Publications by authors named "S M Pickles"

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TDP-43 suppression of ATP8A2 cryptic splicing implicates phosphatidylserine-driven neuroinflammation in ALS/FTD.
James T O'Connor, Hui Qi Loo, Caiwei Guo, Sarah Pickles, Shea Sundali

bioRxiv· November 2025

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U7 small nuclear RNA splice-switching therapeutics for STMN2 and UNC13A in Amyotrophic Lateral Sclerosis.
Puja R Mehta, Tomas Solomon, Sarah Pickles, Peter Harley, Michela Barioglio

bioRxiv· November 2025

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TDP-43 Cryptic RNAs in Perry Syndrome: Differences across Brain Regions and TDP-43 Proteinopathies.
Sarah R Pickles, Jesus Gonzalez Bejarano, Anand Narayan, Lillian Daughrity, Candela Maroto Cidfuentes

Mov Disord· April 2025

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Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen Bereda, Sarah Pickles

Sci Transl Med· February 2024

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TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase.
Gang Liu, Tatt Jhong Haw, Malcolm R Starkey, Ashleigh M Philp, Stelios Pavlidis, Sophie Pickles

Nat Commun· November 2023

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