Publications by authors named "Michael Hottiger"

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From Bench to Clinic: The 2024 FASEB Scientific Research Conference on NAD Metabolism and Signaling.
Shin-Ichiro Imai, Eija Pirinen, Michael N Sack, Jonas T Treebak, Charalampos Tzoulis, Michael O Hottiger

Mol Med· October 2025

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MacroD1 sustains mitochondrial integrity and oxidative metabolism.
Ann-Katrin Hopp, Lorenza P Ferretti, Lisa Schlicker, Amalia Ruiz-Serrano, Udo Hetzel, Michael O Hottiger

Nat Commun· August 2025

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DNA Methyltransferase Inhibition Upregulates the Costimulatory Molecule ICAM-1 and the Immunogenic Phenotype of Melanoma Cells.
Alessandra S P Cereghetti, Patrick Turko, Phil Cheng, Stephan Benke, Ala'a Al Hrout, Michael O Hottiger

JID Innov· March 2025

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Unleashing viral mimicry: A combinatorial strategy to enhance the efficacy of PARP7 inhibitors.
Patrick Manetsch, Michael O Hottiger

Bioessays· February 2025

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Expanding the Perspective on PARP1 and Its Inhibitors in Cancer Therapy: From DNA Damage Repair to Immunomodulation.
Flurina Böhi, Michael O Hottiger

Biomedicines· July 2024

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PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency.
Meneka Rupasinghe, Cristiana Bersaglieri, Deena M Leslie Pedrioli, Patrick Ga Pedrioli, Martina Panatta, Michael O Hottiger

EMBO Rep· March 2024

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Shigella induces stress granule formation by ADP-riboxanation of the eIF3 complex.
Qinxin Zhang, Wei Xian, Zilin Li, Qian Lu, Xindi Chen, Michael O Hottiger

Cell Rep· February 2024

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Covalent PARylation of DNA base excision repair proteins regulates DNA demethylation.
Simon D Schwarz, Jianming Xu, Kapila Gunasekera, David Schürmann, Cathrine B Vågbø, Michael O Hottiger

Nat Commun· January 2024

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Combinatorial Treatment with PARP and MAPK Inhibitors Overcomes Phenotype Switch-Driven Drug Resistance in Advanced Melanoma.
Lorenza P Ferretti, Flurina Böhi, Deena M Leslie Pedrioli, Phil F Cheng, Elena Ferrari, Michael O Hottiger

Cancer Res· December 2023

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PARP7-mediated ADP-ribosylation of FRA1 promotes cancer cell growth by repressing IRF1- and IRF3-dependent apoptosis.
Patrick Manetsch, Flurina Böhi, Kathrin Nowak, Deena M Leslie Pedrioli, Michael O Hottiger

Proc Natl Acad Sci U S A· December 2023

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Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels.
Anka Güldenpfennig, Ann-Katrin Hopp, Lukas Muskalla, Patrick Manetsch, Fabio Raith, Michael O Hottiger

Nucleic Acids Res· September 2023

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Poly(ADP-Ribose) Polymerase-1 Lacking Enzymatic Activity Is Not Compatible with Mouse Development.
Tatiana Kamaletdinova, Wen Zong, Pavel Urbánek, Sijia Wang, Mara Sannai, Michael O Hottiger

Cells· August 2023

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Altered cytoplasmic and nuclear ADP-ribosylation levels analyzed with an improved ADP-ribose binder are a prognostic factor in renal cell carcinoma.
Peter Schraml, Fabio Aimi, Martin Zoche, Domingo Aguilera-Garcia, Fabian Arnold, Michael O Hottiger

J Pathol Clin Res· July 2023

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ADP-ribosyltransferases, an update on function and nomenclature.
Bernhard Lüscher, Ivan Ahel, Matthias Altmeyer, Alan Ashworth, Peter Bai, Michael O Hottiger

FEBS J· December 2022

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Subcellular Quantitation of ADP-Ribosylation by High-Content Microscopy.
Lukas Muskalla, Anka Güldenpfennig, Michael O Hottiger

Methods Mol Biol· December 2022

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Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death.
Lin Liu, Jarrod J Sandow, Deena M Leslie Pedrioli, Andre L Samson, Natasha Silke, Michael O Hottiger

Sci Adv· May 2022

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A Novel Spectral Annotation Strategy Streamlines Reporting of Mono-ADP-ribosylated Peptides Derived from Mouse Liver and Spleen in Response to IFN-γ.
Shiori Kuraoka, Hideyuki Higashi, Yoshihiro Yanagihara, Abhijeet R Sonawane, Shin Mukai, Michael O Hottiger

Mol Cell Proteomics· April 2022

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Identification of the Mouse T Cell ADP-Ribosylome Uncovers ARTC2.2 Mediated Regulation of CD73 by ADP-Ribosylation.
Mario Leutert, Yinghui Duan, Riekje Winzer, Stephan Menzel, Eva Tolosa, Michael O Hottiger

Front Immunol· December 2021

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Interplay between ADP-ribosyltransferases and essential cell signaling pathways controls cellular responses.
Flurina Boehi, Patrick Manetsch, Michael O Hottiger

Cell Discov· November 2021

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Cytoplasmic ADP-ribosylation levels correlate with markers of patient outcome in distinct human cancers.
Fabio Aimi, Holger Moch, Peter Schraml, Michael O Hottiger

Mod Pathol· August 2021

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Investigation of Mitochondrial ADP-Ribosylation Via Immunofluorescence.
Ann-Katrin Hopp, Michael O Hottiger

Methods Mol Biol· July 2021

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Establishment of a Mass-Spectrometry-Based Method for the Identification of the Whole Blood and Plasma ADP-Ribosylomes.
Stephanie C Lüthi, Anna Howald, Kathrin Nowak, Robert Graage, Giody Bartolomei, Michael O Hottiger

J Proteome Res· June 2021

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MyoD induces ARTD1 and nucleoplasmic poly-ADP-ribosylation during fibroblast to myoblast transdifferentiation.
Lavinia Bisceglie, Ann-Katrin Hopp, Kapila Gunasekera, Roni H Wright, François Le Dily, Michael O Hottiger

iScience· May 2021

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Uncovering the Invisible: Mono-ADP-ribosylation Moved into the Spotlight.
Ann-Katrin Hopp, Michael O Hottiger

Cells· March 2021

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Mitochondrial NAD Controls Nuclear ARTD1-Induced ADP-Ribosylation.
Ann-Katrin Hopp, Federico Teloni, Lavinia Bisceglie, Corentin Gondrand, Fabio Raith, Michael O Hottiger

Mol Cell· January 2021

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