Publications by authors named "Rian Griffiths"

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Untargeted Metabolomics Identifies Faecal Filtrate-Derived Metabolites That Disrupt Metabolism and Confer Gut Barrier Cytoprotection.
Fatimah I Qassadi, Charlotte Johnson, Karen Robinson, Ruth Griffin, Christos Polytarchou, Rian L Griffiths

Int J Mol Sci· November 2025

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Untargeted Metabolomic Characterization of Glioblastoma Intra-Tumor Heterogeneity Using OrbiSIMS.
Wenshi He, Max K Edney, Simon M L Paine, Rian L Griffiths, David J Scurr

Anal Chem· April 2023

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Surface-sampling mass spectrometry to study proteins and protein complexes.
Kei F Carver Wong, Rebecca E Greatorex, Charlotte E Gidman, Sidrah Rahman, Rian L Griffiths

Essays Biochem· March 2023

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Probing Interkingdom Signaling Molecules via Liquid Extraction Surface Analysis-Mass Spectrometry.
Shaun N Robertson, Fadi Soukarieh, Thomas M White, Miguel Camara, Manuel Romero, Rian L Griffiths

Anal Chem· March 2023

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Identifying new biomarkers of aggressive Group 3 and SHH medulloblastoma using 3D hydrogel models, single cell RNA sequencing and 3D OrbiSIMS imaging.
Franziska Linke, James E C Johnson, Stefanie Kern, Christopher D Bennett, Anbarasu Lourdusamy, Rian L Griffiths

Acta Neuropathol Commun· January 2023

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Metabolic alterations in dairy cattle with lameness revealed by untargeted metabolomics of dried milk spots using direct infusion-tandem mass spectrometry and the triangulation of multiple machine learning models.
Wenshi He, Ana S Cardoso, Robert M Hyde, Martin J Green, David J Scurr, Rian L Griffiths

Analyst· November 2022

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Time resolved growth of (N)-polycyclic aromatic hydrocarbons in engine deposits uncovered with OrbiSIMS depth profiling.
Max K Edney, Wenshi He, Emily F Smith, Edward Wilmot, Jacqueline Reid, Rian L Griffiths

Analyst· August 2022

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Liquid Extraction Surface Analysis (LESA) High-Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS) Mass Spectrometry for In Situ Analysis of Intact Proteins.
Rian L Griffiths, Klaudia I Kocurek, Helen J Cooper

Methods Mol Biol· December 2020

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Native LESA TWIMS-MSI: Spatial, Conformational, and Mass Analysis of Proteins and Protein Complexes.
Oliver J Hale, Emma K Sisley, Rian L Griffiths, Iain B Styles, Helen J Cooper

J Am Soc Mass Spectrom· April 2020

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Comprehensive LESA Mass Spectrometry Imaging of Intact Proteins by Integration of Cylindrical FAIMS.
Rian L Griffiths, James W Hughes, Susan E Abbatiello, Michael W Belford, Iain B Styles

Anal Chem· February 2020

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Quantitative Imaging of Proteins in Tissue by Stable Isotope Labeled Mimetic Liquid Extraction Surface Analysis Mass Spectrometry.
Jana Havlikova, Elizabeth C Randall, Rian L Griffiths, John G Swales, Richard J A Goodwin

Anal Chem· November 2019

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Correction to Direct Mass Spectrometry Analysis of Protein Complexes and Intact Proteins up to >70 kDa from Tissue.
Rian L Griffiths, Albert Konijnenberg, Rosa Viner, Helen J Cooper

Anal Chem· July 2019

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Direct liquid extraction surface analysis mass spectrometry of cell wall lipids from mycobacteria: Salt additives for decreased spectral complexity.
Alexander N Conner, Jessie R Jarvis, Luke J Alderwick, Rian L Griffiths

Rapid Commun Mass Spectrom· July 2019

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Direct Mass Spectrometry Analysis of Protein Complexes and Intact Proteins up to >70 kDa from Tissue.
Rian L Griffiths, Albert Konijnenberg, Rosa Viner, Helen J Cooper

Anal Chem· June 2019

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Liquid Extraction Surface Analysis (LESA) Electron-Induced Dissociation and Collision-Induced Dissociation Mass Spectrometry of Small Molecule Drug Compounds.
Andrea F Lopez-Clavijo, Rian L Griffiths, Richard J A Goodwin, Helen J Cooper

J Am Soc Mass Spectrom· November 2018

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LESA MS Imaging of Heat-Preserved and Frozen Tissue: Benefits of Multistep Static FAIMS.
Rian L Griffiths, Anna L Simmonds, John G Swales, Richard J A Goodwin, Helen J Cooper

Anal Chem· November 2018

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Ambient ionisation mass spectrometry for in situ analysis of intact proteins.
Klaudia I Kocurek, Rian L Griffiths, Helen J Cooper

J Mass Spectrom· July 2018

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Ambient surface mass spectrometry-ion mobility spectrometry of intact proteins.
Rian L Griffiths, Klaudia I Kocurek, Helen J Cooper

Curr Opin Chem Biol· February 2018

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Raster-Mode Continuous-Flow Liquid Microjunction Mass Spectrometry Imaging of Proteins in Thin Tissue Sections.
Rian L Griffiths, Elizabeth C Randall, Alan M Race, Josephine Bunch, Helen J Cooper

Anal Chem· June 2017

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LESA FAIMS Mass Spectrometry for the Spatial Profiling of Proteins from Tissue.
Rian L Griffiths, Andrew J Creese, Alan M Race, Josephine Bunch, Helen J Cooper

Anal Chem· July 2016

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Direct Tissue Profiling of Protein Complexes: Toward Native Mass Spectrometry Imaging.
Rian L Griffiths, Helen J Cooper

Anal Chem· January 2016

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Liquid extraction surface analysis field asymmetric waveform ion mobility spectrometry mass spectrometry for the analysis of dried blood spots.
Rian L Griffiths, Alex Dexter, Andrew J Creese, Helen J Cooper

Analyst· October 2015

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Native Liquid Extraction Surface Analysis Mass Spectrometry: Analysis of Noncovalent Protein Complexes Directly from Dried Substrates.
Nicholas J Martin, Rian L Griffiths, Rebecca L Edwards, Helen J Cooper

J Am Soc Mass Spectrom· August 2015

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Liquid Extraction Surface Analysis Mass Spectrometry Coupled with Field Asymmetric Waveform Ion Mobility Spectrometry for Analysis of Intact Proteins from Biological Substrates.
Joscelyn Sarsby, Rian L Griffiths, Alan M Race, Josephine Bunch, Elizabeth C Randall

Anal Chem· July 2015

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Formal lithium fixation improves direct analysis of lipids in tissue by mass spectrometry.
Rian L Griffiths, Joscelyn Sarsby, Emily J Guggenheim, Alan M Race, Rory T Steven

Anal Chem· August 2013

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