Publications by authors named "Richard J Perrin"

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Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers.
Logan Brase, Shih-Feng You, Ricardo D'Oliveira Albanus, Jorge L Del-Aguila, Yaoyi Dai, Brenna C Novotny, Carolina Soriano-Tarraga, Taitea Dykstra, Maria Victoria Fernandez, John P Budde

Nat Commun· April 2023

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Longitudinal brain morphometry in Parkinson's disease clinical subtypes: Distinct signatures forecast behavioral change within subtypes.
Abdulmunaim M Eid, Sarah Grossen, Aaron Tanenbaum, Helen Hwang, Therese V Cash, Richard J Perrin

Parkinsonism Relat Disord· January 2026

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Plasma levels of an N-terminal tau fragment predict Alzheimer's and neurodegenerative disease biomarkers in autosomal dominant Alzheimer's disease.
Stephanie A Schultz, Yiwen Rao, Lei Liu, Beth Ostaszewski, Amirah K Anderson, Richard J Perrin

Alzheimers Dement· January 2026

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Biomarkers.
Nelly Joseph-Mathurin, Charles D Chen, Diana A Hobbs, Meng Jiang, Shaney Flores, Richard J Perrin

Alzheimers Dement· December 2025

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The Neighborhoods Study: Examining the social exposome in Alzheimer's disease and related dementias.
Grace C George, Sarah A Keller, Erin Abner, Sara Adar, Michael L Alosco, Richard J Perrin

Alzheimers Dement· November 2025

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The Knight Alzheimer Research Imaging (KARI) dataset: a comprehensive multimodal resource for exploring aging, preclinical, and symptomatic Alzheimer disease pathology.
David A Hoagey, Nicole S McKay, Nelly Joseph-Mathurin, Shaney Flores, Stephanie Doering, Richard J Perrin

Res Sq· November 2025

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Neuropathologic correlates of cognitive impairment in Alzheimer's disease with discordant CSF biomarker profiles: co-pathologies in focus.
Konstantinos Ioannou, Richard J Perrin, Khadidzha Abdullaieva, Marina Bluma, Antoine Leuzy

Acta Neuropathol· November 2025

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Mast cells regulate the brain-dura interface and CSF dynamics.
Tornike Mamuladze, Tiago H Zaninelli, Leon C D Smyth, Yue Wu, Daviti Abramishvili, Richard J Perrin

Cell· October 2025

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Novel differentially expressed genes and multiple biological pathways for Alzheimer's disease identified in brain tissue from African American donors.
Mark W Logue, Adam Labadorf, Nicholas K O'Neill, Dennis W Dickson, Brittany N Dugger, Richard J Perrin

Alzheimers Dement· October 2025

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Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers.
D Luke Fischer, Lea T Grinberg, Jared T Ahrendsen, Thomas G Beach, Kevin F Bieniek, Richard J Perrin

Alzheimers Dement· October 2025

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The relationship of soluble tau species with Alzheimer's disease amyloid plaque removal and tau pathology.
Eric M McDade, Nicolas R Barthélemy, Guoqiao Wang, Yan Li, Yuchen Cao, Richard J Perrin

Alzheimers Dement· September 2025

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The landscape of autosomal-dominant Alzheimer's disease: global distribution and age of onset.
Haiyan Liu, Thomas W Marsh, Xinyu Shi, Alan E Renton, Kevin M Bowling, Richard J Perrin

Brain· July 2025

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A route for cerebrospinal fluid flow through leptomeningeal arterial-venous overlaps enables macromolecule and fluid shunting.
Benjamin A Plog, Kyungdeok Kim, Daan Verhaege, Min Woo Kim, Zachary Papadopoulos, Richard J Perrin

Nat Neurosci· July 2025

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Regional effects of gantenerumab on neuroimaging biomarkers in the DIAN-TU-001 trial.
Austin McCullough, Charles D Chen, Brian A Gordon, Nelly Joseph-Mathurin, Clifford R Jack, Richard J Perrin

Alzheimers Dement· July 2025

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Systematic analysis of cellular cross-talk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer's disease.
Ricardo D'Oliveira Albanus, Gina M Finan, Logan Brase, Nicholas Sweeney, Tae Yeon Kim, Richard J Perrin

Sci Transl Med· July 2025

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Immunohistochemical evaluation of a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease.
Charles D Chen, Erin E Franklin, Yan Li, Nelly Joseph-Mathurin, Aime L Burns, Richard J Perrin

Acta Neuropathol· June 2025

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Novel early-onset Alzheimer-associated genes influence risk through dysregulation of glutamate, immune activation, and intracellular signaling pathways.
Joseph Bradley, Cyril Pottier, Eder Lucio da Fonseca, Jiji Thulaseedhara Kurup, Daniel Western, Richard J Perrin

Alzheimers Dement· June 2025

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A Comprehensive Study of Circulating Blood Linear RNA nominates and as novel causal genes and early-stage biomarkers for Parkinson's Disease.
Aleksandra Beric, Sarp Sahin, Santiago Sanchez, Zining Yang, Ravindra Kumar, Richard J Perrin

medRxiv· June 2025

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Ubiquitin-proteasome system in the different stages of dominantly inherited Alzheimer's disease.
Haiyan Liu, Quoc Bui, Jason Hassenstab, Brian A Gordon, Tammie L S Benzinger, Richard J Perrin

Alzheimers Dement· May 2025

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Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open-label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU trial.
Randall J Bateman, Yan Li, Eric M McDade, Jorge J Llibre-Guerra, David B Clifford, Richard J Perrin

Lancet Neurol· April 2025

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Depressive Symptoms and Amyloid Pathology.
Wietse A Wiels, Julie E Oomens, Sebastiaan Engelborghs, Chris Baeken, Christine A F von Arnim, Richard J Perrin

JAMA Psychiatry· March 2025

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Overview of Alzheimer's Disease Neuroimaging Initiative and future clinical trials.
Michael W Weiner, Shaveta Kanoria, Melanie J Miller, Paul S Aisen, Laurel A Beckett, Richard J Perrin

Alzheimers Dement· January 2025

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Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU Trial.
Randall J Bateman, Yan Li, Eric M McDade, Jorge J Llibre-Guerra, David B Clifford, Richard J Perrin

medRxiv· January 2025

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Genetic architecture of cerebrospinal fluid and brain metabolite levels and the genetic colocalization of metabolites with human traits.
Ciyang Wang, Chengran Yang, Daniel Western, Muhammad Ali, Yueyao Wang, Richard J Perrin

Nat Genet· December 2024

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Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer's disease.
Jiaxin Cindy Tu, Peter R Millar, Jeremy F Strain, Andrew Eck, Babatunde Adeyemo, Richard J Perrin

Netw Neurosci· December 2024

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Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer's disease.
Anna Hofmann, Lisa M Häsler, Marius Lambert, Stephan A Kaeser, Susanne Gräber-Sultan, Richard J Perrin

Nat Commun· November 2024

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