Publications by authors named "Sami Alzarea"

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TP53 apoptosis biomarkers in breast cancer.
Misbahuddin Rafeeq, Muhammad Afzal, Fahad A Al-Abbasi, Mustafa Zeyadi, Alaa Hamed Habib, Sami I Alzarea

Clin Chim Acta· January 2026

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Cubebin Niosomal Suspension Attenuates DMBA-Induced Breast Cancer Through the Involvement of Estrogen and Progesterone Receptors and Oxidative/Inflammatory/CA 15-3 Tumor Marker.
Sadaf Jamal Gilani, Ehssan Moglad, Muhammad Afzal, Misbahuddin Rafeeq, Alaa H Habib, Sami I Alzarea

J Biochem Mol Toxicol· January 2026

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A network pharmacology and in silico approach to target NEU1-mediated microglial activation in neuroinflammation: Validation in an LPS-induced mouse model.
Sami I Alzarea, Omar Awad Alsaidan, Sumera Qasim, Hassan H Alhassan, Abdulaziz Ibrahim Alzarea

Comput Biol Med· December 2025

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Galectin-3 as a cardiac biomarker.
Asif Ahmad Bhat, Yahia Alghazwani, Kumarappan Chidambaram, M M Rekha, Samir Sahoo, Sami I Alzarea

Clin Chim Acta· December 2025

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An integrative computational approach for identification of NLRP3 inhibitors through machine learning, docking, dynamics and DFT analysis.
Sami I Alzarea

Sci Rep· December 2025

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'Laminarin-Based nanocarriers: a paradigm shift in biopolymer engineering for advanced drug delivery and therapeutics'.
Devesh U Kapoor, Devendra Vaishnav, Sanjesh Kumar, Bhupendra G Prajapati, Omar Awad Alsaidan, Sami I Alzarea

J Biomater Sci Polym Ed· November 2025

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Identification of novel neuraminidase 1 modulators as potential therapeutics for Alzheimer's disease using virtual screening and molecular dynamics simulations.
Sami I Alzarea

Sci Rep· November 2025

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Drug-induced headache reports: a comprehensive disproportionality and time-to-onset pharmacovigilance study using the FAERS database (2018-2024).
Abdulaziz Ibrahim Alzarea, Azfar Athar Ishaqui, Muhammad Bilal Maqsood, Abdullah Salah Alanazi, Aseel Awad Alsaidan, Sami I Alzarea

Front Pain Res (Lausanne)· November 2025

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Advancing β-Glucan-Based Immunomodulation and Nanotherapeutic Strategies for Cancer Biotherapy.
Neelakanta Sarvashiva Kiran, Darshini Subramaniam, Chandrashekar Yashaswini, Ankita Chatterjee, Bhupendra Prajapati, Sami I Alzarea

Cancer Biother Radiopharm· November 2025

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Evaluating AI performance in infectious disease education: a comparative analysis of ChatGPT, Google Bard, Perplexity AI, Microsoft Copilot, and Meta AI.
Abdulaziz Ibrahim Alzarea, Azfar Athar Ishaqui, Muhammad Bilal Maqsood, Abdullah Salah Alanazi, Aseel Awad Alsaidan, Sami I Alzarea

Front Med (Lausanne)· October 2025

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Barbigerone against Lipopolysaccharide-Induced Memory Deficit in Rats via Alteration of Inflammatory and Oxidative Stress Pathway: , Molecular Docking and Molecular Dynamics Simulations Study.
Muhammad Shahid Nadeem, Jalaluddin Azam Khan, Fahad A Al-Abbasi, May M Alqurashi, Azizah Salim Bawadood, Sami I Alzarea

CNS Neurol Disord Drug Targets· September 2025

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In silico and evaluation of erucic acid against pentylenetetrazole-induced seizures in mice by modulating oxidative stress, neurotransmitters and neuroinflammation markers.
Sami I Alzarea, Muhammad Afzal, Ehssan Moglad, Hassan H Alhassan, Abdulaziz Ibrahim Alzarea

Nutr Neurosci· September 2025

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Exploring the therapeutic potential of aloenin-loaded nanogel for imiquimod-induced psoriasis-like skin conditions: In vitro and in vivo assessment.
Sadaf Jamal Gilani, Ehssan Moglad, Muhammad Afzal, Misbahuddin Rafeeq, Alaa Hamed Habib, Sami I Alzarea

J Pharmacol Exp Ther· September 2025

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Non-coding RNA-mediated gene regulation in Alzheimer's disease pathogenesis: molecular insights and emerging innovations.
Sami I Alzarea

Saudi Pharm J· September 2025

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Creatine kinase in prostate cancer: A biosensor-driven diagnostic paradigm.
Surya Nath Pandey, Ehssan Moglad, Gaurav Gupta, H Malathi, Laxmidhar Maharana, Sami I Alzarea

Clin Chim Acta· August 2025

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Design, synthesis, and apoptotic antiproliferative efficacy of new quinazoline/1,3,4-oxadiazole-2-thione derived EGFR/HER-2 dual inhibitors with anti-breast cancer activity.
Hesham A M Gomaa, Mohamed E Shaker, Sami I Alzarea, Tariq G Alsahli, Abdullah Salah Alanazi

RSC Med Chem· July 2025

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Integrating Quality by Design (QbD) in Phytosomal Drug Delivery: A New Era in Precision Phytotherapy.
Sumant Kumar, Omar Awad Alsaidan, Sami I Alzarea, Akshay Kumar, Suresh Babu Kondaveeti

AAPS PharmSciTech· July 2025

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Tumor-educated platelets in lung cancer.
Md Sadique Hussain, Ehssan Moglad, Ahsas Goyal, M M Rekha, Girish Chandra Sharma, Sami I Alzarea

Clin Chim Acta· June 2025

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Preventive effect of acemannan on DMBA-induced mouse skin tumorigenesis by modulating inflammatory cytokines and apoptosis pathways: molecular docking and molecular dynamic simulation approaches.
Abdulaziz Ibrahim Alzarea, Ameeduzzafar Zafar, Omar Awad Alsaidan, Abdullah Salah Alanazi, Sami Ibrahim Alzarea

Int J Biol Macromol· June 2025

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Translational potential of GADD45α: biomarker and therapeutic target in age-associated neurodegeneration and longevity.
Imran Kazmi, Fahad A Al-Abbasi, Mustafa Zeyadi, Misbahuddin Rafeeq, Alaa Hamed Habib, Sami I Alzarea

Biogerontology· June 2025

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ATM and p53 in aging and cancer: a double-edged sword in genomic integrity.
Surya Nath Pandey, Muhammad Afzal, Jyoti Uikey, Subbulakshmi Ganesan, Swati Mishra, Sami I Alzarea

Biogerontology· May 2025

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Design, synthesis, and biological investigation of new thiazole-based derivatives as multi-targeted inhibitors endowed with antiproliferative, antioxidant, and antibacterial properties.
Hesham A M Gomaa, Asmaa M Atta, Mohamed E Shaker, Sami I Alzarea, Tariq G Alsahli

Front Chem· May 2025

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Neuraminidase as a novel therapeutic management strategy for Alzheimer's disease: evidenced through molecular docking, molecular dynamic simulation and gene expression analysis.
Sami I Alzarea, Omar Awad Alsaidan, Hassan H Alhassan, Abdulaziz Ibrahim Alzarea, Tariq G Alsahli

Front Chem· May 2025

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miR-210: A non-invasive biomarker for hypoxia-driven lung cancer diagnosis and therapy.
Ahsas Goyal, Muhammad Afzal, Kavita Goyal, Suhas Ballal, Girish Chandra Sharma, Sami I Alzarea

Clin Chim Acta· April 2025

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Parthanatos and apoptosis: unraveling their roles in cancer cell death and therapy resistance.
Gaurav Gupta, Muhammad Afzal, Ehssan Moglad, Ahsas Goyal, Waleed Hassan Almalki, Sami I Alzarea

EXCLI J· March 2025

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