Publications by authors named "Matthew Traylor"

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Plasma proteomic associations with genetics and health in the UK Biobank.
Benjamin B Sun, Joshua Chiou, Matthew Traylor, Christian Benner, Yi-Hsiang Hsu, Tom G Richardson, Praveen Surendran, Anubha Mahajan, Chloe Robins, Steven G Vasquez-Grinnell

October 2023

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Mapping atherogenesis mechanisms in smooth muscle cells by targeting genes linked to coronary artery disease.
Julián Albarrán-Juárez, Anton Markov, Anne Louise Jensen, Peter Loof Møller, Anna Katarzyna Uryga, Matthew Traylor

iScience· November 2025

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Interpretable machine learning leverages proteomics to improve cardiovascular disease risk prediction and biomarker identification.
Héctor Climente-González, Min Oh, Urszula Chajewska, Roya Hosseini, Sudipto Mukherjee, Matthew Traylor

Commun Med (Lond)· May 2025

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Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits.
Jacob M Keaton, Zoha Kamali, Tian Xie, Ahmad Vaez, Ariel Williams, Matthew Traylor

Nat Genet· May 2024

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Profiling the genome and proteome of metabolic dysfunction-associated steatotic liver disease identifies potential therapeutic targets.
Jun Liu, Sile Hu, Lingyan Chen, Charlotte Daly, Cesar Augusto Prada Medina, Matthew Traylor

medRxiv· November 2023

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Genetically Encoded Detection of Biosynthetic Protease Inhibitors.
Levi Kramer, Ankur Sarkar, Tom Foderaro, Andrew L Markley, Jessica Lee, Matthew J Traylor

ACS Synth Biol· January 2023

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Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.
Kazuyoshi Ishigaki, Saori Sakaue, Chikashi Terao, Yang Luo, Kyuto Sonehara, Matthew Traylor

Nat Genet· November 2022

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Genetic Evidence for Protective Effects of Angiotensin-Converting Enzyme Against Alzheimer Disease But Not Other Neurodegenerative Diseases in European Populations.
David K Ryan, Ville Karhunen, Bowen Su, Matthew Traylor, Tom G Richardson

Neurol Genet· October 2022

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Systematic Mendelian randomization using the human plasma proteome to discover potential therapeutic targets for stroke.
Lingyan Chen, James E Peters, Bram Prins, Elodie Persyn, Matthew Traylor

Nat Commun· October 2022

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Evolution-Guided Biosynthesis of Terpenoid Inhibitors.
Ankur Sarkar, Tom Foderaro, Levi Kramer, Andrew L Markley, Jessica Lee, Matthew J Traylor

ACS Synth Biol· September 2022

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The BS variant of C4 protects against age-related loss of white matter microstructural integrity.
Matthew Traylor, Rainer Malik, Benno Gesierich, Martin Dichgans

Brain· March 2022

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The Histone Deacetylase 9 Stroke-Risk Variant Promotes Apoptosis and Inflammation in a Human iPSC-Derived Smooth Muscle Cells Model.
Alessandra Granata, Ioannis Kasioulis, Felipe Serrano, James D Cooper, Matthew Traylor

Front Cardiovasc Med· March 2022

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Cardiovascular Risk Factors and MRI Markers of Cerebral Small Vessel Disease: A Mendelian Randomization Study.
Victoria Taylor-Bateman, Dipender Gill, Marios K Georgakis, Rainer Malik, Patricia Munroe, Matthew Traylor

Neurology· January 2022

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Hypertension genetics past, present and future applications.
Kaya J Olczak, Victoria Taylor-Bateman, Hannah L Nicholls, Matthew Traylor, Claudia P Cabrera

J Intern Med· December 2021

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The genetic case for cardiorespiratory fitness as a clinical vital sign and the routine prescription of physical activity in healthcare.
Ken B Hanscombe, Elodie Persyn, Matthew Traylor, Kylie P Glanville, Mark Hamer

Genome Med· November 2021

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Whole-exome sequencing reveals a role of HTRA1 and EGFL8 in brain white matter hyperintensities.
Rainer Malik, Nathalie Beaufort, Simon Frerich, Benno Gesierich, Marios K Georgakis, Matthew Traylor

Brain· October 2021

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VEGFR-1/Flt-1 inhibition increases angiogenesis and improves muscle function in a mouse model of Duchenne muscular dystrophy.
Jennifer Bosco, Zhiwei Zhou, Sofie Gabriëls, Mayank Verma, Nan Liu, Matthew J Traylor

Mol Ther Methods Clin Dev· June 2021

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Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies.
Matthew Traylor, Elodie Persyn, Liisa Tomppo, Sofia Klasson, Vida Abedi

Lancet Neurol· May 2021

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Association of common genetic variants with brain microbleeds: A genome-wide association study.
Maria J Knol, Dongwei Lu, Matthew Traylor, Hieab H H Adams, José Rafael J Romero

Neurology· December 2020

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Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression.
Saskia P Hagenaars, Jonathan R I Coleman, Shing Wan Choi, Héléna Gaspar, Mark J Adams, Matthew Traylor

Am J Med Genet B Neuropsychiatr Genet· September 2020

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Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke.
Keith L Keene, Hyacinth I Hyacinth, Joshua C Bis, Steven J Kittner, Braxton D Mitchell, Matthew Traylor

Stroke· August 2020

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Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants.
Elodie Persyn, Ken B Hanscombe, Joanna M M Howson, Cathryn M Lewis, Matthew Traylor

Nat Commun· May 2020

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Influence of Genetic Variation in on Endothelial Function and Stroke.
Matthew Traylor, Ali Amin Al Olama, Leo-Pekka Lyytikäinen, Sandro Marini, Jaeyoon Chung

Hypertension· February 2020

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The role of haematological traits in risk of ischaemic stroke and its subtypes.
Eric L Harshfield, Matthew C Sims, Matthew Traylor, Willem H Ouwehand, Hugh S Markus

Brain· January 2020

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How common are single gene mutations as a cause for lacunar stroke? A targeted gene panel study.
Rhea Y Y Tan, Matthew Traylor, Karyn Megy, Daniel Duarte, Sri V V Deevi

Neurology· November 2019

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