Publications by authors named "Michael Hough"

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Double crossed? Structural and computational studies of an unusually crosslinked haem in cytochrome P460.
Hans E Pfalzgraf, Aditya G Rao, Kakali Sen, Hannah R Adams, Marcus Edwards, Michael A Hough

Chem Sci· September 2025

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Time-resolved serial synchrotron and serial femtosecond crystallography of heme proteins using photocaged nitric oxide.
Peter Smyth, Sofia Jaho, Lewis J Williams, Gabriel Karras, Ann Fitzpatrick, Michael A Hough

IUCrJ· September 2025

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Enhanced intensity-based clustering of isomorphous multi-crystal data sets in the presence of subtle variations.
Amy J Thompson, James Beilsten-Edmands, Cicely Tam, Juan Sanchez-Weatherby, James Sandy, Michael A Hough

Acta Crystallogr D Struct Biol· June 2025

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Does crossing the pond affect crystal quality?
Christopher S Campomizzi, M Elizabeth Snell, Halina Mikolajek, James Sandy, Juan Sanchez-Weatherby, Michael A Hough

bioRxiv· June 2025

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Damage before destruction? X-ray-induced changes in single-pulse serial femtosecond crystallography.
Lewis J Williams, Amy J Thompson, Philipp Dijkstal, Martin Appleby, Greta Assmann, Michael A Hough

IUCrJ· May 2025

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Cytochromes P460 and c'-β: exploiting a novel fold for multiple functions.
Hannah R Adams, Sotaro Fujii, Hans E Pfalzgraf, Peter Smyth, Colin R Andrew, Michael A Hough

J Biol Inorg Chem· March 2025

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Use of fixed targets for serial crystallography.
Sofia Jaho, Danny Axford, Do-Heon Gu, Michael A Hough, Robin L Owen

Methods Enzymol· November 2024

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Spectroscopically Validated pH-dependent MSOX Movies Provide Detailed Mechanism of Copper Nitrite Reductases.
Samuel L Rose, Felix Martín Ferroni, Sam Horrell, Carlos Dante Brondino, Robert R Eady, Michael A Hough

J Mol Biol· September 2024

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Conformational rigidity of cytochrome c'-α from a thermophile is associated with slow NO binding.
Sotaro Fujii, Michael T Wilson, Hannah R Adams, Halina Mikolajek, Dimitri A Svistunenko, Michael A Hough

Biophys J· August 2024

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Efficient in situ screening of and data collection from microcrystals in crystallization plates.
Amy J Thompson, Juan Sanchez-Weatherby, Lewis J Williams, Halina Mikolajek, James Sandy, Michael A Hough

Acta Crystallogr D Struct Biol· April 2024

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A redox switch allows binding of Fe(II) and Fe(III) ions in the cyanobacterial iron-binding protein FutA from .
Rachel Bolton, Moritz M Machelett, Jack Stubbs, Danny Axford, Nicolas Caramello, Michael A Hough

Proc Natl Acad Sci U S A· March 2024

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Crystallization and In Situ Room Temperature Data Collection Using the Crystallization Facility at Harwell and Beamline VMXi, Diamond Light Source.
James Sandy, Halina Mikolajek, Amy J Thompson, Juan Sanchez-Weatherby, Michael A Hough

J Vis Exp· March 2024

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Beyond the coupled distortion model: structural analysis of the single domain cupredoxin AcoP, a green mononuclear copper centre with original features.
Magali Roger, Philippe Leone, Ninian J Blackburn, Sam Horrell, Tadeo Moreno Chicano, Michael A Hough

Dalton Trans· January 2024

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New insights into controlling radical migration pathways in heme enzymes gained from the study of a dye-decolorising peroxidase.
Marina Lučić, Michael T Wilson, Jacob Pullin, Michael A Hough, Dimitri A Svistunenko

Chem Sci· November 2023

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Protein-to-structure pipeline for ambient-temperature in situ crystallography at VMXi.
Halina Mikolajek, Juan Sanchez-Weatherby, James Sandy, Richard J Gildea, Ivan Campeotto, Michael A Hough

IUCrJ· July 2023

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A heme pocket aromatic quadrupole modulates gas binding to cytochrome c'-β: Implications for NO sensors.
Hannah R Adams, Dimitri A Svistunenko, Michael T Wilson, Sotaro Fujii, Richard W Strange, Michael A Hough

J Biol Chem· June 2023

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The CCP4 suite: integrative software for macromolecular crystallography.
Jon Agirre, Mihaela Atanasova, Haroldas Bagdonas, Charles B Ballard, Arnaud Baslé, Michael A Hough

Acta Crystallogr D Struct Biol· June 2023

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Perspective: Structure determination of protein-ligand complexes at room temperature using X-ray diffraction approaches.
Michael A Hough, Filippo Prischi, Jonathan A R Worrall

Front Mol Biosci· January 2023

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Serial femtosecond crystallography approaches to understanding catalysis in iron enzymes.
Jonathan A R Worrall, Michael A Hough

Curr Opin Struct Biol· December 2022

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Serial Femtosecond Crystallography Reveals the Role of Water in the One- or Two-Electron Redox Chemistry of Compound I in the Catalytic Cycle of the B-Type Dye-Decolorizing Peroxidase DtpB.
Marina Lučić, Michael T Wilson, Takehiko Tosha, Hiroshi Sugimoto, Anastasya Shilova, Michael A Hough

ACS Catal· November 2022

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Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature.
Tadeo Moreno-Chicano, Leiah M Carey, Danny Axford, John H Beale, R Bruce Doak, Michael A Hough

IUCrJ· September 2022

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Crystal structure of thermally stable homodimeric cytochrome c'-β from Thermus thermophilus.
Taisuke Yoshimi, Sotaro Fujii, Hiroya Oki, Takeshi Igawa, Hannah R Adams, Michael A Hough

Acta Crystallogr F Struct Biol Commun· June 2022

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Serial synchrotron and XFEL crystallography for studies of metalloprotein catalysis.
Michael A Hough, Robin L Owen

Curr Opin Struct Biol· December 2021

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Aspartate or arginine? Validated redox state X-ray structures elucidate mechanistic subtleties of Fe = O formation in bacterial dye-decolorizing peroxidases.
Marina Lučić, Michael T Wilson, Dimitri A Svistunenko, Robin L Owen, Michael A Hough

J Biol Inorg Chem· October 2021

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Differential protein expression during growth on model and commercial mixtures of naphthenic acids in Pseudomonas fluorescens Pf-5.
Boyd A McKew, Richard Johnson, Lindsay Clothier, Karl Skeels, Matthew S Ross, Michael A Hough

Microbiologyopen· August 2021

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