Publications by authors named "Roshan Kumar"

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Weaponising microbes for peace.
Shailly Anand, John E Hallsworth, James Timmis, Willy Verstraete, Arturo Casadevall, Juan Luis Ramos, Utkarsh Sood, Roshan Kumar, Princy Hira, Charu Dogra Rawat

Microb Biotechnol· June 2023

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A review on pyrimidine-based pharmacophore as a template for the development of hybrid drugs with anticancer potential.
Shivam Sharma, M Arockia Babu, Roshan Kumar, Thakur Gurjeet Singh, Ashish Ranjan Dwivedi, Kapil Kumar Goel, Bhupinder Kumar

Mol Divers· December 2025

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An update on current type 2 diabetes mellitus (T2DM) druggable targets and drugs targeting them.
Prerna Uniyal, Surbhi Panwar, Akanksha Bhatt, Arockia Babu Marianesan, Roshan Kumar, Bhupinder Kumar

Mol Divers· December 2025

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Antibiotic contamination and antimicrobial resistance dynamics in the urban sewage microbiome in India.
Deepjyoti Paul, Daizee Talukdar, Ramani Shyam Kapuganti, Vaishali Gupta, Lekshmi Narendrakumar, Pawan Kumar, Shalini Kumari, Roshan Kumar, Yashwant Kumar

Nat Commun· December 2025

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Iron addicted colorectal cancers exploit Heme-Complex II axis to resist oxidative cell death.
Chesta Jain, Muqit Essani, Roshan Kumar, Nupur K Das, Rashi Singhal

bioRxiv· November 2025

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Design and synthesis of new benzimidazole-hybrids as anti-microbial agents: exploring the mechanistic insights as DNA gyrase inhibitors via and based studies.
Anand Maurya, Upendra Kumar Patel, Punit Tiwari, Gaurav Joshi, Roshan Kumar

J Biomol Struct Dyn· October 2025

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Design and synthesis of tetrazole tethered quinazoline derivatives via azide-isocyanide cross-coupling reaction: Exploring the utility as anticancer agents via the SRC kinase inhibition in breast cancer.
Lang Zou, Umesh Prasad Yadav, Arockia Babu Marianesan, Roshan Kumar, Thakur Gurjeet Singh

Bioorg Chem· September 2025

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Dual inhibition of AXL and MER kinase: scope for lung and breast cancer therapeutics.
Balaji Dashrath Sathe, Pratibha Kumari, Hemant Kumar, Madhav Shivaji Mane, Ramesh Mudududdla, Roshan Kumar

Bioorg Chem· September 2025

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Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): the interplay of gut microbiome, insulin resistance, and diabetes.
Ankita Dua, Rashmi Kumari, Mona Singh, Roushan Kumar, Sunila Pradeep, Roshan Kumar

Front Med (Lausanne)· September 2025

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Race-related host and microbe transcriptomic signatures in triple-negative breast cancer.
Roshan Kumar, Susan Duyar-Ayerdi, Aishwarya Sundaresan, Vinodh Srinivasasainagendra, Chandra Sekhar Pedamallu

NPJ Breast Cancer· August 2025

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Exploring USFDA-Approved Imidazole-Based Small Molecules in Drug Discovery: A Mini Perspective.
Sonali Gupta, M Arockia Babu, Roshan Kumar, Thakur Gurjeet Singh, Anjali Goel, Kapil Kumar Goel, Bhupinder Kumar

Chem Biodivers· July 2025

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Design and synthesis of new 1,4-naphthoquinones appended sulfenylated thiazoles as cyclooxygenase II inhibitors: Exploring the utility in the development of anticancer agents.
Priyanka, Payal Rani, Anju Ranolia, Kiran, Gaurav Joshi, Roshan Kumar, Parvin Kumar

Bioorg Chem· July 2025

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A perspective on the synthetic methodologies and biological attributes of thiazole-hydrazone compounds: a medicinal chemistry-based investigation.
Pallishree Bhukta, Akash Verma, Roshan Kumar, Arockia Babu Marianesan, Suhas Ballal

Mol Divers· July 2025

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Hydrogen sulfide increases intracellular oxygen and regulates the HIF response.
Joseph Brake, David A Hanna, Roshan Kumar, Qianni Peng, Aaron P Landry

bioRxiv· July 2025

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Gut sulfide metabolism modulates behavior and brain bioenergetics.
Roshan Kumar, Delawrence J Sykes, Victor I Band, Megan L Schaller, Romel Patel

Proc Natl Acad Sci U S A· June 2025

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Design and development of new substituted pyrimidine hybrids with imidazole and triazole: Exploring utility as an anticancer agent via human topoisomerase-II and tubulin inhibition.
Umesh Prasad Yadav, Muhammad Yaseen, Shareen Singh, M Arockia Babu, Mashooq Ahmad Bhat, Roshan Kumar

Bioorg Chem· May 2025

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Gut sulfide metabolism modulates behavior and brain bioenergetics.
Roshan Kumar, Delawrence J Sykes, Victor I Band, Megan L Schaller, Romel Patel

bioRxiv· April 2025

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Isopropylmalate synthase regulatory domain removal abolishes feedback regulation at the expense of leucine homeostasis in plants.
Mohan Varghese, Roshan Kumar, Aprajita Sharma, Asif Lone, Jonathan Gershenzon

Plant Physiol· February 2025

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1,2,3-Triazole-tethered fluoroquinolone analogues with antibacterial potential: synthesis and cytotoxicity investigations.
Upendra Kumar Patel, Alka, Punit Tiwari, Ragini Tilak, Gaurav Joshi, Roshan Kumar

RSC Adv· January 2025

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A perspective on small molecules targeting the renin-angiotensin-aldosterone system and their utility in cardiovascular diseases: exploring the structural insights for rational drug discovery and development.
Nisha Bansal, Deepika Kathuria, Arockia M Babu, Sonia Dhiman, Sorabh Lakhanpal, Roshan Kumar, Bhupinder Kumar

RSC Med Chem· January 2025

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A Hybrid Deep Learning Model for Enhanced Structural Damage Detection: Integrating ResNet50, GoogLeNet, and Attention Mechanisms.
Vikash Singh, Anuj Baral, Roshan Kumar, Sudhakar Tummala, Mohammad Noori

Sensors (Basel)· November 2024

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Electrical spectroscopy of polaritonic nanoresonators.
Sebastián Castilla, Hitesh Agarwal, Ioannis Vangelidis, Yuliy V Bludov, David Alcaraz Iranzo, Roshan Krishna Kumar

Nat Commun· October 2024

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Exploring the Artificial Intelligence and Its Impact in Pharmaceutical Sciences: Insights Toward the Horizons Where Technology Meets Tradition.
Shruti Bharadwaj, Kumari Deepika, Asim Kumar, Shivani Jaiswal, Shaweta Miglani, Roshan Kumar, Bhupinder Kumar

Chem Biol Drug Des· October 2024

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A decade of pyridine-containing heterocycles in US FDA approved drugs: a medicinal chemistry-based analysis.
Ashish Ranjan Dwivedi, Shivani Jaiswal, Deepak Kukkar, Roshan Kumar, Thakur Gurjeet Singh, Bhupinder Kumar

RSC Med Chem· October 2024

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A rapid point-of-care population-scale dipstick assay to identify and differentiate SARS-CoV-2 variants in COVID-19-positive patients.
Deepjyoti Paul, Jyoti Verma, Shakti Kumar, Daizee Talukdar, Pradipta Jana, Lekshmi Narendrakumar, Roshan Kumar, Pramod Kumar Garg

Front Microbiol· October 2024

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An Unusual Case of a Stuck Catheter in a Sick Neonate.
Abhinav Aggarwal, Roshan Kumar, Alpas Anand, Preeti Gupta

Cureus· October 2024

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