Publications by authors named "Michael Storek"

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First-in-human study with SAR445088: A novel selective classical complement pathway inhibitor.
Timothy Chow, Pirouz Shamszad, Christopher Vinnard, Esther Yoon, Julia Belinski, Irene Karpenko, Laurent Perrin, Kristen Auwarter, Michael Storek, Howard Surks

Clin Transl Sci· April 2023

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Bruton tyrosine kinase modulates systemic immune activation to bacterial translocation in primary antibody deficiencies.
Hsi-En Ho, Lin Radigan, Jingjing Qi, Vladimir Roudko, Michael J Storek

J Allergy Clin Immunol· December 2025

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Confirmation of Fixed Quarterly Riliprubart Regimen in Patients with Cold Agglutinin Disease Using Population PK/PD and Exposure-Response Analyses.
Timothy Chow, Marek Wardecki, Michael Storek, Nancy Wong

Clin Pharmacol Ther· August 2025

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Selective Btk inhibition by PRN1008/PRN473 blocks human CLEC-2, and PRN473 reduces venous thrombosis formation in mice.
Christopher W Smith, Joana Campos, Helena C Brown, Natalie J Jooss, Vanesa-Sindi Ivanova, Michael Storek

Blood Adv· November 2024

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Long-term efficacy and safety of continued complement C1s inhibition with sutimlimab in cold agglutinin disease: CADENZA study Part B.
Alexander Röth, Sigbjørn Berentsen, Wilma Barcellini, Shirley D'Sa, Bernd Jilma, Michael Storek

EClinicalMedicine· August 2024

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C1s targeting antibodies inhibit the growth of cutaneous squamous carcinoma cells.
Liisa Nissinen, Pilvi Riihilä, Kristina Viiklepp, Vaishnavi Rajagopal, Michael J Storek

Sci Rep· June 2024

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C3d-Targeted factor H inhibits tissue complement in disease models and reduces glomerular injury without affecting circulating complement.
Fei Liu, Sarah T Ryan, Kelly C Fahnoe, Jennifer G Morgan, Anne E Cheung, Michael J Storek

Mol Ther· April 2024

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Safety, tolerability, and activity of the active C1s antibody riliprubart in cold agglutinin disease: a phase 1b study.
Shirley D'Sa, Josephine M I Vos, Wilma Barcellini, Marek Wardęcki, Laurent Perrin, Michael Storek

Blood· February 2024

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SAR443809: a selective inhibitor of the complement alternative pathway, targeting complement factor Bb.
Vaishnavi Rajagopal, Nina Leksa, Ronald Gorham, Siddharth Jindal, Soumya Nair, Michael Storek

Blood Adv· August 2023

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Anti-C1s humanized monoclonal antibody SAR445088: A classical pathway complement inhibitor specific for the active form of C1s.
Ken T Simmons, Joanne Chan, Sami Hussain, Eileen L Rose, Kate Markham, Michael Storek

Clin Immunol· June 2023

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Sutimlimab in patients with cold agglutinin disease: results of the randomized placebo-controlled phase 3 CADENZA trial.
Alexander Röth, Sigbjørn Berentsen, Wilma Barcellini, Shirley D'Sa, Bernd Jilma, Michael Storek

Blood· September 2022

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Development and Optimization of Bifunctional Fusion Proteins to Locally Modulate Complement Activation in Diseased Tissue.
Kelly C Fahnoe, Fei Liu, Jennifer G Morgan, Sarah T Ryan, Michael Storek

Front Immunol· July 2022

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Classical Complement Pathway Inhibition in a "Human-On-A-Chip" Model of Autoimmune Demyelinating Neuropathies.
John W Rumsey, Case Lorance, Max Jackson, Trevor Sasserath, Christopher W McAleer, Michael J Storek

Adv Ther (Weinh)· June 2022

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The human complement receptor type 2 (CR2)/CR1 fusion protein TT32, a novel targeted inhibitor of the classical and alternative pathway C3 convertases, prevents arthritis in active immunization and passive transfer mouse models.
Masha Fridkis-Hareli, Michael Storek, Eran Or, Richard Altman, Suresh Katti

Mol Immunol· January 2019

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Global View on Rare Diseases: A Mini Review.
Blanka Klimova, Michael Storek, Martin Valis, Kamil Kuca

Curr Med Chem· November 2017

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Positive and Negative Mixed Glass Former Effects in Sodium Borosilicate and Borophosphate Glasses Studied by (23)Na NMR.
Michael Storek, Mischa Adjei-Acheamfour, Randilynn Christensen, Steve W Martin, Roland Böhmer

J Phys Chem B· May 2016

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Local-field approximation of homonuclear dipolar interactions in ⁷Li-NMR: density-matrix calculations and random-walk simulations tested by echo experiments on borate glasses.
Michael Storek, Kenneth R Jeffrey, Roland Böhmer

Solid State Nucl Magn Reson· March 2015

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Synthesis of cyclic pyranopterin monophosphate, a biosynthetic intermediate in the molybdenum cofactor pathway.
Keith Clinch, Derek K Watt, Rachel A Dixon, Sylvia M Baars, Graeme J Gainsford, Michael Storek

J Med Chem· February 2013

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NMR and conductivity studies of the mixed glass former effect in lithium borophosphate glasses.
Michael Storek, Roland Böhmer, Steve W Martin, Dirk Larink, Hellmut Eckert

J Chem Phys· September 2012

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Solution structure of TT30, a novel complement therapeutic agent, provides insight into its joint binding to complement C3b and C3d.
Keying Li, Jayesh Gor, V Michael Holers, Michael J Storek, Stephen J Perkins

J Mol Biol· May 2012

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Design and development of TT30, a novel C3d-targeted C3/C5 convertase inhibitor for treatment of human complement alternative pathway-mediated diseases.
Masha Fridkis-Hareli, Michael Storek, Istvan Mazsaroff, Antonio M Risitano, Ante S Lundberg

Blood· October 2011

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Anti-tumor effect of CT-322 as an adnectin inhibitor of vascular endothelial growth factor receptor-2.
Roni Mamluk, Irvith M Carvajal, Brent A Morse, Henry Wong, Janette Abramowitz, Michael J Storek

MAbs· July 2011

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Delineation of the complement receptor type 2-C3d complex by site-directed mutagenesis and molecular docking.
Craig D Shaw, Michael J Storek, Kendra A Young, James M Kovacs, Joshua M Thurman

J Mol Biol· December 2010

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Dicamba monooxygenase: structural insights into a dynamic Rieske oxygenase that catalyzes an exocyclic monooxygenation.
Robert L D'Ordine, Timothy J Rydel, Michael J Storek, Eric J Sturman, Farhad Moshiri

J Mol Biol· September 2009

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5-amino-2'-deoxyuridine, a novel thymidine analogue for high-resolution footprinting of protein-DNA complexes.
Michael J Storek, Alexandru Suciu, Gregory L Verdine

Org Lett· October 2002

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