Publications by authors named "Patrick Arbuthnot"

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Self-amplifying RNA vaccines for infectious diseases.
Kristie Bloom, Fiona van den Berg, Patrick Arbuthnot

Gene Ther· April 2021

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Advancing the course of HIV genomics research in Africa.
Francis E Agamah, Patrick Arbuthnot, Paulina Tindana, Nchangwi Synthia Munung, Mary Kasule

BMJ Glob Health· August 2025

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Generating mRNA Encoding Anti-HBV Designer Epigenome Modifiers.
Prashika Singh, Tafadzwa Mlambo, Kristie Bloom, Claudio Mussolino, Patrick Arbuthnot

Methods Mol Biol· August 2025

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Lipid Nanoparticle-Encapsulated TALEN-Encoding mRNA Inactivates Hepatitis B Virus Replication in Cultured Cells and Transgenic Mice.
Tiffany Smith, Prashika Singh, Ridhwaanah Bhana, Dylan Kairuz, Kristie Bloom, Patrick Arbuthnot

Viruses· August 2025

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Generation and Treatment of a Novel Severe Model of Visceral Gaucher Disease by Genetic Therapy.
Amy F Geard, Giulia Massaro, Michael P Hughes, Patrick Arbuthnot, Simon N Waddington

Pharmaceutics· May 2025

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In Vitro Transcribed Artificial Primary MicroRNA for the Inhibition of Hepatitis B Virus Gene Expression in Cultured Cells.
Creanne Shrilall, Patrick Arbuthnot, Abdullah Ely

Microorganisms· March 2025

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Long-term inhibition of Hepatitis B virus gene expression by a primary microrna expressing ancestral adeno-associated viral vector.
Njabulo Ziphezinhle Mnyandu, Shonisani Wendy Limani, Abdullah Ely, Reubina Wadee, Patrick Arbuthnot

Virol J· February 2025

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Prospects of viral vector-mediated delivery of sequences encoding anti-HBV designer endonucleases.
Ridhwaanah Jacobs, Prashika Singh, Tiffany Smith, Patrick Arbuthnot, Mohube Betty Maepa

Gene Ther· January 2025

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Bridging gene therapy and next-generation vaccine technologies.
Kristie Bloom, Abdullah Ely, Mohube Betty Maepa, Patrick Arbuthnot

Gene Ther· January 2025

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Recent Advances in Designing Adeno-Associated Virus-Based Vaccines Against Viral Infections.
Njabulo Mnyandu, Ridhwaanah Jacobs, Patrick Arbuthnot, Mohube Betty Maepa

Pharmaceutics· October 2024

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Making genome editing a success story in Africa.
Hussein M Abkallo, Patrick Arbuthnot, Thomas O Auer, Dave K Berger, Johan Burger

Nat Biotechnol· April 2024

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AAV Immunotoxicity: Implications in Anti-HBV Gene Therapy.
Ridhwaanah Jacobs, Makafui Dennis Dogbey, Njabulo Mnyandu, Keila Neves, Stefan Barth, Patrick Arbuthnot

Microorganisms· December 2023

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Opportunities and challenges of leveraging COVID-19 vaccine innovation and technologies for developing sustainable vaccine manufacturing capabilities in Africa.
Bavesh D Kana, Patrick Arbuthnot, Benjamin K Botwe, Yahya E Choonara, Fatima Hassan

Lancet Infect Dis· August 2023

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Production, Characterization, and Assessment of Permanently Cationic and Ionizable Lipid Nanoparticles for Use in the Delivery of Self-Amplifying RNA Vaccines.
Dylan Kairuz, Nazia Samudh, Abdullah Ely, Patrick Arbuthnot, Kristie Bloom

Pharmaceutics· April 2023

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Advancing mRNA technologies for therapies and vaccines: An African context.
Dylan Kairuz, Nazia Samudh, Abdullah Ely, Patrick Arbuthnot, Kristie Bloom

Front Immunol· November 2022

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Adenoviral Vectors: Potential as Anti-HBV Vaccines and Therapeutics.
Tasneem Farhad, Keila Neves, Patrick Arbuthnot, Mohube Betty Maepa

Genes (Basel)· October 2022

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Hepatitis B Virus Research in South Africa.
Mohube B Maepa, Abdullah Ely, Anna Kramvis, Kristie Bloom, Kubendran Naidoo, Patrick Arbuthnot

Viruses· August 2022

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Diversity of Dysregulated Long Non-Coding RNAs in HBV-Related Hepatocellular Carcinoma.
Nazia Samudh, Creanne Shrilall, Patrick Arbuthnot, Kristie Bloom, Abdullah Ely

Front Immunol· March 2022

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Advances in designing Adeno-associated viral vectors for development of anti-HBV gene therapeutics.
Njabulo Mnyandu, Shonisani Wendy Limani, Patrick Arbuthnot, Mohube Betty Maepa

Virol J· December 2021

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In Vivo Modelling of Hepatitis B Virus Subgenotype A1 Replication Using Adeno-Associated Viral Vectors.
Shonisani Wendy Limani, Njabulo Mnyandu, Abdullah Ely, Reubina Wadee, Anna Kramvis, Patrick Arbuthnot

Viruses· November 2021

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Targeted multi-epitope switching enables straightforward positive/negative selection of CAR T cells.
Laura Mosti, Lukas M Langner, Kay O Chmielewski, Patrick Arbuthnot, Jamal Alzubi

Gene Ther· September 2021

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Improved Specificity and Safety of Anti-Hepatitis B Virus TALENs Using Obligate Heterodimeric I Nuclease Domains.
Tiffany Smith, Prashika Singh, Kay Ole Chmielewski, Kristie Bloom, Toni Cathomen, Patrick Arbuthnot

Viruses· July 2021

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Hepatitis B virus: promising drug targets and therapeutic implications.
Mohube Betty Maepa, Kristie Bloom, Abdullah Ely, Patrick Arbuthnot

Expert Opin Ther Targets· June 2021

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Silencing hepatitis B virus covalently closed circular DNA: The potential of an epigenetic therapy approach.
Prashika Singh, Dylan Kairuz, Patrick Arbuthnot, Kristie Bloom

World J Gastroenterol· June 2021

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Recent Update on the Role of Circular RNAs in Hepatocellular Carcinoma.
Abdullah Ely, Kristie Bloom, Mohube Betty Maepa, Patrick Arbuthnot

J Hepatocell Carcinoma· January 2021

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