Publications by authors named "Richard D Leduc"

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Aggregation-prone alpha-synuclein proteoforms and dysregulated molecular signatures in the vermiform appendix of synucleinopathy patients.
Ehraz Anis, Saima Zameer, Joshua Wierenga, Peipei Li, Jacek W Sikora, Richard D LeDuc

bioRxiv· October 2025

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Proteoform-predictor: Increasing the Phylogenetic Reach of Top-Down Proteomics.
Taojunfeng Su, Ryan T Fellers, Joseph B Greer, Richard D LeDuc, Paul M Thomas

J Proteome Res· April 2025

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How to maximize power for differential expression analysis in discovery omics through experimental design.
Brenden Dufault, Richard D LeDuc, René P Zahedi

Expert Rev Proteomics· January 2024

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Amyloid β Proteoforms Elucidated by Quantitative LC/MS in the 5xFAD Mouse Model of Alzheimer's Disease.
Soumya Kandi, Erika N Cline, Brianna M Rivera, Kirsten L Viola, Jiuhe Zhu, Richard D LeDuc

J Proteome Res· November 2023

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Anatomic nomenclature and 3-dimensional regional model of the human ovary: call for a new paradigm.
Kathleen E O'Neill, Jacqueline Y Maher, Monica M Laronda, Francesca E Duncan, Richard D LeDuc

Am J Obstet Gynecol· March 2023

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Creating a common language for the subanatomy of the ovary.
Elizabeth L Tsui, Kathleen E O'Neill, Richard D LeDuc, Ariella Shikanov, Veronica Gomez-Lobo

Biol Reprod· January 2023

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Middle-Down Mass Spectrometry Reveals Activity-Modifying Phosphorylation Barcode in a Class C G Protein-Coupled Receptor.
Ashley N Ives, Henry A Dunn, Hamid Samareh Afsari, Henrique Dos Santos Seckler, Max J Foroutan, Richard D LeDuc

J Am Chem Soc· December 2022

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ProSight Annotator: Complete control and customization of protein entries in UniProt XML files.
Joseph B Greer, Bryan P Early, Kenneth R Durbin, Steven M Patrie, Paul M Thomas, Richard D LeDuc

Proteomics· June 2022

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Proteomics Standards Initiative's ProForma 2.0: Unifying the Encoding of Proteoforms and Peptidoforms.
Richard D LeDuc, Eric W Deutsch, Pierre-Alain Binz, Ryan T Fellers, Anthony J Cesnik

J Proteome Res· April 2022

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Next-Generation Serology by Mass Spectrometry: Readout of the SARS-CoV-2 Antibody Repertoire.
Rafael D Melani, Benjamin J Des Soye, Jared O Kafader, Eleonora Forte, Michael Hollas, Richard D LeDuc

J Proteome Res· January 2022

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The Human Proteoform Atlas: a FAIR community resource for experimentally derived proteoforms.
Michael A R Hollas, Matthew T Robey, Ryan T Fellers, Richard D LeDuc, Paul M Thomas

Nucleic Acids Res· January 2022

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The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells.
Rafael D Melani, Vincent R Gerbasi, Lissa C Anderson, Jacek W Sikora, Timothy K Toby, Richard D LeDuc

Science· January 2022

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Next-generation Serology by Mass Spectrometry: Readout of the SARS-CoV-2 Antibody Repertoire.
Rafael D Melani, Benjamin J Des Soye, Jared O Kafader, Eleonora Forte, Michael Hollas, Richard D LeDuc

medRxiv· July 2021

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Using 10,000 Fragment Ions to Inform Scoring in Native Top-down Proteomics.
Ashley N Ives, Taojunfeng Su, Kenneth R Durbin, Bryan P Early, Henrique Dos Santos Seckler, Richard D LeDuc

J Am Soc Mass Spectrom· July 2020

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Proteomic analyses of decellularized porcine ovaries identified new matrisome proteins and spatial differences across and within ovarian compartments.
Nathaniel F Henning, Richard D LeDuc, Kelly A Even, Monica M Laronda

Sci Rep· December 2019

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Multidimensional Top-Down Proteomics of Brain-Region-Specific Mouse Brain Proteoforms Responsive to Cocaine and Estradiol.
Hae-Min Park, Rosalba Satta, Roderick G Davis, Young Ah Goo, Richard D LeDuc

J Proteome Res· November 2019

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A five-level classification system for proteoform identifications.
Lloyd M Smith, Paul M Thomas, Michael R Shortreed, Leah V Schaffer, Ryan T Fellers, Richard D LeDuc

Nat Methods· October 2019

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Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding.
Xiaoxiao Huang, Richard D LeDuc, Luca Fornelli, Alissa J Schunter, Richard L Bennett

J Biol Chem· August 2019

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Identification and Quantification of Proteoforms by Mass Spectrometry.
Leah V Schaffer, Robert J Millikin, Rachel M Miller, Lissa C Anderson, Ryan T Fellers, Richard D LeDuc

Proteomics· May 2019

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Accurate Estimation of Context-Dependent False Discovery Rates in Top-Down Proteomics.
Richard D LeDuc, Ryan T Fellers, Bryan P Early, Joseph B Greer, Daniel P Shams

Mol Cell Proteomics· April 2019

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The Value of Activated Ion Electron Transfer Dissociation for High-Throughput Top-Down Characterization of Intact Proteins.
Nicholas M Riley, Jacek W Sikora, Henrique S Seckler, Joseph B Greer, Ryan T Fellers, Richard D LeDuc

Anal Chem· July 2018

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Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk.
Ioanna Ntai, Luca Fornelli, Caroline J DeHart, Josiah E Hutton, Peter F Doubleday, Richard D LeDuc

Proc Natl Acad Sci U S A· April 2018

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ProForma: A Standard Proteoform Notation.
Richard D LeDuc, Veit Schwämmle, Michael R Shortreed, Anthony J Cesnik, Stefan K Solntsev

J Proteome Res· March 2018

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Top-Down Proteomics Enables Comparative Analysis of Brain Proteoforms Between Mouse Strains.
Roderick G Davis, Hae-Min Park, Kyunggon Kim, Joseph B Greer, Ryan T Fellers, Richard D LeDuc

Anal Chem· March 2018

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Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain.
Norelle C Wildburger, Thomas J Esparza, Richard D LeDuc, Ryan T Fellers, Paul M Thomas

Sci Rep· August 2017

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