Publications by authors named "Randy Brutkiewicz"

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Detecting Beta-amyloid Plaque via Low Rank Based Orthogonal Projection and Spatial-spectrum Detector Using High-resolution Quantitative Susceptibility Mapping for Preclinical Studies.
Jie Chen, Xinyue Han, Zhuoheng Liu, Chengqian Zhou, Rui Hu, Randy R Brutkiewicz

IEEE Trans Biomed Eng· September 2025

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What would it take to prove that a chronic infection is a causal agent in Alzheimer's disease?
Randy R Brutkiewicz, Wei Cao, David Morgan, Roberta Souza Dos Reis, Vidyani Suryadevara

Trends Neurosci· August 2025

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The MR1/MAIT cell axis impacts the gut-brain axis through both cognition and microbial community structure in 5XFAD mice.
Season K Wyatt-Johnson, Jay M Desai, Autumn Wireman, Peter Eipers, Casey Morrow, Randy R Brutkiewicz

Alzheimers Dement· July 2025

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Blocking the innate immune CD1d/NKT cell axis prevents the development of cortical hyperexcitability and posttraumatic epilepsy.
Xingjie Ping, Wenhui Xiong, Raj Priya, Jianyun Liu, Season K Wyatt-Johnson, Randy R Brutkiewicz

Epilepsia· June 2025

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The MR1/MAIT cell axis enhances dystrophic neurite development in Alzheimer's disease.
Season K Wyatt-Johnson, Samantha Ackley, Jalyn Warren, Raj Priya, Jun Wan, Randy R Brutkiewicz

Alzheimers Dement· February 2025

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Myeloid antigen-presenting cells in neurodegenerative diseases: a focus on classical and non-classical MHC molecules.
Reham Afify, Katherine Lipsius, Season J Wyatt-Johnson, Randy R Brutkiewicz

Front Neurosci· December 2024

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Enrichment of liver MAIT cells in a mouse model of Alzheimer's disease.
Season K Wyatt-Johnson, Holly N Kersey, Randy R Brutkiewicz

J Neuroimmunol· May 2024

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The immune system in neurological diseases: What innate-like T cells have to say.
Season K Wyatt-Johnson, Reham Afify, Randy R Brutkiewicz

J Allergy Clin Immunol· April 2024

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The MR1/MAIT cell axis in CNS diseases.
Rashmi Shrinivasan, Season K Wyatt-Johnson, Randy R Brutkiewicz

Brain Behav Immun· February 2024

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CD1d-dependent neuroinflammation impairs tissue repair and functional recovery following a spinal cord injury.
Xiangbing Wu, Jianyun Liu, Wei Li, Mohammad Faizan Khan, Heqiao Dai, Randy R Brutkiewicz

bioRxiv· October 2023

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Control of the temporal development of Alzheimer's disease pathology by the MR1/MAIT cell axis.
Season K Wyatt-Johnson, Holly N Kersey, Juan F Codocedo, Kathy L Newell, Gary E Landreth, Randy R Brutkiewicz

J Neuroinflammation· March 2023

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Multispecific targeting of glioblastoma with tumor microenvironment-responsive multifunctional engineered NK cells.
Jiao Wang, Sandra Toregrosa-Allen, Bennett D Elzey, Sagar Utturkar, Nadia Atallah Lanman, Randy R Brutkiewicz

Proc Natl Acad Sci U S A· November 2021

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Publisher Correction: Genetic engineering of porcine endothelial cell lines for evaluation of human-to-pig xenoreactive immune responses.
Ping Li, Julia R Walsh, Kevin Lopez, Abdulkadir Isidan, Wenjun Zhang, Randy R Brutkiewicz

Sci Rep· August 2021

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Genetic engineering of porcine endothelial cell lines for evaluation of human-to-pig xenoreactive immune responses.
Ping Li, Julia R Walsh, Kevin Lopez, Abdulkadir Isidan, Wenjun Zhang, Randy R Brutkiewicz

Sci Rep· June 2021

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MR1 Tetramer-Based Artificial APCs Expand MAIT Cells from Human Peripheral Blood That Effectively Kill Glioblastoma Cells.
Raj Priya, Randy R Brutkiewicz

Immunohorizons· June 2021

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Sex discrepancy in the reduction of mucosal-associated invariant T cells caused by obesity.
Jianyun Liu, Hongmei Nan, Randy R Brutkiewicz, Jose Casasnovas, Kok Lim Kua

Immun Inflamm Dis· March 2021

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MR1 overexpression correlates with poor clinical prognosis in glioma patients.
Phillip Kubica, Montserrat Lara-Velazquez, Marpe Bam, Seema Siraj, Irene Ong, Randy R Brutkiewicz

Neurooncol Adv· February 2021

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Brain astrocytes and microglia express functional MR1 molecules that present microbial antigens to mucosal-associated invariant T (MAIT) cells.
Raj Priya, Randy R Brutkiewicz

J Neuroimmunol· December 2020

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The Complexity of Microglial Interactions With Innate and Adaptive Immune Cells in Alzheimer's Disease.
Season K Wyatt-Johnson, Randy R Brutkiewicz

Front Aging Neurosci· November 2020

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JNK2 modulates the CD1d-dependent and -independent activation of iNKT cells.
Jianyun Liu, Richard M Gallo, Masood A Khan, Abhirami K Iyer, Ian M Kratzke, Randy R Brutkiewicz

Eur J Immunol· February 2019

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A Potent CD1d-binding Glycolipid for iNKT-Cell-based Therapy Against Human Breast Cancer.
Toshiyuki Seki, Jianyun Liu, Randy R Brutkiewicz, Moriya Tsuji

Anticancer Res· February 2019

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Immune evasion of the CD1d/NKT cell axis.
Randy R Brutkiewicz, Laura Yunes-Medina, Jianyun Liu

Curr Opin Immunol· June 2018

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Neurofibromin 1 Impairs Natural Killer T-Cell-Dependent Antitumor Immunity against a T-Cell Lymphoma.
Jianyun Liu, Richard M Gallo, Masood A Khan, Gourapura J Renukaradhya, Randy R Brutkiewicz

Front Immunol· January 2018

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The Toll-like receptor 9 signalling pathway regulates MR1-mediated bacterial antigen presentation in B cells.
Jianyun Liu, Randy R Brutkiewicz

Immunology· October 2017

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Cell Signaling Pathways That Regulate Antigen Presentation.
Randy R Brutkiewicz

J Immunol· October 2016

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