Publications by authors named "S Jaag"

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Design, Synthesis, and Molecular Evaluation of SAr-Reactive N-(6-Fluoro-3-Nitropyridin-2-yl)Isoquinolin-3-Amines as Covalent USP7 Inhibitors Reveals an Unconventional Binding Mode.
Larissa N Ernst, Jason Stahlecker, Finn Mier, Ricardo A M Serafim, Valentin R Wydra, Simon J Jaag

Arch Pharm (Weinheim)· August 2025

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Multicolumn Two-Dimensional Liquid Chromatography Screening Platform for Stereopeptidomics and Application to Antimicrobial Peptide Polyene and Lipopeptide.
Cornelius Knappe, Simon J Jaag, Taulant Dema, Ruslan Jaufmann, Stephan Buckenmaier

Anal Chem· July 2025

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SAr Reactive Pyrazine Derivatives as p53-Y220C Cleft Binders with Diverse Binding Modes.
Theresa Klett, Jason Stahlecker, Martin Schwer, Simon J Jaag, Benedikt Masberg

Drug Des Devel Ther· July 2025

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Screening of Covalent Kinase Inhibitors Yields Hits for Cysteine Protease USP7 / HAUSP.
Larissa N Ernst, Simon J Jaag, Valentin R Wydra, Benedikt Masberg, Cornelius Knappe

Drug Des Devel Ther· May 2025

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Covalent Fragments Acting as Tyrosine Mimics for Mutant p53-Y220C Rescue by Nucleophilic Aromatic Substitution.
Theresa Klett, Jason Stahlecker, Simon Jaag, Benedikt Masberg, Cornelius Knappe

ACS Pharmacol Transl Sci· December 2024

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