Publications by authors named "Rhonda D Cardin"

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An oral SARS-CoV-2 M inhibitor clinical candidate for the treatment of COVID-19.
Dafydd R Owen, Charlotte M N Allerton, Annaliesa S Anderson, Lisa Aschenbrenner, Melissa Avery, Simon Berritt, Britton Boras, Rhonda D Cardin, Anthony Carlo, Karen J Coffman

December 2021

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Integrated virologic analysis of resistance to nirmatrelvir/ritonavir in individuals across four phase 2/3 clinical studies for the treatment of COVID-19.
Mary Lynn Baniecki, Shunjie Guan, Devendra K Rai, Qingyi Yang, Jonathan T Lee, Rhonda D Cardin

EBioMedicine· August 2025

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Discovery of Nirmatrelvir (PF-07321332): A Potent, Orally Active Inhibitor of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) Main Protease.
Jamison B Tuttle, Christophe Allais, Charlotte M N Allerton, Annaliesa S Anderson, Joel T Arcari, Rhonda D Cardin

J Med Chem· April 2025

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Nirmatrelvir and molnupiravir maintain potent in vitro and in vivo antiviral activity against circulating SARS-CoV-2 omicron subvariants.
Romel Rosales, Briana L McGovern, M Luis Rodriguez, Rocio Leiva-Rebollo, Randy Diaz-Tapia, Rhonda D Cardin

Antiviral Res· October 2024

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A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19.
Charlotte M N Allerton, Joel T Arcari, Lisa M Aschenbrenner, Melissa Avery, Bruce M Bechle, Rhonda D Cardin

J Med Chem· August 2024

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In vitro selection and analysis of SARS-CoV-2 nirmatrelvir resistance mutations contributing to clinical virus resistance surveillance.
Yuao Zhu, Irina Yurgelonis, Stephen Noell, Qingyi Yang, Shunjie Guan, Rhonda D Cardin

Sci Adv· July 2024

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The Viral G-Protein-Coupled Receptor Homologs M33 and US28 Promote Cardiac Dysfunction during Murine Cytomegalovirus Infection.
Cassandra M Bonavita, Timothy M White, Joseph Francis, Helen E Farrell, Nicholas J Davis-Poynter, Rhonda D Cardin

Viruses· March 2023

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NPP-669, a Novel Broad-Spectrum Antiviral Therapeutic with Excellent Cellular Uptake, Antiviral Potency, Oral Bioavailability, Preclinical Efficacy, and a Promising Safety Margin.
Elke Lipka, Aaron M Chadderdon, Cheryl C Harteg, Matthew K Doherty, Eric S Simon, Rhonda D Cardin

Mol Pharm· January 2023

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Generation of a VeroE6 Pgp gene knock out cell line and its use in SARS-CoV-2 antiviral study.
Yuao Zhu, Joe Binder, Irina Yurgelonis, Devendra K Rai, Sarah Lazarro, Rhonda D Cardin

Antiviral Res· December 2022

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The CMV-encoded G protein-coupled receptors M33 and US28 play pleiotropic roles in immune evasion and alter host T cell responses.
Timothy M White, Cassandra M Bonavita, Brent A Stanfield, Helen E Farrell, Nicholas J Davis-Poynter, Rhonda D Cardin

Front Immunol· December 2022

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Immunisation Using Novel DNA Vaccine Encoding Virus Membrane Fusion Complex and Chemokine Genes Shows High Protection from HSV-2.
Ursula A Gompels, Fernando J Bravo, Sean Briggs, Shima Ameri, Rhonda D Cardin

Viruses· October 2022

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Development of a mouse salivary gland-derived mesenchymal cell line for immunological studies of murine cytomegalovirus.
Timothy M White, Brent A Stanfield, Cassandra M Bonavita, Jared S Rudd, Rhonda D Cardin

PLoS One· August 2022

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Characterization of murine cytomegalovirus infection and induction of calcification in Murine Aortic Vascular Smooth Muscle Cells (MOVAS).
Cassandra M Bonavita, Timothy M White, Brent A Stanfield, Rhonda D Cardin

J Virol Methods· November 2021

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Don't Go Breaking My Heart: MCMV as a Model for HCMV-Associated Cardiovascular Diseases.
Cassandra M Bonavita, Rhonda D Cardin

Pathogens· May 2021

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The R2 non-neuroinvasive HSV-1 vaccine affords protection from genital HSV-2 infections in a guinea pig model.
David I Bernstein, Rhonda D Cardin, Gregory A Smith, Gary E Pickard, Patricia J Sollars

NPJ Vaccines· November 2020

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Heart Dysfunction Following Long-Term Murine Cytomegalovirus Infection: Fibrosis, Hypertrophy, and Tachycardia.
Cassandra M Bonavita, Timothy M White, Joseph Francis, Rhonda D Cardin

Viral Immunol· April 2020

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A vaccine containing highly purified virus particles in adjuvant provides high level protection against genital infection and disease in guinea pigs challenged intravaginally with homologous and heterologous strains of herpes simplex virus type 2.
David I Bernstein, Christopher S Morello, Rhonda D Cardin, Fernando J Bravo, Kimberly A Kraynyak

Vaccine· January 2020

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Duration of protection from live attenuated vs. sub unit HSV-2 vaccines in the guinea pig model of genital herpes: Reassessing efficacy using endpoints from clinical trials.
David I Bernstein, Rhonda D Cardin, Derek A Pullum, Fernando J Bravo, Konstantin G Kousoulas

PLoS One· December 2019

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The Coxsackievirus and Adenovirus Receptor, a Required Host Factor for Recovirus Infection, Is a Putative Enteric Calicivirus Receptor.
Tibor Farkas, Kui Yang, Jacques Le Pendu, Joel D Baines, Rhonda D Cardin

J Virol· November 2019

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Intranasal nanoemulsion-adjuvanted HSV-2 subunit vaccine is effective as a prophylactic and therapeutic vaccine using the guinea pig model of genital herpes.
David I Bernstein, Rhonda D Cardin, Fernando J Bravo, Tarek Hamouda, Derek A Pullum

Vaccine· October 2019

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Successful application of prime and pull strategy for a therapeutic HSV vaccine.
David I Bernstein, Rhonda D Cardin, Fernando J Bravo, Sita Awasthi, Peiwen Lu

NPJ Vaccines· August 2019

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The HSV-1 live attenuated VC2 vaccine provides protection against HSV-2 genital infection in the guinea pig model of genital herpes.
David I Bernstein, Derek A Pullum, Rhonda D Cardin, Fernando J Bravo, David A Dixon

Vaccine· January 2019

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Tissue-specific control of latent CMV reactivation by regulatory T cells.
Maha Almanan, Jana Raynor, Allyson Sholl, Mei Wang, Claire Chougnet, Rhonda D Cardin

PLoS Pathog· August 2017

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Type 1 Interferons and NK Cells Limit Murine Cytomegalovirus Escape from the Lymph Node Subcapsular Sinus.
Helen E Farrell, Kimberley Bruce, Clara Lawler, Rhonda D Cardin, Nicholas J Davis-Poynter

PLoS Pathog· December 2016

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Replication-defective lymphocytic choriomeningitis virus vectors expressing guinea pig cytomegalovirus gB and pp65 homologs are protective against congenital guinea pig cytomegalovirus infection.
Rhonda D Cardin, Fernando J Bravo, Derek A Pullum, Klaus Orlinger, Elizabeth M Watson

Vaccine· April 2016

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