Publications by authors named "R LeDuc"

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Structural insights into frog skin-derived cyclic peptides as selective matriptase inhibitors.
Agata Gitlin-Domagalska, Malihe Hassanzadeh, Aleksandra Helbik-Maciejewska, Matthieu Lepage, Alexandre Joushomme, Richard Leduc

Eur J Med Chem· January 2026

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Structure-Guided Optimization of Selective Covalent Reversible Peptidomimetic Inhibitors Targeting TMPRSS6.
Walid Guerrab, Matthieu Lepage, Antoine Désilets, Alexandre Joushomme, Michael Desgagné, Richard Leduc

J Med Chem· December 2025

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Aggregation-prone alpha-synuclein proteoforms and dysregulated molecular signatures in the vermiform appendix of synucleinopathy patients.
Ehraz Anis, Saima Zameer, Joshua Wierenga, Peipei Li, Jacek W Sikora, Richard D LeDuc

bioRxiv· October 2025

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Optimizing the pharmacokinetics and selectivity of TMPRSS2 inhibitors.
Sára Ferková, Matthieu Lepage, Antoine Désilets, Kevin Assouvie, Gabriel Lemieux, Richard Leduc

Eur J Med Chem· September 2025

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Decoding ADGRE5: How Proteolytic Cleavage and Mechanical Forces Unleash Cellular Signals.
Ana L Moreno-Salinas, Arturo Mancini, Samya Aouad, Herthana Kandasamy, Sandra Morissette, Richard Leduc

Cells· August 2025

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