Publications by authors named "Rasika A Mathias"

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Adaptive evolution of the FADS gene cluster within Africa.
Rasika A Mathias, Wenqing Fu, Joshua M Akey, Hannah C Ainsworth, Dara G Torgerson, Ingo Ruczinski, Susan Sergeant, Kathleen C Barnes, Floyd H Chilton

PLoS One· March 2013

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Mediation of Polygenic Asthma Risk Through Gene Expression.
Rakesh Natarajan, Brooke Szczesny, Kanika Kanchan, Erika Esquinca, Meher Preethi Boorgula, Rasika A Mathias

Allergy· December 2025

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The effect of long-term adherence to physical activity recommendations in midlife on plasma proteins associated with frailty in the Atherosclerosis Risk in Communities (ARIC) study.
Fangyu Liu, Jennifer A Schrack, Keenan A Walker, Jeremy Walston, Rasika A Mathias

Eur J Epidemiol· October 2025

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Prediction and characterization of genetically regulated expression of asthma tissues from African-ancestry populations.
Sarah D Slack, Erika Esquinca, Christopher H Arehart, Meher Preethi Boorgula, Brooke Szczesny, Rasika A Mathias

J Allergy Clin Immunol· September 2025

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Association of genetic scores related to insulin resistance with neurological outcomes in ancestrally diverse cohorts from the Trans-Omics for Precision Medicine (TOPMed) program.
Chloé Sarnowski, Yixin Zhang, Farah Ammous, Lincoln M P Shade, Daniel DiCorpo, Rasika A Mathias

Commun Biol· September 2025

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Genetic study of von Willebrand factor antigen levels ≤ 50 IU/dL identifies variants associated with increased risk of von Willebrand disease and bleeding.
Rachel K Friedman, Adam S Heath, Jennifer E Huffman, James T Baker, Natalie R Hasbani, Rasika A Mathias

J Thromb Haemost· August 2025

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A rapid accurate approach to inferring pedigrees in endogamous populations.
Cole M Williams, Brooke A Scelza, Sarah D Slack, Neus Font-Porterias, Dana R Al-Hindi, Rasika A Mathias

Genetics· August 2025

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A data model for population descriptors in genomic research.
Alyna T Khan, Clement Adebamowo, Stephanie M Fullerton, Jibril Hirbo, Iain R Konigsberg, Rasika A Mathias

Am J Hum Genet· July 2025

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Cardiovascular-Derived Circulating Cell-Free DNA Fragments Are Associated With Frailty and Increased Cardiovascular Events in Older Adults.
Lolita S Nidadavolu, David W Sosnowski, Nikita Sivakumar, Alessandra Merino Gomez, Yuqiong Wu, Rasika A Mathias

J Gerontol A Biol Sci Med Sci· June 2025

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Whole genome sequence association analysis of brain structural volume measures in the NHLBI TOPMed Program highlights novel loci in diverse participants.
Lincoln Mp Shade, Mohsen Sharifitabar, Alexa Beiser, Claudia L Satizabal, Thomas H Mosley, Rasika A Mathias

medRxiv· June 2025

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EndoPRS: Incorporating endophenotype information to improve polygenic risk scores for clinical endpoints-A study in asthma.
Elena V Kharitonova, Quan Sun, Franklin Ockerman, Brian Chen, Laura Y Zhou, Rasika A Mathias

Am J Hum Genet· May 2025

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Novel applications of large language models in clinical research.
Michael S Abers, Rasika A Mathias

J Allergy Clin Immunol· March 2025

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Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood.
Yasminka A Jakubek, Xiaolong Ma, Adrienne M Stilp, Fulong Yu, Jason Bacon, Rasika A Mathias

Am J Hum Genet· February 2025

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A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies.
Xihao Li, Han Chen, Margaret Sunitha Selvaraj, Eric Van Buren, Hufeng Zhou, Rasika A Mathias

Nat Comput Sci· February 2025

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Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants.
Kruthika R Iyer, Shoa L Clarke, Rodrigo Guarischi-Sousa, Ketrin Gjoni, Adam S Heath, Rasika A Mathias

J Am Heart Assoc· February 2025

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Prediction and Characterization of Genetically Regulated Expression of Target Tissues in Asthma.
Sarah D Slack, Erika Esquinca, Christopher H Arehart, Meher Preethi Boorgula, Brooke Szczesny, Rasika A Mathias

medRxiv· February 2025

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Session Introduction: Overcoming health disparities in precision medicine: Intersectional approaches in precision medicine.
Francisco M De La Vega, Kathleen C Barnes, Harris Bland, Todd Edwards, Keolu Fox, Rasika A Mathias

Pac Symp Biocomput· December 2024

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Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.
Jennifer E Huffman, Jayna Nicholas, Julie Hahn, Adam S Heath, Laura M Raffield, Rasika A Mathias

Blood· November 2024

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The effect of long-term adherence to physical activity recommendations in midlife on plasma proteins associated with frailty in the Atherosclerosis Risk in Communities (ARIC) study.
Fangyu Liu, Jennifer A Schrack, Keenan A Walker, Jeremy Walston, Rasika A Mathias

medRxiv· November 2024

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Mid-life plasma proteins associated with late-life prefrailty and frailty: a proteomic analysis.
Fangyu Liu, Jennifer A Schrack, Jeremy Walston, Rasika A Mathias, B Gwen Windham

Geroscience· October 2024

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Whole genome sequencing based analysis of inflammation biomarkers in the Trans-Omics for Precision Medicine (TOPMed) consortium.
Min-Zhi Jiang, Sheila M Gaynor, Xihao Li, Eric Van Buren, Adrienne Stilp, Rasika A Mathias

Hum Mol Genet· August 2024

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Epigenetic and proteomic signatures associate with clonal hematopoiesis expansion rate.
Taralynn M Mack, Michael A Raddatz, Yash Pershad, Daniel C Nachun, Kent D Taylor, Rasika A Mathias

Nat Aging· August 2024

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Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes.
Rebecca Keener, Surya B Chhetri, Carla J Connelly, Margaret A Taub, Matthew P Conomos, Rasika A Mathias

Nat Commun· May 2024

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Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations.
Brooke Szczesny, Meher Preethi Boorgula, Sameer Chavan, Monica Campbell, Randi K Johnson, Rasika A Mathias

Nat Commun· May 2024

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EndoPRS: Incorporating Endophenotype Information to Improve Polygenic Risk Scores for Clinical Endpoints.
Elena V Kharitonova, Quan Sun, Frank Ockerman, Brian Chen, Laura Y Zhou, Rasika A Mathias

medRxiv· May 2024

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Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification.
Paul S de Vries, Matthew P Conomos, Kuldeep Singh, Christopher J Nicholson, Deepti Jain, Rasika A Mathias

Nat Cardiovasc Res· December 2023

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