Publications by authors named "Nicholas M Smith"

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Landing mosquitoes bounce when engaging a substrate.
Nicholas M Smith, Jasmine B Balsalobre, Mona Doshi, Bradley J Willenberg, Andrew K Dickerson

September 2020

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Whole-body distribution of three phages characterized by a translational physiologically based pharmacokinetic model.
Arne Echterhof, Tejas Dharmaraj, Patrick Blankenberg, Bobby Targ, Thomas D Nguyen, Nicholas M Smith

Antimicrob Agents Chemother· December 2025

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Resensitizing the Untreatable: Zidovudine and Polymyxin Combinations to Combat Pan-Drug-Resistant .
Jan Naseer Kaur, Jack F Klem, Gebremedhin S Hailu, Nader N Nasief, Yang Liu, Nicholas M Smith

Pharmaceuticals (Basel)· October 2025

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Combatting mobile colistin-resistant (MCR), metallo-β-lactamase (MBL)-producing persisters.
Jack F Klem, Jan Naseer Kaur, Yang Liu, Katie Rose Boissonneault, Shivali Kapoor, Nicholas M Smith

JAC Antimicrob Resist· August 2025

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Pharmacodynamics of aztreonam/ceftazidime/avibactam and polymyxin B versus New Delhi MBL-producing Acinetobacter baumannii.
Jacob T Dumbleton, Anant P Shah, Brian M Ho, Navaldeep Singh, Harriet de Souza, Nicholas M Smith

JAC Antimicrob Resist· June 2025

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Pharmacodynamic Evaluation of Adjuvant Targets: Low Molecular Weight PBP7/8 Effects on β-Lactam Activity Against Carbapenem-Resistant Acinetobacter Baumannii.
Brian M Ho, Jingxiu Jin, Jacob T Sanborn, Thomas D Nguyen, Navaldeep Singh, Nicholas M Smith

Pharmaceuticals (Basel)· June 2025

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Whole-body Bacteriophage Distribution Characterized by a Physiologically based Pharmacokinetic Model.
Arne Echterhof, Tejas Dharmaraj, Patrick Blankenberg, Bobby Targ, Paul L Bollyky, Nicholas M Smith

bioRxiv· February 2025

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Maximally precise combinations to overcome metallo-β-lactamase-producing .
Jan Naseer Kaur, Jack F Klem, Yang Liu, Katie Rose Boissonneault, Patricia N Holden, Nicholas M Smith

Antimicrob Agents Chemother· October 2024

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PBP-3 directed therapy in VIM-producing Pseudomonas aeruginosa creates bacterial transformers, persisters in disguise.
Nicholas M Smith, Katie Rose Boissonneault, Patricia N Holden, Jan Naseer Kaur, Jack F Klem

Int J Antimicrob Agents· September 2024

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Influence of β-lactam pharmacodynamics on the systems microbiology of gram-positive and gram-negative polymicrobial communities.
Nicholas M Smith, Harpreet Kaur, Ravneet Kaur, Trisha Minoza, Michael Kent

Front Pharmacol· June 2024

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Machine Learning-Led Optimization of Combination Therapy: Confronting the Public Health Threat of Extensively Drug Resistant Gram-Negative Bacteria.
Nicholas M Smith, Thomas D Nguyen, Thomas P Lodise, Liang Chen, Jan Naseer Kaur

Clin Pharmacol Ther· April 2024

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Comprehensive stability analysis of 13 β-lactams and β-lactamase inhibitors in media, and novel supplement dosing strategy to mitigate thermal drug degradation.
Jieqiang Zhou, Yuli Qian, Yinzhi Lang, Yongzhen Zhang, Xun Tao, Nicholas M Smith

Antimicrob Agents Chemother· March 2024

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Urinary biomarkers as indicators of acute kidney injury in critically ill children exposed to vancomycin.
Autumn M Spyhalsky, Se Jin Kim, Calvin J Meaney, Nicholas M Smith, Dhaval K Shah

Pharmacotherapy· February 2024

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Next generation antibiotic combinations to combat pan-drug resistant Klebsiella pneumoniae.
Jan Naseer Kaur, Navaldeep Singh, Nicholas M Smith, Jack F Klem, Raymond Cha

Sci Rep· February 2024

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A mechanism-based pathway toward administering highly active N-phage cocktails.
Nicholas M Smith, Thomas D Nguyen, Wai Hoe Chin, Jacob T Sanborn, Harriet de Souza

Front Microbiol· November 2023

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Bayesian optimization of tacrolimus exposure in stable kidney transplant patients.
Thomas D Nguyen, Nicholas M Smith, Kris Attwood, Aijaz Gundroo, Shirley Chang

Pharmacotherapy· October 2023

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Mechanistic Insights to Combating NDM- and CTX-M-Coproducing Klebsiella pneumoniae by Targeting Cell Wall Synthesis and Outer Membrane Integrity.
Nicholas M Smith, Katie Rose Boissonneault, Liang Chen, Vidmantas Petraitis, Ruta Petraitiene

Antimicrob Agents Chemother· September 2022

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Bacterial Mixology: Combining Pharmacodynamic Models to Predict In Vitro Competition of MCR-1-Harboring .
Nicholas M Smith, Arthur Chan, Thomas D Nguyen, Jacob T Dumbleton

Antibiotics (Basel)· December 2021

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Open-source maximum a posteriori-bayesian dosing AdDS to current therapeutic drug monitoring: Adapting to the era of individualized therapy.
Nicholas M Smith, Arthur Chan, Laura A Wilkinson, Hubert C Chua, Thomas D Nguyen

Pharmacotherapy· November 2021

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Combatting the Rising Tide of Antimicrobial Resistance: Pharmacokinetic/Pharmacodynamic Dosing Strategies for Maximal Precision.
Hubert C Chua, Andy Tse, Nicholas M Smith, Kari A Mergenhagen, Raymond Cha

Int J Antimicrob Agents· March 2021

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Interaction of Staphylococcus aureus and Acinetobacter baumannii during β-Lactam Exposure.
Nicholas M Smith, Alexa Ang, Fanny Tan, Katelyn Macias, Sarah James

Antimicrob Agents Chemother· March 2021

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Bacterial brothers in arms: cooperation of Staphylococcus aureus and Pseudomonas aeruginosa during antimicrobial exposure.
Justin R Lenhard, Nicholas M Smith, Christine D Quach, Tuan Q Nguyen, Linh H Doan

J Antimicrob Chemother· September 2019

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Rational Combinations of Polymyxins with Other Antibiotics.
Phillip J Bergen, Nicholas M Smith, Tyler B Bedard, Zackery P Bulman, Raymond Cha

Adv Exp Med Biol· September 2019

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Organismal aggregations exhibit fluidic behaviors: a review.
Nicholas M Smith, Andrew K Dickerson, David Murphy

Bioinspir Biomim· February 2019

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Mosquitoes modulate leg dynamics at takeoff to accommodate surface roughness.
Nicholas M Smith, Grace V Clayton, Hiba A Khan, Andrew K Dickerson

Bioinspir Biomim· November 2018

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