction.
Rasika Venkatesh, Tess Cherlin, , Marylyn D Ritchie, Marie A Guerraty

medRxiv· August 2025

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DRIVE-KG: Enhancing variant-phenotype association discovery in understudied complex diseases using heterogeneous knowledge graphs.
Ananya Rajagopalan, Tram Anh Nguyen, Lindsay A Guare, Andre Luis Garao Rico, Rasika Venkatesh, Marylyn D Ritchie

medRxiv· August 2025

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CASTER-DTA: equivariant graph neural networks for predicting drug-target affinity.
Rachit Kumar, Joseph D Romano, Marylyn D Ritchie

Brief Bioinform· August 2025

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A Pan-Organ Vision-Language Model for Generalizable 3D CT Representations.
Cameron Beeche, Joonghyun Kim, Hamed Tavolinejad, Bingxin Zhao, Rakesh Sharma, Marylyn D Ritchie

medRxiv· July 2025

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Large-scale evaluation of proteomic and polygenic risk scores reveals complementary contributions to incident disease prediction.
Jakob Woerner, Thomas M Westbrook, Jaehyun Joo, Manu Shivakumar, Rasika Venkatesh, Marylyn D Ritchie

medRxiv· July 2025

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The polygenic architecture of hidradenitis suppurativa reveals signaling mechanisms that implicate epithelial remodeling.
Atlas Khan, Poppy A Gould, Yiming Luo, Errol P Prens, Lee Wheless, Marylyn D Ritchie

medRxiv· July 2025

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Protein risk scores enable precise prediction of cardiovascular events in chronic kidney disease patients.
Yang-Gyun Kim, Yonghyun Nam, Thomas M Westbrook, Jaehyun Joo, Jakob Woerner, Marylyn D Ritchie

medRxiv· July 2025

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Leveraging Social Determinants of Health in Alzheimer's Research Using LLM-Augmented Literature Mining and Knowledge Graphs.
Tianqi Shang, Shu Yang, Weiqing He, Tianhua Zhai, Dawei Li, Marylyn D Ritchie

AMIA Jt Summits Transl Sci Proc· June 2025

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Integrative multi-omics approaches identify molecular pathways and improve Alzheimer's Disease risk prediction.
Rasika Venkatesh, Katie M Cardone, Yuki Bradford, Anni K Moore, Rachit Kumar, Marylyn D Ritchie

medRxiv· June 2025

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Genetic polymorphisms and adverse reactions to antituberculosis therapy.
Hannah M Gunter, Phuti Choshi, Tafadzwa Chimbetete, Sarah Pedretti, Rannakoe J Lehloenya, Marylyn D Ritchie

Pharmacogenomics· June 2025

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Ensuring Fairness in Detecting Mild Cognitive Impairment with MRI.
Boning Tong, Travyse Edwards, Shu Yang, Bojian Hou, Davoud Ataee Tarzanagh, Marylyn D Ritchie

AMIA Annu Symp Proc· May 2025

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Network-based analyses of multiomics data in biomedicine.
Rachit Kumar, Joseph D Romano, Marylyn D Ritchie

BioData Min· May 2025

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A genotype-first approach identifies high incidence of NF1 pathogenic variants with distinct disease associations.
Anton Safonov, Tomoki T Nomakuchi, Elizabeth Chao, Carrie Horton, Jill S Dolinsky, Marylyn D Ritchie

Nat Commun· April 2025

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Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum.
David S M Lee, Kathleen M Cardone, David Y Zhang, Noah L Tsao, Sarah Abramowitz, Marylyn D Ritchie

Nat Genet· April 2025

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Discovery of ancestry-specific variants associated with clopidogrel response among Caribbean Hispanics.
Guang Yang, Pablo González, Mariangeli Moneró, Kelvin Carrasquillo, Jessicca Y Renta, Marylyn D Ritchie

NPJ Genom Med· March 2025

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Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants.
Hongbo Liu, Amin Abedini, Eunji Ha, Ziyuan Ma, Xin Sheng, Marylyn D Ritchie

Science· February 2025

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PennPRS: a centralized cloud computing platform for efficient polygenic risk score training in precision medicine.
Jin Jin, Bingxuan Li, Xiyao Wang, Xiaochen Yang, Yujue Li, Marylyn D Ritchie

medRxiv· February 2025

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