Publications by authors named "R G Alken"

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Deuterium-substituted L-DOPA displays increased behavioral potency and dopamine output in an animal model of Parkinson's disease: comparison with the effects produced by L-DOPA and an MAO-B inhibitor.
Torun Malmlöf, Kristin Feltmann, Åsa Konradsson-Geuken, Frank Schneider, Rudolf-Giesbert Alken

J Neural Transm (Vienna)· February 2015

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Cardiovascular effects, pharmacokinetics and cross-reactivity in digitalis glycoside immunoassays of an antidiarrheal uzara root extract.
Sven Schmiedl, Anne Ritter, Jacek Szymanski, Frank Schneider, Thomas Plecko, R Giesbert Alken

Int J Clin Pharmacol Ther· October 2012

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Deuterium substitutions in the L-DOPA molecule improve its anti-akinetic potency without increasing dyskinesias.
Torun Malmlöf, Daniella Rylander, Rudolf-Giesbert Alken, Frank Schneider, Torgny H Svensson

Exp Neurol· October 2010

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Synergistic effects of deuterium oxide and gemcitabine in human pancreatic cancer cell lines.
Yvonne Bader, Johannes Hartmann, Zsuzsanna Horvath, Philipp Saiko, Michael Grusch, Rudolf-Giesbert Alken

Cancer Lett· February 2008

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Changed phosphodiesterase selectivity and enhanced in vitro efficacy by selective deuteration of sildenafil.
Frank Schneider, Emine Mattern-Dogru, Moritz Hillgenberg, Rudolf-Giesbert Alken

Arzneimittelforschung· September 2007

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