Publications by authors named "Rachel A Silverstein"

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Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease.
Kiran Musunuru, Sarah A Grandinette, Xiao Wang, Taylor R Hudson, Kevin Briseno, Anne Marie Berry, Julia L Hacker, Alvin Hsu, Rachel A Silverstein, Logan T Hille

June 2025

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Treatment of a severe vascular disease using a bespoke CRISPR-Cas9 base editor in mice.
Christiano R R Alves, Sabyasachi Das, Vijai Krishnan, Leillani L Ha, Lauren R Fox, Rachel A Silverstein

Nat Biomed Eng· September 2025

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Custom CRISPR-Cas9 PAM variants via scalable engineering and machine learning.
Rachel A Silverstein, Nahye Kim, Ann-Sophie Kroell, Russell T Walton, Justin Delano

Nature· July 2025

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Treatment of a Severe Vascular Disease via a Bespoke CRISPR-Cas9 Base Editor.
Christiano R R Alves, Sabyasachi Das, Vijai Krishnan, Leillani L Ha, Lauren R Fox, Rachel A Silverstein

bioRxiv· November 2024

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PAM-flexible genome editing with an engineered chimeric Cas9.
Lin Zhao, Sabrina R T Koseki, Rachel A Silverstein, Nadia Amrani, Christina Peng

Nat Commun· October 2023

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Precise DNA cleavage using CRISPR-SpRYgests.
Kathleen A Christie, Jimmy A Guo, Rachel A Silverstein, Roman M Doll, Megumu Mabuchi

Nat Biotechnol· March 2023

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Evolution of CRISPR-associated endonucleases as inferred from resurrected proteins.
Borja Alonso-Lerma, Ylenia Jabalera, Sara Samperio, Matias Morin, Almudena Fernandez, Rachel A Silverstein

Nat Microbiol· January 2023

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