Publications by authors named "Nancy Benkusky"

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Genome-wide analyses of gene expression profile identify key genes and pathways involved in skeletal response to phosphate and 1,25-dihydroxyvitamin D in vivo.
Seong Min Lee, Mark B Meyer, Nancy A Benkusky, J Wesley Pike

J Steroid Biochem Mol Biol· September 2023

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A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis.
Sung-Hee Yoon, Mark B Meyer, Carlos Arevalo, Murat Tekguc, Chengcheng Zhang, Nancy A Benkusky

J Clin Invest· May 2023

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Rapid genomic changes by mineralotropic hormones and kinase SIK inhibition drive coordinated renal Cyp27b1 and Cyp24a1 expression via CREB modules.
Mark B Meyer, Nancy A Benkusky, Seong Min Lee, Sung-Hee Yoon, Michael Mannstadt

J Biol Chem· November 2022

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Deletion of a putative promoter-proximal Tnfsf11 regulatory region in mice does not alter bone mass or Tnfsf11 expression in vivo.
Ryan S MacLeod, Mark B Meyer, Jinhu Xiong, Keisha M Cawley, Yu Liu, Nancy A Benkusky

PLoS One· November 2021

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Genomic Mechanisms Governing Mineral Homeostasis and the Regulation and Maintenance of Vitamin D Metabolism.
J Wesley Pike, Seong Min Lee, Nancy A Benkusky, Mark B Meyer

JBMR Plus· January 2021

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A Control Region Near the Fibroblast Growth Factor 23 Gene Mediates Response to Phosphate, 1,25(OH)2D3, and LPS In Vivo.
Seong Min Lee, Alex H Carlson, Melda Onal, Nancy A Benkusky, Mark B Meyer

Endocrinology· December 2019

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A chromatin-based mechanism controls differential regulation of the cytochrome P450 gene in renal and non-renal tissues.
Mark B Meyer, Seong Min Lee, Alex H Carlson, Nancy A Benkusky, Martin Kaufmann

J Biol Chem· September 2019

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Targeted genomic deletions identify diverse enhancer functions and generate a kidney-specific, endocrine-deficient pseudo-null mouse.
Mark B Meyer, Nancy A Benkusky, Martin Kaufmann, Seong Min Lee, Robert R Redfield

J Biol Chem· June 2019

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The Phosphorylated Estrogen Receptor α (ER) Cistrome Identifies a Subset of Active Enhancers Enriched for Direct ER-DNA Binding and the Transcription Factor GRHL2.
Kyle T Helzer, Mary Szatkowski Ozers, Mark B Meyer, Nancy A Benkusky, Natalia Solodin

Mol Cell Biol· February 2019

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The impact of VDR expression and regulation in vivo.
Seong Min Lee, Mark B Meyer, Nancy A Benkusky, Charles A O'Brien, J Wesley Pike

J Steroid Biochem Mol Biol· March 2018

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A Novel Distal Enhancer Mediates Inflammation-, PTH-, and Early Onset Murine Kidney Disease-Induced Expression of the Mouse Gene.
Melda Onal, Alex H Carlson, Jeff D Thostenson, Nancy A Benkusky, Mark B Meyer

JBMR Plus· January 2018

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A kidney-specific genetic control module in mice governs endocrine regulation of the cytochrome P450 gene essential for vitamin D activation.
Mark B Meyer, Nancy A Benkusky, Martin Kaufmann, Seong Min Lee, Melda Onal

J Biol Chem· October 2017

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The vitamin D receptor: contemporary genomic approaches reveal new basic and translational insights.
J Wesley Pike, Mark B Meyer, Seong-Min Lee, Melda Onal, Nancy A Benkusky

J Clin Invest· April 2017

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Genomic Determinants of Vitamin D-Regulated Gene Expression.
J Wesley Pike, Mark B Meyer, Nancy A Benkusky, Seong Min Lee, Hillary St John

Vitam Horm· January 2017

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Selective regulation of Mmp13 by 1,25(OH)D, PTH, and Osterix through distal enhancers.
Mark B Meyer, Nancy A Benkusky, Melda Onal, J Wesley Pike

J Steroid Biochem Mol Biol· November 2016

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Epigenetic Plasticity Drives Adipogenic and Osteogenic Differentiation of Marrow-derived Mesenchymal Stem Cells.
Mark B Meyer, Nancy A Benkusky, Buer Sen, Janet Rubin, J Wesley Pike

J Biol Chem· August 2016

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Epigenetic histone modifications and master regulators as determinants of context dependent nuclear receptor activity in bone cells.
J Wesley Pike, Mark B Meyer, Hillary C St John, Nancy A Benkusky

Bone· December 2015

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Mechanisms of Enhancer-mediated Hormonal Control of Vitamin D Receptor Gene Expression in Target Cells.
Seong Min Lee, Mark B Meyer, Nancy A Benkusky, Charles A O'Brien, J Wesley Pike

J Biol Chem· December 2015

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1,25-Dihydroxyvitamin D3 Controls a Cohort of Vitamin D Receptor Target Genes in the Proximal Intestine That Is Enriched for Calcium-regulating Components.
Seong Min Lee, Erin M Riley, Mark B Meyer, Nancy A Benkusky, Lori A Plum

J Biol Chem· July 2015

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Profiling histone modifications by chromatin immunoprecipitation coupled to deep sequencing in skeletal cells.
Mark B Meyer, Nancy A Benkusky, J Wesley Pike

Methods Mol Biol· June 2015

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Selective Distal Enhancer Control of the Mmp13 Gene Identified through Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Genomic Deletions.
Mark B Meyer, Nancy A Benkusky, J Wesley Pike

J Biol Chem· April 2015

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The parathyroid hormone-regulated transcriptome in osteocytes: parallel actions with 1,25-dihydroxyvitamin D3 to oppose gene expression changes during differentiation and to promote mature cell function.
Hillary C St John, Mark B Meyer, Nancy A Benkusky, Alex H Carlson, Mathew Prideaux

Bone· March 2015

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The osteoblast to osteocyte transition: epigenetic changes and response to the vitamin D3 hormone.
Hillary C St John, Kathleen A Bishop, Mark B Meyer, Nancy A Benkusky, Ning Leng

Mol Endocrinol· July 2014

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Genomic determinants of gene regulation by 1,25-dihydroxyvitamin D3 during osteoblast-lineage cell differentiation.
Mark B Meyer, Nancy A Benkusky, Chang-Hun Lee, J Wesley Pike

J Biol Chem· July 2014

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The RUNX2 cistrome in osteoblasts: characterization, down-regulation following differentiation, and relationship to gene expression.
Mark B Meyer, Nancy A Benkusky, J Wesley Pike

J Biol Chem· June 2014

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