Publications by authors named "Ruud Brakenhoff"

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Explainable feature selection combining particle swarm optimisation with adaptive LASSO for MRI radiogenomics: Predicting HPV status in oropharyngeal cancer.
Milad Ahmadian, Zuhir Bodalal, Mary Adib, Seyed Sahand Mohammadi Ziabari, Paula Bos, Ruud H Brakenhoff

Comput Methods Programs Biomed· February 2026

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Post-processing steps improve generalisability and robustness of an MRI-based radiogenomic model for human papillomavirus status prediction in oropharyngeal cancer.
Milad Ahmadian, Zuhir Bodalal, Paula Bos, Roland M Martens, Georgios Agrotis, Ruud H Brakenhoff

Eur Radiol· December 2025

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Transcriptomic based prognostic model versus TNM 9th edition in HPV-positive oropharyngeal cancer.
Stefano Cavalieri, Ruud H Brakenhoff, C René Leemans, Frank Hoebers, Kathrin Scheckenbach

Oral Oncol· November 2025

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New insights into the genetic progression of cancer through longitudinal analysis of oral lesions.
Leon J Wils, Jos B Poell, Arjen Brink, Laura An Peferoen, Ilkay Evren, Ruud H Brakenhoff

J Pathol· October 2025

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Personalized treatment in HPV+ oropharynx cancer using genomic adjusted radiation dose.
Emily Ho, Loris De Cecco, Steven A Eschrich, Stefano Cavalieri, Geoffrey Sedor, Ruud H Brakenhoff

J Clin Invest· October 2025

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Loss of the Y Chromosome in Oral Potentially Premalignant Disorders Predicts Malignant Progression: An Integrative Cross-Species Multi-Cohort Bioinformatic Study.
Rui Han, Jos B Poell, Cristina Conde-Lopez, Tuula Salo, Ina Kurth, Ruud H Brakenhoff

Head Neck· October 2025

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An unexpected role of CLASP1 in radiation response and S-phase regulation of head and neck cancer cells.
Reinout H de Roest, Marijke Buijze, Myrthe Veth, Klaas de Lint, Govind Pai, Ruud H Brakenhoff

PLoS One· August 2025

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Profiling of psychoneurological symptoms in newly diagnosed head and neck cancer patients.
Joan C Medina, Femke Jansen, Birgit I Lissenberg-Witte, Remco de Bree, Ruud H Brakenhoff

Support Care Cancer· August 2025

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Prognostic gene expression signatures for HPV-negative head and neck squamous cell carcinoma.
Stefano Cavalieri, Ruud H Brakenhoff, C René Leemans, Frank J P Hoebers, Tito Poli

Radiother Oncol· July 2025

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The pan-cancer proteome atlas, a mass spectrometry-based landscape for discovering tumor biology, biomarkers, and therapeutic targets.
Jaco C Knol, Mengge Lyu, Franziska Böttger, Madalena Nunes Monteiro, Thang V Pham, Ruud H Brakenhoff

Cancer Cell· July 2025

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Strategies for early detection and detailed characterization of oral lesions and head and neck squamous cell carcinoma in Fanconi anemia patients.
Arnaud Beddok, Eunike Velleuer, Flore Sicre de Fontbrune, Ruud H Brakenhoff, Jean-Hugues Dalle

Cancer Lett· May 2025

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Return to Work Up to 5 Years After the End of Treatment Among Patients With Head and Neck Cancer.
Femke Jansen, Simone E J Eerenstein, Sara Arman, Birgit I Lissenberg-Witte, Jose A Hardillo, Ruud H Brakenhoff

JAMA Otolaryngol Head Neck Surg· April 2025

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Ferroptosis-Related Gene Signatures: Prognostic Role in HPV-Positive Oropharyngeal Squamous Cell Carcinoma.
Deborah Lenoci, Mara Serena Serafini, Marta Lucchetta, Stefano Cavalieri, Ruud H Brakenhoff

Cancers (Basel)· February 2025

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Author Correction: Hallmarks of a genomically distinct subclass of head and neck cancer.
Tara Muijlwijk, Irene H Nauta, Anabel van der Lee, Kari J T Grünewald, Arjen Brink, Ruud H Brakenhoff

Nat Commun· February 2025

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Richness for Tumor-Infiltrating B-Cells in the Oral Cancer Tumor Microenvironment Is a Prognostic Factor in Early-Stage Disease and Improves Outcome in Advanced-Stage Disease.
Irene H Nauta, Dennis N L M Nijenhuis, Sonja H Ganzevles, Pamela I Raaff, Jan Kloosterman, Ruud H Brakenhoff

Cancers (Basel)· January 2025

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Non-thermal plasma as promising anti-cancer therapy against bladder cancer by inducing DNA damage and cell cycle arrest.
Jojanneke Stoof, Zakaria Kalmoua, Ana Sobota, Ruud H Brakenhoff, Marijke Stigter

Sci Rep· January 2025

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TNM 8 staging system beyond p16: Double HPV/p16 status is superior to p16 alone in predicting outcome in oropharyngeal squamous cell carcinoma.
Christian von Buchwald, Kathrine Kronberg Jakobsen, Amanda-Louise Fenger Carlander, Sara Tous, Christian Grønhøj, Ruud H Brakenhoff

Eur J Cancer· November 2024

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Hallmarks of a genomically distinct subclass of head and neck cancer.
Tara Muijlwijk, Irene H Nauta, Anabel van der Lee, Kari J T Grünewald, Arjen Brink, Ruud H Brakenhoff

Nat Commun· October 2024

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Architectural dysplasia in surgical margins and the risk of local relapse in oral cancer.
Irene H Nauta, Laura A N Peferoen, Ruud H Brakenhoff, C René Leemans, Elisabeth Bloemena

J Oral Pathol Med· September 2024

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Secretome and immune cell attraction analysis of head and neck cancers.
Tara Muijlwijk, Niels E Wondergem, Fatima Ekhlas, Naomi Remkes, Dennis N L M Nijenhuis, Ruud H Brakenhoff

Cancer Immunol Immunother· September 2024

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Gemcitabine as chemotherapy of head and neck cancer in Fanconi anemia patients.
Anne M van Harten, Ronak Shah, D Vicky de Boer, Marijke Buijze, Maaike Kreft, Ruud H Brakenhoff

Oncogenesis· July 2024

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Circulating T cell status and molecular imaging may predict clinical benefit of neoadjuvant PD-1 blockade in oral cancer.
Niels E Wondergem, Iris H C Miedema, Rieneke van de Ven, Gerben J C Zwezerijnen, Pim de Graaf, Ruud H Brakenhoff

J Immunother Cancer· July 2024

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Immune cell topography of head and neck cancer.
Tara Muijlwijk, Dennis N L M Nijenhuis, Sonja H Ganzevles, Fatima Ekhlas, Carmen Ballesteros-Merino, Ruud H Brakenhoff

J Immunother Cancer· July 2024

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Genomic Engineering of Oral Keratinocytes to Establish In Vitro Oral Potentially Malignant Disease Models as a Platform for Treatment Investigation.
Leon J Wils, Marijke Buijze, Marijke Stigter-van Walsum, Arjen Brink, Britt E van Kempen, Ruud H Brakenhoff

Cells· April 2024

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Pharmacodynamics and biodistribution of [195mPt]cisplatin(CISSPECT®) in head and neck squamous cell carcinoma.
Reinout H de Roest, Marijke Stigter van Walsum, Karlijn van der Schilden, Ruud H Brakenhoff

EJNMMI Res· March 2024

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