Publications by authors named "Ran Brosh"

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On the genetic basis of tail-loss evolution in humans and apes.
Bo Xia, Weimin Zhang, Guisheng Zhao, Xinru Zhang, Jiangshan Bai, Ran Brosh, Aleksandra Wudzinska, Emily Huang, Hannah Ashe, Gwen Ellis

Nature· February 2024

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Myelin pathology is a key feature of X-linked Dystonia Parkinsonism.
Priya Prakash, Kerry C Limberg, Weimin Zhang, Yu Zhao, Klaudia F Laborc, Ran Brosh

bioRxiv· October 2025

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Genome writing to dissect consequences of SVA retrotransposon disease X-Linked Dystonia Parkinsonism.
Weimin Zhang, Yu Zhao, Priya Prakash, Heather L Appleby, Kelly Barriball, Ran Brosh

bioRxiv· October 2025

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Assemblatron: An Automated Workflow for High-Throughput Assembly of Big-DNA Libraries.
Antonio Vela Gartner, Luisa F Quispe, Klaus-Peter Rühmann, J Andrew Martin, Jordan M Welker, Ran Brosh

bioRxiv· July 2025

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Genomic context sensitizes regulatory elements to genetic disruption.
Raquel Ordoñez, Weimin Zhang, Gwen Ellis, Yinan Zhu, Hannah J Ashe, Ran Brosh

Mol Cell· May 2024

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Synthetic reversed sequences reveal default genomic states.
Brendan R Camellato, Ran Brosh, Hannah J Ashe, Matthew T Maurano, Jef D Boeke

Nature· April 2024

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Genomic context sensitizes regulatory elements to genetic disruption.
Raquel Ordoñez, Weimin Zhang, Gwen Ellis, Yinan Zhu, Hannah J Ashe, Ran Brosh

bioRxiv· March 2024

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Author Correction: Longitudinal scRNA-seq analysis in mouse and human informs optimization of rapid mouse astrocyte differentiation protocols.
Paul W Frazel, David Labib, Theodore Fisher, Ran Brosh, Nicolette Pirjanian

Nat Neurosci· January 2024

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Mouse genome rewriting and tailoring of three important disease loci.
Weimin Zhang, Ilona Golynker, Ran Brosh, Alvaro Fajardo, Yinan Zhu

Nature· November 2023

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Longitudinal scRNA-seq analysis in mouse and human informs optimization of rapid mouse astrocyte differentiation protocols.
Paul W Frazel, David Labib, Theodore Fisher, Ran Brosh, Nicolette Pirjanian

Nat Neurosci· October 2023

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CREEPY: CRISPR-mediated editing of synthetic episomes in yeast.
Yu Zhao, Camila Coelho, Stephanie Lauer, Miłosz Majewski, Jon M Laurent, Ran Brosh

Nucleic Acids Res· July 2023

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Regulatory architecture of housekeeping genes is driven by promoter assemblies.
Marion Dejosez, Alessandra Dall'Agnese, Mahesh Ramamoorthy, Jesse Platt, Xing Yin, Ran Brosh

Cell Rep· May 2023

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Synthetic regulatory genomics uncovers enhancer context dependence at the Sox2 locus.
Ran Brosh, Camila Coelho, André M Ribeiro-Dos-Santos, Gwen Ellis, Megan S Hogan

Mol Cell· April 2023

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Synthetic regulatory reconstitution reveals principles of mammalian cluster regulation.
Sudarshan Pinglay, Milica Bulajić, Dylan P Rahe, Emily Huang, Ran Brosh

Science· July 2022

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A conditional counterselectable knockout in mouse embryonic stem cells for advanced genome writing applications.
Weimin Zhang, Ran Brosh, Laura H McCulloch, Yinan Zhu, Hannah Ashe

iScience· June 2022

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Genomic context sensitivity of insulator function.
André M Ribeiro-Dos-Santos, Megan S Hogan, Raven D Luther, Ran Brosh, Matthew T Maurano

Genome Res· March 2022

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De novo assembly and delivery to mouse cells of a 101 kb functional human gene.
Leslie A Mitchell, Laura H McCulloch, Sudarshan Pinglay, Henri Berger, Nazario Bosco, Ran Brosh

Genetics· May 2021

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A versatile platform for locus-scale genome rewriting and verification.
Ran Brosh, Jon M Laurent, Raquel Ordoñez, Emily Huang, Megan S Hogan

Proc Natl Acad Sci U S A· March 2021

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Memory of Divisional History Directs the Continuous Process of Primitive Hematopoietic Lineage Commitment.
Jeffrey M Bernitz, Katrina Rapp, Michael G Daniel, Dmitrii Shcherbinin, Ye Yuan, Ran Brosh

Stem Cell Reports· April 2020

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A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons.
Anastasiya Sybirna, Walfred W C Tang, Merrick Pierson Smela, Sabine Dietmann, Wolfram H Gruhn, Ran Brosh

Nat Commun· March 2020

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A dual molecular analogue tuner for dissecting protein function in mammalian cells.
Ran Brosh, Iryna Hrynyk, Jessalyn Shen, Avinash Waghray, Ning Zheng

Nat Commun· May 2016

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Tbx3 Controls Dppa3 Levels and Exit from Pluripotency toward Mesoderm.
Avinash Waghray, Néstor Saiz, Anitha D Jayaprakash, Ana G Freire, Dmitri Papatsenko, Ran Brosh

Stem Cell Reports· July 2015

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Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues.
Gilad Landan, Netta Mendelson Cohen, Zohar Mukamel, Amir Bar, Alina Molchadsky, Ran Brosh

Nat Genet· November 2012

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Various p53 mutant proteins differently regulate the Ras circuit to induce a cancer-related gene signature.
Hilla Solomon, Yosef Buganim, Ira Kogan-Sakin, Leslie Pomeraniec, Yael Assia, Ran Brosh

J Cell Sci· July 2012

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Transcriptional activity of ATF3 in the stromal compartment of tumors promotes cancer progression.
Yosef Buganim, Shalom Madar, Yoach Rais, Leslie Pomeraniec, Einav Harel, Ran Brosh

Carcinogenesis· December 2011

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