Publications by authors named "Ruin Moaddel"

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Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin.
Michael Vreones, Maja Mustapic, Ruin Moaddel, Krishna A Pucha, Jacqueline Lovett, Douglas R Seals, Dimitrios Kapogiannis, Christopher R Martens

January 2023

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NMDAR inhibition-independent antidepressant actions of ketamine metabolites.
Panos Zanos, Ruin Moaddel, Patrick J Morris, Polymnia Georgiou, Jonathan Fischell, Greg I Elmer, Manickavasagom Alkondon, Peixiong Yuan, Heather J Pribut, Nagendra S Singh

Nature· May 2016

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Sirt6 prevents the age-related decline of HS through the control of one-carbon metabolism.
Noga Touitou, Liat Nahum, Sarit Feldman-Trabelsi, Matan Y Avivi, Miguel A Aon, Ruin Moaddel

Proc Natl Acad Sci U S A· November 2025

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A plasma proteomics-based candidate biomarker panel predictive of amyotrophic lateral sclerosis.
Ruth Chia, Ruin Moaddel, Justin Y Kwan, Memoona Rasheed, Paola Ruffo

Nat Med· October 2025

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SomaModules: A Pathway Enrichment Approach Tailored to SomaScan Data.
Julián Candia, Giovanna Fantoni, Francheska Delgado-Peraza, Nader Shehadeh, Toshiko Tanaka, Ruin Moaddel

J Proteome Res· September 2025

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SomaModules: a pathway enrichment approach tailored to SomaScan data.
Julián Candia, Giovanna Fantoni, Francheska Delgado-Peraza, Nader Shehadeh, Toshiko Tanaka, Ruin Moaddel

bioRxiv· August 2025

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Proteasome mutations associated with CANDLE syndrome cause altered neuronal development by dysregulating polyamine synthesis.
Clayton W Winkler, Benjamin Schwarz, Katie Williams, Sara Alehashemi, Simote T Foliaki, Ruin Moaddel

bioRxiv· August 2025

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Plasma longitudinal metabolic changes with acute maximal aerobic exercise and one-hour recovery.
William A Fountain, Stefano Donega, Nirad Banskota, Ruin Moaddel, Mona Patel

Front Mol Biosci· July 2025

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Choline and CCL22 Are Prognostic Blood Biomarkers for Hermansky-Pudlak Syndrome Pulmonary Fibrosis.
Muhammad Arif, Abhishek Basu, Ben Long G Zuo, Mei Xing G Zuo, Kevin J O'Brien, Ruin Moaddel

Am J Respir Cell Mol Biol· July 2025

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Publisher Correction: Senolytic effects of a modified Gingerenone A.
Ruin Moaddel, Chad Sanehira, Gregory Keyes, Chang-Yi Cui, Reza Ahmadkhaniha

NPJ Aging· June 2025

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Qualitative and quantitative lipidomic profiling of cardiolipin, oxidized cardiolipin, and monolysocardiolipin from human skeletal muscle by UPLC-Orbitrap-MS.
Zhi-Xin Yuan, Josephine M Egan, Arsun Bektas, Qu Tian, Alexey Lyashkov, Ruin Moaddel

Anal Chim Acta· May 2025

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Effects of In Vitro Hemolysis and Repeated Freeze-Thaw Cycles in Protein Abundance Quantification Using the SomaScan and Olink Assays.
Julián Candia, Giovanna Fantoni, Ruin Moaddel, Francheska Delgado-Peraza, Nader Shehadeh

J Proteome Res· May 2025

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Senolytic effects of a modified Gingerenone A.
Ruin Moaddel, Chad Sanehira, Gregory Keyes, Chang-Yi Cui, Reza Ahmadkhaniha

NPJ Aging· May 2025

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Effects of in vitro hemolysis and repeated freeze-thaw cycles in protein abundance quantification using the SomaScan and Olink assays.
Julián Candia, Giovanna Fantoni, Ruin Moaddel, Francheska Delgado-Peraza, Nader Shehadeh

bioRxiv· April 2025

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Serum Proteomic and Metabolomic Signatures of High Versus Low Physical Function in Octogenarians.
Ceereena Ubaida-Mohien, Ruin Moaddel, Sally Spendiff, Norah J MacMillan, Marie-Eve Filion

Aging Cell· March 2025

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Proteomic signature of HIV-associated subclinical left atrial remodeling and incident heart failure.
Tess E Peterson, Virginia S Hahn, Ruin Moaddel, Min Zhu, Sabina A Haberlen

Nat Commun· January 2025

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A Pilot Proteomic Analysis of Huntington's Disease by Functional Capacity.
Andrew McGarry, Ruin Moaddel

Brain Sci· January 2025

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Variability of 7K and 11K SomaScan Plasma Proteomics Assays.
Julián Candia, Giovanna Fantoni, Francheska Delgado-Peraza, Nader Shehadeh, Toshiko Tanaka, Ruin Moaddel

J Proteome Res· December 2024

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Ketamine metabolism via hepatic CYP450 isoforms contributes to its sustained antidepressant actions.
Thi Mai Loan Nguyen, Jean-Philippe Guilloux, Céline Defaix, Indira Mendez-David, Isabelle Etting, Ruin Moaddel

Neuropharmacology· November 2024

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A Phase 1 Assessment of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of (2R,6R)-Hydroxynorketamine in Healthy Volunteers.
Shruti M Raja, Jeffrey T Guptill, Michelle Mack, Marni Peterson, Stephen Byard, Ruin Moaddel

Clin Pharmacol Ther· November 2024

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Proteomic analysis of APOEε4 carriers implicates lipid metabolism, complement and lymphocyte signaling in cognitive resilience.
Keenan A Walker, Yang An, Abhay Moghekar, Ruin Moaddel, Michael R Duggan

Mol Neurodegener· October 2024

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Plasma metabolites in childhood Burkitt lymphoma cases and cancer-free controls in Uganda.
Jiaqi Huang, Hadijah Nabalende, M Constanza Camargo, Jacqueline Lovett, Isaac Otim, Ruin Moaddel

Metabolomics· June 2024

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Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome.
Brian Walitt, Komudi Singh, Samuel R LaMunion, Mark Hallett, Steve Jacobson, Ruin Moaddel

Nat Commun· February 2024

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Proteomic Signature of HIV-Associated Subclinical Left Atrial Remodeling and Incident Heart Failure.
Tess E Peterson, Virginia S Hahn, Ruin Moaddel, Min Zhu, Sabina A Haberlen

medRxiv· February 2024

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An exploratory metabolomic comparison of participants with fast or absent functional progression from 2CARE, a randomized, double-blind clinical trial in Huntington's disease.
Andrew McGarry, Krystal Hunter, John Gaughan, Peggy Auinger, Thomas N Ferraro, Ruin Moaddel

Sci Rep· January 2024

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Cerebrospinal fluid exploratory proteomics and ketamine metabolite pharmacokinetics in human volunteers after ketamine infusion.
Ruin Moaddel, Cristan A Farmer, Mani Yavi, Bashkim Kadriu, Min Zhu

iScience· December 2023

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Plant Protein but Not Animal Protein Consumption Is Associated with Frailty through Plasma Metabolites.
Toshiko Tanaka, Jayanta K Das, Yichen Jin, Qu Tian, Ruin Moaddel

Nutrients· September 2023

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