Publications by authors named "Michael D Greicius"

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Plasma proteomics links brain and immune system aging with healthspan and longevity.
Hamilton Se-Hwee Oh, Yann Le Guen, Nimrod Rappoport, Deniz Yagmur Urey, Amelia Farinas, Jarod Rutledge, Divya Channappa, Anthony D Wagner, Elizabeth Mormino, Anne Brunet

Nat Med· August 2025

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Failure to demonstrate efficacy of aducanumab: An analysis of the EMERGE and ENGAGE trials as reported by Biogen, December 2019.
David S Knopman, David T Jones, Michael D Greicius

April 2021

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A Quarter Century of APOE and Alzheimer's Disease: Progress to Date and the Path Forward.
Michaël E Belloy, Valerio Napolioni, Michael D Greicius

Neuron· March 2019

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The will to persevere induced by electrical stimulation of the human cingulate gyrus.
Josef Parvizi, Vinitha Rangarajan, William R Shirer, Nikita Desai, Michael D Greicius

December 2013

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*4 Risk-Modifying Genes and Drug Targets in Alzheimer's Disease through Cell-Type Specific Genomic Analyses.
Youjie Zeng, Noah Cook, Chenyu Yang, Sathesh K Sivasankaran, Masashi Fujita, Michael D Greicius

medRxiv· December 2025

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ApoE is Secreted as a Lipid Nanoparticle by Mammalian Cells: Implications for Alzheimer's Disease Pathogenesis.
Ricardo Hernandez Arriaza, Dylan Reil, Nina Fatuzzo, Mengying Fu, Yuqin Dai, Michael D Greicius

Biochemistry· November 2025

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Integrative Genetic, Proteogenomic, and Multi-omics Analyses Reveal Sex-Biased Causal Genes and Drug Targets in Alzheimer's Disease.
Noah Cook, Chenyu Yang, Youjie Zeng, Sathesh K Sivasankaran, Soomin Song, Michael D Greicius

medRxiv· November 2025

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Long-read genome sequencing and multi-omics in aging and neurodegeneration.
Tanner D Jensen, Yann Le Guen, Lia Talozzi, Sherry Yang, John Gorzynski, Michael D Greicius

medRxiv· October 2025

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Transferability of European-derived Alzheimer's disease polygenic risk scores across multiancestry populations.
Aude Nicolas, Richard Sherva, Benjamin Grenier-Boley, Yoontae Kim, Masataka Kikuchi, Michael D Greicius

Nat Genet· July 2025

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Synergistic effects of ε4 and Alzheimer's pathology on the neural correlates of episodic remembering in cognitively unimpaired older adults.
Alexandra N Trelle, Jintao Sheng, Edward N Wilson, America Romero, Jennifer Park, Michael D Greicius

bioRxiv· June 2025

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Integration of transcriptomics and long-read genomics prioritizes structural variants in rare disease.
Tanner D Jensen, Bohan Ni, Chloe M Reuter, John E Gorzynski, Sarah Fazal, Michael D Greicius

Genome Res· April 2025

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A Quantitative Trait Locus for Reduced Microglial Expression Associates with Reduced Cerebral Amyloid Angiopathy.
Michael E Belloy, Jonathan Graff-Radford, Michael D Greicius

medRxiv· March 2025

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Plasma Aβ/Aβ is sensitive to early cerebral amyloid accumulation and predicts risk of cognitive decline across the Alzheimer's disease spectrum.
Alexandra N Trelle, Christina B Young, Hillary Vossler, Javier Ramos Benitez, Karly A Cody, Michael D Greicius

Alzheimers Dement· February 2025

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Rare genetic associations with human lifespan in UK Biobank are enriched for oncogenic genes.
Junyoung Park, Andrés Peña-Tauber, Lia Talozzi, Michael D Greicius, Yann Le Guen

Nat Commun· February 2025

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regionalpcs improve discovery of DNA methylation associations with complex traits.
Tiffany Eulalio, Min Woo Sun, Olivier Gevaert, Michael D Greicius, Thomas J Montine

Nat Commun· January 2025

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Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease.
Daniel Western, Jigyasha Timsina, Lihua Wang, Ciyang Wang, Chengran Yang, Michael D Greicius

Nat Genet· December 2024

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Role of the X Chromosome in Alzheimer Disease Genetics.
Michael E Belloy, Yann Le Guen, Ilaria Stewart, Kennedy Williams, Joachim Herz, Michael D Greicius

JAMA Neurol· October 2024

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APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer's Disease.
J Nicholas Cochran, Michael D Greicius, Alison M Goate

N Engl J Med· October 2024

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Author Correction: Rare genetic coding variants associated with human longevity and protection against age-related diseases.
Jhih-Rong Lin, Patrick Sin-Chan, Valerio Napolioni, Guillermo G Torres, Joydeep Mitra, Michael D Greicius

Nat Aging· September 2024

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Genetic associations with human longevity are enriched for oncogenic genes.
Junyoung Park, Andrés Peña-Tauber, Lia Talozzi, Michael D Greicius, Yann Le Guen

medRxiv· August 2024

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Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study.
Jie Pan, Jaume Fores-Martos, Claire Delpirou Nouh, Tanner D Jensen, Kristen Vallejo, Michael D Greicius

Acta Neuropathol Commun· August 2024

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Temporal tau asymmetry spectrum influences divergent behavior and language patterns in Alzheimer's disease.
Kyan Younes, Viktorija Smith, Emily Johns, Mackenzie L Carlson, Joseph Winer, Michael D Greicius

Brain Behav Immun· July 2024

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Plasma proteomics in the UK Biobank reveals youthful brains and immune systems promote healthspan and longevity.
Hamilton Se-Hwee Oh, Yann Le Guen, Nimrod Rappoport, Deniz Yagmur Urey, Jarod Rutledge, Michael D Greicius

bioRxiv· June 2024

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TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models.
Edward N Wilson, Congcong Wang, Michelle S Swarovski, Kristy A Zera, Hannah E Ennerfelt, Michael D Greicius

Nat Neurosci· May 2024

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: improved discovery of DNA methylation associations with complex traits.
Tiffany Eulalio, Min Woo Sun, Olivier Gevaert, Michael D Greicius, Thomas J Montine

bioRxiv· May 2024

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The Role of X Chromosome in Alzheimer's Disease Genetics.
Michael E Belloy, Yann Le Guen, Ilaria Stewart, Joachim Herz, Richard Sherva, Michael D Greicius

medRxiv· April 2024

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Integration of transcriptomics and long-read genomics prioritizes structural variants in rare disease.
Tanner D Jensen, Bohan Ni, Chloe M Reuter, John E Gorzynski, Sarah Fazal, Michael D Greicius

medRxiv· March 2024

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A 3'UTR Insertion Is a Candidate Causal Variant at the Locus Associated With Increased Risk for FTLD-TDP.
Augustine Chemparathy, Yann Le Guen, Yi Zeng, John Gorzynski, Tanner D Jensen, Michael D Greicius

Neurol Genet· February 2024

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