Publications by authors named "Sara A Byron"

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Genome-wide analysis of aberrant position and sequence of plasma DNA fragment ends in patients with cancer.
Karan K Budhraja, Bradon R McDonald, Michelle D Stephens, Tania Contente-Cuomo, Havell Markus, Maria Farooq, Patricia F Favaro, Sydney Connor, Sara A Byron, Jan B Egan

Sci Transl Med· January 2023

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Challenges in the return of molecular tumor profiling results.
Heinz-Josef Lenz, David W Craig, Kevin C Johnson, Roel Verhaak, Oindrila Bhattacharyya, Sara A Byron

J Natl Cancer Inst· September 2025

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Retrospective Comparison of Targeted Anticancer Drugs Predicted by the CNS-TAP Tool Versus Those Selected by a Molecularly Driven Tumor Board in Children With DIPG.
Holly J Roberts, Karthik Ravi, Bernard L Marini, Allison Schepers, Cassie Kline, Sara A Byron

J Pediatr Hematol Oncol· January 2025

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Genomic analysis across 53 canine cancer types reveals novel mutations and high clinical actionability potential.
Sharadha Sakthikumar, Manisha Warrier, Derick Whitley, Salvatore Facista, Jonathan Adkins, Sara A Byron

Vet Comp Oncol· March 2024

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Molecular-guided therapy for the treatment of patients with relapsed and refractory childhood cancers: a Beat Childhood Cancer Research Consortium trial.
Giselle L Saulnier Sholler, Genevieve Bergendahl, Elizabeth C Lewis, Jacqueline Kraveka, William Ferguson, Sara A Byron

Genome Med· February 2024

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Standing in the canine precision medicine knowledge gap: Improving annotation of canine cancer genomic biomarkers through systematic comparative analysis of human cancer mutations in COSMIC.
Sharadha Sakthikumar, Salvatore Facista, Derick Whitley, Sara A Byron, Zeeshan Ahmed

Vet Comp Oncol· September 2023

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A pilot study of genomic-guided induction therapy followed by immunotherapy with difluoromethylornithine maintenance for high-risk neuroblastoma.
Jacqueline M Kraveka, Elizabeth C Lewis, Genevieve Bergendahl, William Ferguson, Javier Oesterheld, Sara A Byron

Cancer Rep (Hoboken)· November 2022

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Genomic and Transcriptomic Analysis of Relapsed and Refractory Childhood Solid Tumors Reveals a Diverse Molecular Landscape and Mechanisms of Immune Evasion.
Sara A Byron, William P D Hendricks, Abhinav B Nagulapally, Jacqueline M Kraveka, William S Ferguson

Cancer Res· December 2021

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Identifying treatment options for BRAFV600 wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial.
Patricia M LoRusso, Aleksandar Sekulic, Jeffrey A Sosman, Winnie S Liang, John Carpten, Sara A Byron

PLoS One· September 2021

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Temporospatial genomic profiling in glioblastoma identifies commonly altered core pathways underlying tumor progression.
Mylan R Blomquist, Shannon Fortin Ensign, Fulvio D'Angelo, Joanna J Phillips, Michele Ceccarelli, Sara A Byron

Neurooncol Adv· June 2020

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Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas.
Michael E Berens, Anup Sood, Jill S Barnholtz-Sloan, John F Graf, Sanghee Cho, Sara A Byron

PLoS One· March 2020

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A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium.
Sabine Mueller, Payal Jain, Winnie S Liang, Lindsay Kilburn, Cassie Kline, Sara A Byron

Int J Cancer· October 2019

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Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer.
Olena M Vaske, Isabel Bjork, Sofie R Salama, Holly Beale, Avanthi Tayi Shah, Sara A Byron

JAMA Netw Open· October 2019

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E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases.
Hani M Babiker, Sara A Byron, William P D Hendricks, William F Elmquist, Gautham Gampa

Invest New Drugs· August 2019

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Genomics-Enabled Precision Medicine for Cancer.
Alison Roos, Sara A Byron

Cancer Treat Res· June 2019

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Bcl-2 inhibitors enhance FGFR inhibitor-induced mitochondrial-dependent cell death in FGFR2-mutant endometrial cancer.
Leisl M Packer, Samantha J Stehbens, Vanessa F Bonazzi, Jennifer H Gunter, Robert J Ju, Sara A Byron

Mol Oncol· April 2019

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Leveraging Spatial Variation in Tumor Purity for Improved Somatic Variant Calling of Archival Tumor Only Samples.
Rebecca F Halperin, Winnie S Liang, Sidharth Kulkarni, Erica E Tassone, Jonathan Adkins, Sara A Byron

Front Oncol· March 2019

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Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma.
Sara A Byron, Nhan L Tran, Rebecca F Halperin, Joanna J Phillips, John G Kuhn

Clin Cancer Res· January 2018

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A prospective pilot study of genome-wide exome and transcriptome profiling in patients with small cell lung cancer progressing after first-line therapy.
Glen J Weiss, Sara A Byron, Jessica Aldrich, Ashish Sangal, Heather Barilla

PLoS One· September 2017

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FGFR2 mutations are associated with poor outcomes in endometrioid endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study.
Yvette W Jeske, Shamshad Ali, Sara A Byron, Feng Gao, Robert S Mannel

Gynecol Oncol· May 2017

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Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer.
Marc A Becker, Yasir H Ibrahim, Annabell S Oh, Dedra H Fagan, Sara A Byron

PLoS One· August 2016

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Translating RNA sequencing into clinical diagnostics: opportunities and challenges.
Sara A Byron, Kendall R Van Keuren-Jensen, David M Engelthaler, John D Carpten, David W Craig

Nat Rev Genet· May 2016

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An integrated framework for reporting clinically relevant biomarkers from paired tumor/normal genomic and transcriptomic sequencing data in support of clinical trials in personalized medicine.
Sara Nasser, Ahmet A Kurdolgu, Tyler Izatt, Jessica Aldrich, Megan L Russell, Sara A Byron

Pac Symp Biocomput· April 2016

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Toward precision medicine in glioblastoma: the promise and the challenges.
Michael D Prados, Sara A Byron, Nhan L Tran, Joanna J Phillips, Annette M Molinaro

Neuro Oncol· August 2015

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The N550K/H mutations in FGFR2 confer differential resistance to PD173074, dovitinib, and ponatinib ATP-competitive inhibitors.
Sara A Byron, Huaibin Chen, Andreas Wortmann, David Loch, Michael G Gartside

Neoplasia· August 2013

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