Publications by authors named "Ronald Hart"

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Ethanol induces neuroimmune dysregulation and soluble TREM2 generation in a human iPSC neuron, astrocyte, microglia triculture model.
Andrew J Boreland, Yara Abbo, Xindi Li, Alessandro C Stillitano, Siwei Zhang, Ronald P Hart

Alcohol· November 2025

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Perimenopausal state oestradiol to progesterone imbalance drives Alzheimer's risk via ERRα dysregulation and energy dyshomeostasis.
Jacquelyne Ka-Li Sun, Amy Zexuan Peng, Ronald P Hart, Karl Herrup, Deng Wu

Nat Commun· November 2025

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Beyond the synapse: Bassoon mutations drive epilepsy through Astrocyte-Neuron crosstalk.
Xindi Li, Ronald P Hart, Zhiping P Pang

Neurotherapeutics· October 2025

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Integrated single-cell multiomic profiling of caudate nucleus suggests key mechanisms in alcohol use disorder.
Nicholas C Green, Hongyu Gao, Xiaona Chu, Qiuyue Yuan, Patrick McGuire, Ronald P Hart

Nat Commun· October 2025

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Alpha-ketoglutarate mitigates insulin resistance and metabolic inflexibility in a mouse model of Ataxia-Telangiectasia.
Jacquelyne Ka-Li Sun, Ronald P Hart, Karl Herrup, Amy Zexuan Peng, Genper Chi-Ngai Wong

Nat Commun· October 2025

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Ethanol induces neuroimmune dysregulation and soluble TREM2 generation in a human iPSC neuron, astrocyte, microglia triculture model.
Andrew J Boreland, Yara Abbo, Xindi Li, Alessandro C Stillitano, Siwei Zhang, Ronald P Hart

bioRxiv· August 2025

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Creatine mitigates neurogenesis impairment caused by defective DcpS decapping.
Jun Yang, Geeta Palsule, Xinfu Jiao, Jaime S Messenger, Ronald P Hart

Sci Rep· May 2025

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Polygenic risk for alcohol use disorder affects cellular responses to ethanol exposure in a human microglial cell model.
Xindi Li, Jiayi Liu, Andrew J Boreland, Sneha Kapadia, Siwei Zhang, Ronald P Hart

Sci Adv· November 2024

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Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder.
Nick Green, Hongyu Gao, Xiaona Chu, Qiuyue Yuan, Patrick McGuire, Ronald P Hart

bioRxiv· October 2024

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Scaled and efficient derivation of loss-of-function alleles in risk genes for neurodevelopmental and psychiatric disorders in human iPSCs.
Hanwen Zhang, Ada McCarroll, Lilia Peyton, Sol Díaz de León-Guerrerro, Siwei Zhang, Ronald P Hart

Stem Cell Reports· October 2024

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Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanism.
Le Wang, Vincent R Mirabella, Rujia Dai, Xiao Su, Ranjie Xu, Ronald P Hart

Mol Psychiatry· June 2024

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Sustained type I interferon signaling after human immunodeficiency virus type 1 infection of human iPSC derived microglia and cerebral organoids.
Andrew J Boreland, Alessandro C Stillitano, Hsin-Ching Lin, Yara Abbo, Ronald P Hart

iScience· May 2024

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Biallelic NUDT2 variants defective in mRNA decapping cause a neurodevelopmental disease.
Ralf A Husain, Xinfu Jiao, J Christopher Hennings, Jan Giesecke, Geeta Palsule, Ronald P Hart

Brain· April 2024

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Upregulated GIRK2 Counteracts Ethanol-Induced Changes in Excitability and Respiration in Human Neurons.
Iya Prytkova, Yiyuan Liu, Michael Fernando, Isabel Gameiro-Ros, Dina Popova, Ronald P Hart

J Neurosci· April 2024

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A critical review of ethanol effects on neuronal firing: A metabolic perspective.
Dina Popova, Jacquelyne Sun, Hei-Man Chow, Ronald P Hart

Alcohol Clin Exp Res (Hoboken)· March 2024

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Scaled and Efficient Derivation of Loss of Function Alleles in Risk Genes for Neurodevelopmental and Psychiatric Disorders in Human iPSC.
Hanwen Zhang, Lilia Peyton, Ada McCarroll, Sol Díaz de León Guerrerro, Siwei Zhang, Ronald P Hart

bioRxiv· March 2024

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Upregulated GIRK2 counteracts ethanol-induced changes in excitability & respiration in human neurons.
Iya Prytkova, Yiyuan Liu, Michael Fernando, Isabel Gameiro-Ros, Dina Popova, Ronald P Hart

bioRxiv· January 2024

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5. Collaborative Study on the Genetics of Alcoholism: Functional genomics.
Isabel Gameiro-Ros, Dina Popova, Iya Prytkova, Zhiping P Pang, Yunlong Liu, Ronald P Hart

Genes Brain Behav· October 2023

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The Collaborative Study on the Genetics of Alcoholism: Overview.
Arpana Agrawal, Sarah J Brislin, Kathleen K Bucholz, Danielle Dick, Ronald P Hart

Genes Brain Behav· October 2023

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Dysregulated neuroimmune interactions and sustained type I interferon signaling after human immunodeficiency virus type 1 infection of human iPSC derived microglia and cerebral organoids.
Andrew J Boreland, Alessandro C Stillitano, Hsin-Ching Lin, Yara Abbo, Ronald P Hart

bioRxiv· October 2023

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Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex.
Iva Salamon, Yongkyu Park, Terezija Miškić, Janja Kopić, Paul Matteson, Ronald P Hart

Nat Commun· September 2023

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Metabolic rewiring and epigenetic reprogramming in leptin receptor-deficient db/db diabetic nephropathy mice.
Md Shahid Sarwar, David Cheng, Rebecca Mary Peter, Ahmad Shannar, Pochung Chou, Ronald P Hart

Eur J Pharmacol· August 2023

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The Amyloid Precursor Protein Modulates the Position and Length of the Axon Initial Segment.
Fulin Ma, Himanshu Akolkar, Jianquan Xu, Yang Liu, Dina Popova, Ronald P Hart

J Neurosci· March 2023

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Chronic alcohol metabolism results in DNA repair infidelity and cell cycle-induced senescence in neurons.
Jacquelyne Ka-Li Sun, Deng Wu, Genper Chi-Ngai Wong, Tsun-Ming Lau, Meigui Yang, Ronald P Hart

Aging Cell· February 2023

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Methods for shipping live primary cortical and hippocampal neuron cultures from postnatal mice.
Ferass M Sammoura, Dina Popova, Ayeshia Morris, Ronald P Hart, Jason R Richardson

Curr Res Neurobiol· December 2022

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