Publications by authors named "Michelle Dunstone"

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CD59, Disulphide-Locked Human C9 and Horse C9 Inhibit Human Membrane Attack Complex Assembly by Similar Mechanisms.
Rebekah S Cooke, Bradley A Spicer, Richard A Harrison, Michelle A Dunstone, B Paul Morgan

Immunology· November 2025

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Action of the Terminal Complement Pathway on Cell Membranes.
Bill H T Ho, Bradley A Spicer, Michelle A Dunstone

J Membr Biol· August 2025

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The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9.
Charles Bayly-Jones, Bill H T Ho, Corinna Lau, Eleanor W W Leung, Laura D'Andrea, Michelle A Dunstone

Commun Biol· January 2023

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Single-molecule analysis of the entire perfringolysin O pore formation pathway.
Conall McGuinness, James C Walsh, Charles Bayly-Jones, Michelle A Dunstone, Michelle P Christie

Elife· August 2022

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Branching out the aerolysin, ETX/MTX-2 and Toxin_10 family of pore forming proteins.
Chris J Lacomel, Michelle A Dunstone, Bradley A Spicer

J Invertebr Pathol· November 2021

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Ancient but Not Forgotten: New Insights Into MPEG1, a Macrophage Perforin-Like Immune Effector.
Charles Bayly-Jones, Siew Siew Pang, Bradley A Spicer, James C Whisstock, Michelle A Dunstone

Front Immunol· June 2021

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Going full circle: Determining the structures of complement component 9.
Bradley A Spicer, Michelle A Dunstone

Methods Enzymol· June 2021

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Three-Dimensional Chemical Mapping of a Single Protein in the Hydrated State with Atom Probe Tomography.
Shi Qiu, Changxi Zheng, Vivek Garg, Yu Chen, Gediminas Gervinskas, Michelle A Dunstone

Anal Chem· April 2020

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The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1.
Siew Siew Pang, Charles Bayly-Jones, Mazdak Radjainia, Bradley A Spicer, Ruby H P Law, Michelle A Dunstone

Nat Commun· September 2019

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Evaluation of Serum Glycoprotein Biomarker Candidates for Detection of Esophageal Adenocarcinoma and Surveillance of Barrett's Esophagus.
Alok K Shah, Gunter Hartel, Ian Brown, Clay Winterford, Renhua Na, Michelle A Dunstone

Mol Cell Proteomics· December 2018

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The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Bradley A Spicer, Ruby H P Law, Tom T Caradoc-Davies, Sue M Ekkel, Charles Bayly-Jones, Michelle A Dunstone

Nat Commun· August 2018

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The emerging role of pore forming proteins in cell biology and development.
Michelle A Dunstone

Semin Cell Dev Biol· December 2017

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Cryo-electron tomography: an ideal method to study membrane-associated proteins.
Michelle A Dunstone, Alex de Marco

Philos Trans R Soc Lond B Biol Sci· August 2017

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The mystery behind membrane insertion: a review of the complement membrane attack complex.
Charles Bayly-Jones, Doryen Bubeck, Michelle A Dunstone

Philos Trans R Soc Lond B Biol Sci· August 2017

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Real-time visualization of perforin nanopore assembly.
Carl Leung, Adrian W Hodel, Amelia J Brennan, Natalya Lukoyanova, Sharon Tran, Michelle A Dunstone

Nat Nanotechnol· May 2017

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Giant MACPF/CDC pore forming toxins: A class of their own.
Cyril F Reboul, James C Whisstock, Michelle A Dunstone

Biochim Biophys Acta· March 2016

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Structure of the poly-C9 component of the complement membrane attack complex.
Natalya V Dudkina, Bradley A Spicer, Cyril F Reboul, Paul J Conroy, Natalya Lukoyanova, Michelle A Dunstone

Nat Commun· February 2016

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Stonefish toxin defines an ancient branch of the perforin-like superfamily.
Andrew M Ellisdon, Cyril F Reboul, Santosh Panjikar, Kitmun Huynh, Christine A Oellig, Michelle A Dunstone

Proc Natl Acad Sci U S A· December 2015

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Conformational changes during pore formation by the perforin-related protein pleurotolysin.
Natalya Lukoyanova, Stephanie C Kondos, Irene Farabella, Ruby H P Law, Cyril F Reboul, Michelle A Dunstone

PLoS Biol· February 2015

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Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin.
Carl Leung, Natalya V Dudkina, Natalya Lukoyanova, Adrian W Hodel, Irene Farabella, Michelle A Dunstone

Elife· December 2014

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The cellular redox environment alters antigen presentation.
Jonathan A Trujillo, Nathan P Croft, Nadine L Dudek, Rudragouda Channappanavar, Alex Theodossis, Michelle A Dunstone

J Biol Chem· October 2014

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A new model for pore formation by cholesterol-dependent cytolysins.
Cyril F Reboul, James C Whisstock, Michelle A Dunstone

PLoS Comput Biol· August 2014

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The perforin pore facilitates the delivery of cationic cargos.
Sarah E Stewart, Stephanie C Kondos, Antony Y Matthews, Michael E D'Angelo, Michelle A Dunstone

J Biol Chem· March 2014

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Structural biology: Torqueing about pores.
James C Whisstock, Michelle A Dunstone

Nat Chem Biol· October 2013

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Screening of 71 P. multocida proteins for protective efficacy in a fowl cholera infection model and characterization of the protective antigen PlpE.
Tamás Hatfaludi, Keith Al-Hasani, Lan Gong, John D Boyce, Mark Ford, Michelle A Dunstone

PLoS One· March 2013

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