Publications by authors named "R Ruel"

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DDB1 engagement defines the selectivity of S656 analogs for cyclin K degradation over CDK inhibition.
Céline Moison, Rodrigo Mendoza-Sanchez, Deanne Gracias, Doris A Schuetz, Jean-François Spinella, Réjean Ruel

EMBO Rep· June 2025

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Structure-based design of small molecule inhibitors of the cagT4SS ATPase Cagα of .
Claire Morin, Vijay Tailor Verma, Tarun Arya, Bastien Casu, Eric Jolicoeur, Réjean Ruel

Biochem Cell Biol· June 2024

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mutations provide genetic vulnerability to copper ionophores in human acute myeloid leukemia.
Céline Moison, Deanne Gracias, Julie Schmitt, Simon Girard, Jean-François Spinella, Réjean Ruel

Sci Adv· March 2024

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Discovery of Benzodiazepine-Based Inhibitors of the E2 Enzyme UBCH10 from a Cell-Based p21 Degradation Screen.
Benoit Pelletier, Stéphanie Duhamel, Guillaume Tambutet, Scott Jarvis, Patrick Cléroux, Réjean Ruel

ACS Chem Biol· May 2023

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Vesicular trafficking is a key determinant of the statin response in acute myeloid leukemia.
Jana Krosl, Marie-Eve Bordeleau, Céline Moison, Tara MacRae, Isabel Boivin, Réjean Ruel

Blood Adv· January 2022

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