Publications by authors named "Nicholas D Huntington"

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A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity.
Shuwei Liang, Eric Tran, Xin Du, Jiajun Dong, Harrison Sudholz, Hao Chen, Zihan Qu, Nicholas D Huntington, Jeffrey J Babon, Nadia J Kershaw

Nat Commun· July 2023

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Enhancing anti-tumor immunity of natural killer cells through targeting IL-15R signaling.
Iva Nikolic, Joseph Cursons, Benjamin Shields, Stephane Chappaz, Harrison Sudholz, Nicholas D Huntington

Cancer Cell· November 2025

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Lymph-node-derived stem-like but not tumor-tissue-resident CD8 T cells fuel anticancer immunity.
Sharanya K M Wijesinghe, Lisa Rausch, Sarah S Gabriel, Giovanni Galletti, Marco De Luca, Nicholas D Huntington

Nat Immunol· August 2025

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Core fucosylation of IL-2RB is required for natural killer cell homeostasis.
Harrison Sudholz, Xiangpeng Meng, Hae-Young Park, Zihan Shen, Iva Nikolic, Nicholas D Huntington

Cell Rep· August 2025

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Adjusting the scope of natural killer cells in cancer therapy.
Zihen Shen, Xiangpeng Meng, Jai Rautela, Michael Chopin, Nicholas D Huntington

Cell Mol Immunol· July 2025

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Rescuing natural killer cells from the cancer wilderness.
Nicholas D Huntington

J Immunother Cancer· May 2025

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Emerging Role of the p53 Pathway in Modulating NK Cell-Mediated Immunity.
Yu-Chi Chen, Christopher G Bazewicz, Saketh S Dinavahi, Nicholas D Huntington, Todd D Schell

Mol Cancer Ther· April 2025

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Soluble CD52 mediates immune suppression by human seminal fluid.
Leonard C Harrison, Natalie L Stone, Esther Bandala-Sanchez, Nicholas D Huntington, Robert I McLachlan

Front Immunol· December 2024

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Context-restricted PD-(L)1 checkpoint agonism by CTLA4-Ig therapies inhibits T cell activity.
Ethan P Oxley, Nadia J Kershaw, Cynthia Louis, Katharine J Goodall, Maximilian M Garwood, Nicholas D Huntington

Cell Rep· October 2024

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When playing the NK cell therapy card in glioblastoma, you can't beat interleukin-21.
Nicholas D Huntington

Cancer Cell· August 2024

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DOT1L maintains NK cell phenotype and function for optimal tumor control.
Harrison Sudholz, Iona S Schuster, Momeneh Foroutan, Xavier Sng, Christopher E Andoniou, Nicholas D Huntington

Cell Rep· June 2024

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Author Correction: Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cell.
Yulong Gao, Fernando Souza-Fonseca-Guimaraes, Tobias Bald, Susanna S Ng, Arabella Young, Nicholas D Huntington

Nat Immunol· May 2024

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Optimisation of a primary human CAR-NK cell manufacturing pipeline.
Aline Pfefferle, Julian Contet, Kahlia Wong, Charlotte Chen, Els Verhoeyen, Nicholas D Huntington

Clin Transl Immunology· May 2024

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Author Correction: CIS is a potent checkpoint in NK cell-mediated tumor immunity.
Rebecca B Delconte, Tatiana B Kolesnik, Laura F Dagley, Jai Rautela, Wei Shi, Nicholas D Huntington

Nat Immunol· February 2024

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IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development.
Wilford Goh, Harrison Sudholz, Momeneh Foroutan, Sebastian Scheer, Aline Pfefferle, Nicholas D Huntington

Nat Immunol· February 2024

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Interferon-epsilon is a novel regulator of NK cell responses in the uterus.
Jemma R Mayall, Jay C Horvat, Niamh E Mangan, Anne Chevalier, Huw McCarthy, Nicholas D Huntington

EMBO Mol Med· February 2024

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CD45 limits early Natural Killer cell development.
Lizeth G Meza Guzman, Craig D Hyland, Grace M Bidgood, Evelyn Leong, Zihan Shen, Nicholas D Huntington

Immunol Cell Biol· January 2024

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Small molecule. Big biology. Dual phosphatase inhibitor enters the immunotherapy fray.
Nicholas S Wilson, Nicholas D Huntington

Immunol Cell Biol· January 2024

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AP-1 transcription factors in cytotoxic lymphocyte development and antitumor immunity.
Diana Schnoegl, Angela Hiesinger, Nicholas D Huntington, Dagmar Gotthardt

Curr Opin Immunol· December 2023

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Interleukin-15 cytokine checkpoints in natural killer cell anti-tumor immunity.
Harrison Sudholz, Rebecca B Delconte, Nicholas D Huntington

Curr Opin Immunol· October 2023

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Ironman training for NK cells.
Nicholas D Huntington

Nat Immunol· October 2023

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CIS controls the functional polarization of GM-CSF-derived macrophages.
Shengbo Zhang, Jai Rautela, Naiara G Bediaga, Tatiana B Kolesnik, Yue You, Nicholas D Huntington

Cell Mol Immunol· January 2023

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TGFβ and CIS Inhibition Overcomes NK-cell Suppression to Restore Antitumor Immunity.
Fernando Souza-Fonseca-Guimaraes, Gustavo R Rossi, Laura F Dagley, Momeneh Foroutan, Timothy R McCulloch, Nicholas D Huntington

Cancer Immunol Res· September 2022

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Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy.
Ashleigh R Poh, Christopher G Love, David Chisanga, James H Steer, David Baloyan, Nicholas D Huntington

Sci Adv· June 2022

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Targeting CISH enhances natural cytotoxicity receptor signaling and reduces NK cell exhaustion to improve solid tumor immunity.
Pierre-Louis Bernard, Rebecca Delconte, Sonia Pastor, Vladimir Laletin, Cathy Costa Da Silva, Nicholas D Huntington

J Immunother Cancer· May 2022

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