Publications by authors named "Samir Hanash"

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Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids.
Yi-Jia Li, Johannes Francois Fahrmann, Maryam Aftabizadeh, Qianqian Zhao, Satyendra C Tripathi, Chunyan Zhang, Yuan Yuan, David Ann, Samir Hanash, Hua Yu

May 2022

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SMAGS-LASSO: A Novel Feature Selection Method for Sensitivity Maximization in Early Cancer Detection.
Hamid Khoshfekr Rudsari, Sara Khorami-Sarvestani, Johannes F Fahrmann, James P Long, Samir Hanash

Cancer Epidemiol Biomarkers Prev· December 2025

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Lung adenocarcinoma surfaceome remodeling with EGFR inhibitors uncovers placental alkaline phosphatase as a target for combination therapy.
Yihui Chen, Rongzhang Dou, Monica J Hong, Hanwen Xu, Jody Vykoukal, Samir M Hanash

Cell Rep Med· December 2025

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Vesicle-mediated mitochondrial clearance presents an actionable metabolic vulnerability in triple-negative breast cancer.
Jody Vykoukal, Yihui Chen, Mingxin Zuo, Riccardo Ballarò, Monica J Hong, Samir Hanash

Cell Rep Med· December 2025

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The LEAP Study: A Multicenter Biospecimen and Imaging Resource for Lung Cancer Screening.
Jennifer B Dennison, Sebastien Gendarme, Nicole M Kettner, Myrna C B Godoy, Julie V Philley, Samir Hanash

Cancer Epidemiol Biomarkers Prev· November 2025

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Validation of a blood test for multi-cancer risk stratification in a lung cancer screening cohort.
Johannes F Fahrmann, Ehsan Irajizad, Hamid Rudsari, Jody Vykoukal, Iakovos Toumazis, Samir Hanash

medRxiv· November 2025

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Protocol for isolating patient-derived ascites cells and extracellular vesicles from gastric cancer peritoneal metastases.
Yibo Fan, Jody V Vykoukal, Shumei Song, Melissa Pool Pizzi, Gengyi Zou, Samir Hanash

STAR Protoc· October 2025

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Long-chain sulfatide enrichment is an actionable metabolic vulnerability in intraductal papillary mucinous neoplasm (IPMN)-associated pancreatic cancers.
Yihui Chen, Riccardo Ballarò, Marta Sans, Fredrik Ivar Thege, Mingxin Zuo, Samir M Hanash

Gut· September 2025

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Cyst fluid proteins stratify malignant risk of intraductal papillary mucinous neoplasm of the pancreas.
Chunliang Liu, Amber Mosley, Ehsan Irajizad, Michele Yip-Schneider, Huangbing Wu, Samir Hanash

Cancer Lett· August 2025

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Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers.
Madelaine S Theardy, Mitsunobu Takeda, Alexey Sorokin, Shuaitong Chen, Zecheng Yang, Samir Hanash

Cell Rep Med· August 2025

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KAP1 promotes gastric adenocarcinoma progression by activating Hippo/YAP1 signaling via binding to HNRNPAB.
Shumei Song, Yibo Fan, Gengyi Zou, Longfei Huo, Janani Kumar, Samir Hanash

Cancer Lett· July 2025

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Integrated Metabolomics and Spatial Transcriptomics of Cystic Pancreatic Cancer Precursors Reveals Dysregulated Polyamine Metabolism as a Biomarker of Progression.
Ricardo A León-Letelier, Yihui Chen, Rongzhang Dou, Ehsan Irajizad, Michele T Yip-Schneider, Samir Hanash

Clin Cancer Res· June 2025

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Spatial and multiomics analysis of human and mouse lung adenocarcinoma precursors reveals TIM-3 as a putative target for precancer interception.
Bo Zhu, Pingjun Chen, Muhammad Aminu, Jian-Rong Li, Junya Fujimoto, Samir Hanash

Cancer Cell· June 2025

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Citrullinated ENO1 Vaccine Enhances PD-1 Blockade in Mice Implanted with Murine Triple-Negative Breast Cancer Cells.
Ricardo A León-Letelier, Alejandro M Sevillano-Mantas, Yihui Chen, Soyoung Park, Jody Vykoukal, Samir Hanash

Vaccines (Basel)· June 2025

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Impact of Comorbidities on the Mortality Benefits of Lung Cancer Screening: A Post-Hoc Analysis of the PLCO and NLST Trials.
Sebastien Gendarme, Ehsan Irajizad, James P Long, Johannes F Fahrmann, Jennifer B Dennison, Samir M Hanash

J Thorac Oncol· May 2025

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Elevated levels of circulating microbial-associated uremic toxins are associated with metastatic duodenopancreatic neuroendocrine tumors in patients with Multiple Endocrine Neoplasia Type 1.
Riccardo Ballarò, Amanda R Wasylishen, Carolina R C Pieterman, Courtney Olsen, Ehsan Irajizad, Samir M Hanash

Cancer Lett· April 2025

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Grape-Pi: graph-based neural networks for enhanced protein identification in proteomics pipelines.
Chunhui Gu, Seyyed Mahmood Ghasemi, Yining Cai, Johannes F Fahrmann, James P Long, Samir Hanash

Bioinform Adv· April 2025

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A Novel Sensitivity Maximization at a Given Specificity Method for Binary Classifications.
Seyyed Mahmood Ghasemi, Chunhui Gu, Johannes F Fahrmann, Samir Hanash, Kim-Anh Do

Cancer Prev Res (Phila)· March 2025

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Lead time trajectory of blood-based protein biomarkers for detection of pancreatic cancer based on repeat testing.
Johannes F Fahrmann, Michele Yip-Schneider, Jody Vykoukal, Rachelle Spencer, Jennifer B Dennison, Samir Hanash

Cancer Lett· March 2025

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Antibiotic-induced loss of gut microbiome metabolic output correlates with clinical responses to CAR T-cell therapy.
Rishika Prasad, Abdur Rehman, Lubna Rehman, Faezeh Darbaniyan, Viktoria Blumenberg, Samir Hanash

Blood· February 2025

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Exosomal Galectin-3 promotes peritoneal metastases in gastric adenocarcinoma via microenvironment alterations.
Yibo Fan, Shumei Song, Melissa Pool Pizzi, Gengyi Zou, Jody V Vykoukal, Samir Hanash

iScience· January 2025

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Glycosylation in cancer as a source of biomarkers.
Sara Khorami-Sarvestani, Samir M Hanash, Johannes F Fahrmann, Ricardo A León-Letelier, Hiroyuki Katayama

Expert Rev Proteomics· November 2024

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Validation of a prognostic blood-based sphingolipid panel for men with localized prostate cancer followed on active surveillance.
Justin R Gregg, Lisa Newcomb, Ranran Wu, Jennifer Dennison, John W Davis, Samir Hanash

Biomark Res· November 2024

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Biomarker trajectory for earlier detection of lung cancer.
Ehsan Irajizad, Johannes F Fahrmann, Iakovos Toumazis, Jody Vykoukal, Jennifer B Dennison, Samir Hanash

EBioMedicine· October 2024

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Designing Rigorous and Efficient Clinical Utility Studies for Early Detection Biomarkers.
Yingye Zheng, Paul D Wagner, Amit G Singal, Samir M Hanash, Sudhir Srivastava

Cancer Epidemiol Biomarkers Prev· September 2024

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Benchmarking lung cancer screening programmes with adaptive screening frequency against the optimal screening schedules derived from the ENGAGE framework: a comparative microsimulation study.
Mehdi Hemmati, Sayaka Ishizawa, Rafael Meza, Edwin Ostrin, Samir M Hanash

EClinicalMedicine· August 2024

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