Publications by authors named "Patric Jansson"

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Cancer stem cells: Masters of all traits.
Lionel Y W Leck, Yomna S Abd El-Aziz, Kelly J McKelvey, Kyung Chan Park, Sumit Sahni, Patric J Jansson

Biochim Biophys Acta Mol Basis Dis· March 2025

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Novel combinatorial autophagy inhibition therapy for triple negative breast cancers.
Yomna S Abd El-Aziz, Taymin du Toit-Thompson, Matthew J McKay, Mark P Molloy, Shihani Stoner, Patric J Jansson

Eur J Pharmacol· June 2024

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Inhibition of autophagy initiation: A novel strategy for oral squamous cell carcinomas.
Yomna S Abd El-Aziz, Matthew J McKay, Mark P Molloy, Betty McDowell, Elizabeth Moon, Patric J Jansson

Biochim Biophys Acta Mol Cell Res· February 2024

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Mitoribosomal synthetic lethality overcomes multidrug resistance in MYC-driven neuroblastoma.
Karolina Borankova, Maria Krchniakova, Lionel Y W Leck, Adela Kubistova, Jakub Neradil, Patric J Jansson

Cell Death Dis· November 2023

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Innovative thiosemicarbazones that induce multi-modal mechanisms to down-regulate estrogen-, progesterone-, androgen- and prolactin-receptors in breast cancer.
Faten Shehadeh-Tout, Heloisa H Milioli, Suraya Roslan, Patric J Jansson, Mahendiran Dharmasivam

Pharmacol Res· July 2023

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Physicochemistry shapes bioactivity landscape of pan-ABC transporter modulators: Anchor point for innovative Alzheimer's disease therapeutics.
Vigneshwaran Namasivayam, Katja Stefan, Lukas Gorecki, Jan Korabecny, Ondrej Soukup, Patric Jan Jansson

Int J Biol Macromol· September 2022

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The thiosemicarbazone, DpC, broadly synergizes with multiple anti-cancer therapeutics and demonstrates temperature- and energy-dependent uptake by tumor cells.
Mahendiran Dharmasivam, Mahan Gholam Azad, Rizwana Afroz, Vera Richardson, Patric J Jansson

Biochim Biophys Acta Gen Subj· August 2022

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A curated binary pattern multitarget dataset of focused ATP-binding cassette transporter inhibitors.
Sven Marcel Stefan, Patric Jan Jansson, Jens Pahnke, Vigneshwaran Namasivayam

Sci Data· July 2022

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Autophagy: A Key Player in Pancreatic Cancer Progression and a Potential Drug Target.
Josef Gillson, Yomna S Abd El-Aziz, Lionel Y W Leck, Patric J Jansson, Nick Pavlakis

Cancers (Basel)· July 2022

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Targeting Wnt/tenascin C-mediated cross talk between pancreatic cancer cells and stellate cells via activation of the metastasis suppressor NDRG1.
Bekesho Geleta, Faten S Tout, Syer Choon Lim, Sumit Sahni, Patric J Jansson

J Biol Chem· March 2022

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Autophagy: A promising target for triple negative breast cancers.
Yomna S Abd El-Aziz, Josef Gillson, Patric J Jansson, Sumit Sahni

Pharmacol Res· January 2022

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Emerging Role of Autophagy in the Development and Progression of Oral Squamous Cell Carcinoma.
Yomna S Abd El-Aziz, Lionel Y W Leck, Patric J Jansson, Sumit Sahni

Cancers (Basel)· December 2021

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Tumour Microenvironment Stress Promotes the Development of Drug Resistance.
Nicole A Seebacher, Maria Krchniakova, Alexandra E Stacy, Jan Skoda, Patric J Jansson

Antioxidants (Basel)· November 2021

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Breaking the cycle: Targeting of NDRG1 to inhibit bi-directional oncogenic cross-talk between pancreatic cancer and stroma.
Bekesho Geleta, Kyung Chan Park, Patric J Jansson, Sumit Sahni, Sanaz Maleki

FASEB J· February 2021

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Role of ABCB1 in mediating chemoresistance of triple-negative breast cancers.
Yomna S Abd El-Aziz, Andrew J Spillane, Patric J Jansson, Sumit Sahni

Biosci Rep· February 2021

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Patric J Jansson

Autophagy· January 2021

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Ascorbate and Tumor Cell Iron Metabolism: The Evolving Story and Its Link to Pathology.
Dong-Hun Bae, Mahan Gholam Azad, Danuta S Kalinowski, Darius J R Lane, Patric J Jansson

Antioxid Redox Signal· October 2020

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Acireductone dioxygenase 1 (ADI1) is regulated by cellular iron by a mechanism involving the iron chaperone, PCBP1, with PCBP2 acting as a potential co-chaperone.
Dong-Hun Bae, Darius J R Lane, Aritee R Siafakas, Robert Sutak, Jasmina Paluncic, Patric J Jansson

Biochim Biophys Acta Mol Basis Dis· October 2020

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Unique targeting of androgen-dependent and -independent AR signaling in prostate cancer to overcome androgen resistance.
Syer C Lim, Patric J Jansson, Stephen J Assinder, Sanaz Maleki, Des R Richardson

FASEB J· September 2020

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NDRG1 suppresses basal and hypoxia-induced autophagy at both the initiation and degradation stages and sensitizes pancreatic cancer cells to lysosomal membrane permeabilization.
Sumit Sahni, Josef Gillson, Kyung Chan Park, Shannon Chiang, Lionel Yi Wen Leck, Patric J Jansson

Biochim Biophys Acta Gen Subj· August 2020

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Overcoming tamoxifen resistance in oestrogen receptor-positive breast cancer using the novel thiosemicarbazone anti-cancer agent, DpC.
Sundus N Maqbool, Syer C Lim, Kyung Chan Park, Rumeza Hanif, Des R Richardson, Patric J Jansson

Br J Pharmacol· May 2020

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The growing evidence for targeting P-glycoprotein in lysosomes to overcome resistance.
Sven Marcel Stefan, Patric J Jansson, Danuta S Kalinowski, Rukhsana Anjum, Mahendiran Dharmasivam

Future Med Chem· March 2020

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Thiosemicarbazones suppress expression of the c-Met oncogene by mechanisms involving lysosomal degradation and intracellular shedding.
Kyung Chan Park, Bekesho Geleta, Lionel Yi Wen Leck, Jasmina Paluncic, Shannon Chiang, Patric J Jansson

J Biol Chem· January 2020

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The biochemical and molecular mechanisms involved in the role of tumor micro-environment stress in development of drug resistance.
Lina Al-Akra, Dong-Hun Bae, Lionel Y W Leck, Des R Richardson, Patric J Jansson

Biochim Biophys Acta Gen Subj· September 2019

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Tumor-induced neoangiogenesis and receptor tyrosine kinases - Mechanisms and strategies for acquired resistance.
Madiha Yunus, Patric J Jansson, Zaklina Kovacevic, Danuta S Kalinowski, Des R Richardson

Biochim Biophys Acta Gen Subj· July 2019

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