Publications by authors named "Nicholas Leeper"

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Smooth muscle cells in atherosclerosis: essential but overlooked translational perspectives.
Pascal Azar, Kai-Uwe Jarr, Delphine Gomez, Helle F Jørgensen, Nicholas J Leeper

Eur Heart J· December 2025

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The atherosclerosis-cancer axis: the shared immunotherapeutic potential of CBL inhibition.
Kai-Uwe Jarr, Lingfeng Luo, Nicholas J Leeper

Eur Heart J· December 2025

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Generation of an induced pluripotent stem cell line from a patient with Varicose veins.
Chikage Noishiki, Amit Manhas, Shaunak S Adkar, Dipti Tripathi, David Wu, Nicholas J Leeper

Stem Cell Res· December 2025

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Zodasiran, an RNAi therapeutic targeting ANGPTL3, for treating patients with homozygous familial hypercholesterolaemia (GATEWAY): an open-label, randomised, phase 2 trial.
Frederick J Raal, Jean Bergeron, Daniel Gaudet, Robert S Rosenson, David R Sullivan, Nicholas J Leeper

Lancet Diabetes Endocrinol· December 2025

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PNPLA3 Inhibition and Cardiometabolic Risk: Reassessing Dyslipidemia and Atherosclerotic Cardiovascular Disease Concerns.
Shicheng Guo, Eric Garcia-Medel, Thomas Schluep, Rohit Loomba, Nicholas J Leeper

Gastroenterology· October 2025

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Response to: 'A call for patient involvement in peripheral artery disease research priority setting'.
Mary M McDermott, Daniella Kadian-Dodov, Herbert D Aronow, Joshua A Beckman, Mark A Creager, Nicholas J Leeper

Vasc Med· October 2025

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Cardiovascular disease and diagnosis of advanced prostate cancer.
Kevin T Nead, Allen M Haas, Jing Zhao, Ting Xiong, Chad Tang, Nicholas J Leeper

Cardiooncology· October 2025

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Genetic modelling of triglyceride-rich lipoprotein/remnant lowering mimics APOC3-silencing and predicts clinically relevant coronary heart disease event reductions.
Elias Björnson, Chris Packard, Martin Adiels, Nicholas J Leeper, Jennifer Hellawell

Eur J Prev Cardiol· October 2025

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Clonal haematopoiesis of indeterminate potential and mortality in coronary artery disease.
Moritz von Scheidt, Shaunak S Adkar, Johannes Krefting, Gregor Hoermann, Manja Meggendorfer, Nicholas J Leeper

Eur Heart J· September 2025

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Computational Modeling Predicts Benefits of Proefferocytic Therapy in Human Atherosclerosis.
Kai-Uwe Jarr, Kaylin C A Palm, Gerard Pasterkamp, Michal Mokry, Nicholas J Leeper

Circulation· July 2025

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Dissecting the Genetic Architecture of Intracranial Aneurysms.
Shaunak S Adkar, Julie Lynch, Ryan B Choi, Tanmoy Roychowdhury, Renae L Judy, Nicholas J Leeper

Circ Genom Precis Med· June 2025

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Research priorities for peripheral artery disease: A statement from the Society for Vascular Medicine.
Mary M McDermott, Daniella Kadian-Dodov, Herbert A Aronow, Joshua A Beckman, Demetria M Bolden, Nicholas J Leeper

Vasc Med· June 2025

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Metabolomic Profiles During and After a Hypertensive Disorder of Pregnancy: The EPOCH Study.
Mark A Hlatky, Chi-Hung Shu, Nasim Bararpour, Brenna M Murphy, Sabina M Sorondo, Nicholas J Leeper

Int J Mol Sci· June 2025

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Effect of Targeting ApoC-III With Plozasiran on Lipoprotein Particle Size and Number in Hypertriglyceridemia.
Christie M Ballantyne, Daniel Gaudet, Robert S Rosenson, Robert A Hegele, Rong Zhou, Nicholas J Leeper

J Am Coll Cardiol· May 2025

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The antipsychotic drug thiothixene stimulates macrophages to clear pathogenic cells by inducing arginase 1 and continual efferocytosis.
Yoko Kojima, Zhongde Ye, Fudi Wang, Mozhgan Lotfi, Caitlin Fox Bell, Nicholas J Leeper

Sci Signal· April 2025

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Plozasiran for Managing Persistent Chylomicronemia and Pancreatitis Risk. Reply.
Gerald F Watts, Robert A Hegele, Nicholas J Leeper

N Engl J Med· April 2025

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Temporal Effects of Plozasiran on Lipids and Lipoproteins in Persistent Chylomicronemia.
Gerald F Watts, Robert A Hegele, Robert S Rosenson, Ira J Goldberg, Antonio Gallo, Nicholas J Leeper

Circulation· March 2025

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Vascular smooth muscle cell plasticity in the tumor microenvironment.
Caitlin F Bell, Richard A Baylis, Nicolas G Lopez, Wei Feng Ma, Hua Gao, Nicholas J Leeper

Cancer Commun (Lond)· February 2025

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Plozasiran for Managing Persistent Chylomicronemia and Pancreatitis Risk.
Gerald F Watts, Robert S Rosenson, Robert A Hegele, Ira J Goldberg, Antonio Gallo, Nicholas J Leeper

N Engl J Med· January 2025

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Cardiovascular Disease and Breast Cancer Stage at Diagnosis.
Ivan Angelov, Allen M Haas, Elizabeth Brock, Lingfeng Luo, Jing Zhao, Nicholas J Leeper

JAMA Netw Open· January 2025

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Characterization of peripheral artery disease and associations with traditional risk factors, mobility, and biomarkers in the project baseline health study.
Jacquelyn B Kercheval, Dennis I Narcisse, Maggie Nguyen, Sunil V Rao, J Antonio Gutierrez, Nicholas J Leeper

Am Heart J· September 2024

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Pro-efferocytic nanotherapies reduce vascular inflammation without inducing anemia in a large animal model of atherosclerosis.
Sharika Bamezai, Yapei Zhang, Manisha Kumari, Mozhgan Lotfi, Tom Alsaigh, Nicholas J Leeper

Nat Commun· September 2024

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BST2 induces vascular smooth muscle cell plasticity and phenotype switching during cancer progression.
Caitlin F Bell, Richard A Baylis, Nicolas G Lopez, Wei Feng Ma, Hua Gao, Nicholas J Leeper

bioRxiv· September 2024

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Postdoctoral T32 training is correlated with obtaining an academic primarily research faculty position.
Adrienne L Mueller, Addie Schnirel, Sofie Kleppner, Philip Tsao, Nicholas J Leeper

PLoS One· June 2024

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A Glimpse Into the Black Box: Using Machine Learning to Prioritize Predictors of Vascular Disease.
Nicholas J Leeper, Shaunak S Adkar

JACC Adv· September 2023

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