Publications by authors named "Sarah Dimeloe"

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Vitamin D and Immune Regulation: Antibacterial, Antiviral, Anti-Inflammatory.
Emma L Bishop, Aiten Ismailova, Sarah Dimeloe, Martin Hewison, John H White

JBMR Plus· January 2021

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mTOR activity and metabolic reprogramming of CD8+ T cells is impaired under hypoxia and within the multiple myeloma bone marrow.
Taylor Fulton-Ward, Nancy Gudgeon, Isaac Thirlwell, Emma L Bishop, Bryan Marzullo, Sarah Dimeloe

Blood Adv· December 2025

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Immunometabolic profiling of T cells in response to prolonged moderate intensity cycling in humans.
Fendi Pradana, Jonathan P Barlow, Jack Shayler, Sarah K Dimeloe, Nancy Gudgeon

Exerc Immunol Rev· December 2025

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NAD + metabolism and function in innate and adaptive immune cells.
Rebecca Mann, Victoria Stavrou, Sarah Dimeloe

J Inflamm (Lond)· August 2025

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Iron deficiency causes aspartate-sensitive dysfunction in CD8 T cells.
Megan R Teh, Nancy Gudgeon, Joe N Frost, Linda V Sinclair, Alastair L Smith, Sarah Dimeloe

Nat Commun· June 2025

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Metabolic Characterization of Deceased Donor Kidneys Undergoing Hypothermic Machine Perfusion Before Transplantation Using C-enriched Glucose.
Kamlesh Patel, Jay Nath, Thomas Smith, Tom Darius, Alpesh Thakker, Sarah Dimeloe

Transplant Direct· January 2025

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IL-7 promotes integrated glucose and amino acid sensing during homeostatic CD4 T cell proliferation.
Seema Bachoo, Nancy Gudgeon, Rebecca Mann, Victoria Stavrou, Emma L Bishop, Sarah Dimeloe

Cell Rep· January 2025

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Proteomic analysis reveals dysregulation of peripheral blood neutrophils in patients with Multiple Sclerosis.
Katie J Smith, Zachary Lim, Sonja Vermeren, Veronique E Miron, Sarah Dimeloe

Clin Exp Immunol· January 2025

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Salmonella cancer therapy metabolically disrupts tumours at the collateral cost of T cell immunity.
Alastair Copland, Gillian M Mackie, Lisa Scarfe, Elizabeth Jinks, David A J Lecky, Sarah Dimeloe

EMBO Mol Med· December 2024

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The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival.
Vesna S Stanulović, Shorog Al Omair, Michelle A C Reed, Jennie Roberts, Sandeep Potluri, Sarah Dimeloe

Haematologica· November 2024

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TNF-α signals through ITK-Akt-mTOR to drive CD4 T cell metabolic reprogramming, which is dysregulated in rheumatoid arthritis.
Emma L Bishop, Nancy Gudgeon, Taylor Fulton-Ward, Victoria Stavrou, Jennie Roberts, Sarah Dimeloe

Sci Signal· April 2024

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Uptake of long-chain fatty acids from the bone marrow suppresses CD8+ T-cell metabolism and function in multiple myeloma.
Nancy Gudgeon, Hannah Giles, Emma L Bishop, Taylor Fulton-Ward, Cristina Escribano-Gonzalez, Sarah Dimeloe

Blood Adv· October 2023

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Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity.
Benjamin J Jenkins, Julianna Blagih, Fernando M Ponce-Garcia, Mary Canavan, Nancy Gudgeon, Sarah K Dimeloe

Cell Metab· July 2023

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Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4 T cell.
Louise S Matheson, Georg Petkau, Beatriz Sáenz-Narciso, Vanessa D'Angeli, Jessica McHugh, Sarah Dimeloe

Sci Rep· November 2022

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Succinate uptake by T cells suppresses their effector function via inhibition of mitochondrial glucose oxidation.
Nancy Gudgeon, Haydn Munford, Emma L Bishop, James Hill, Taylor Fulton-Ward, Sarah Dimeloe

Cell Rep· August 2022

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1,25-Dihydroxyvitamin D3 suppresses CD4 T-cell effector functionality by inhibition of glycolysis.
Emma L Bishop, Nancy H Gudgeon, Gillian M Mackie, Daniel Chauss, Jennie Roberts, Sarah Dimeloe

Immunology· July 2022

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Autoimmune disease and interconnections with vitamin D.
Jane Fletcher, Emma L Bishop, Stephanie R Harrison, Amelia Swift, Sheldon C Cooper, Sarah K Dimeloe

Endocr Connect· March 2022

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Control of T Cell Metabolism by Cytokines and Hormones.
Emma L Bishop, Nancy Gudgeon, Sarah Dimeloe

Front Immunol· September 2021

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The Induction of Alpha-1 Antitrypsin by Vitamin D in Human T Cells Is TGF-β Dependent: A Proposed Anti-inflammatory Role in Airway Disease.
Yin-Huai Chen, Charlotte E Cheadle, Louise V Rice, Paul E Pfeffer, Sarah Dimeloe

Front Nutr· August 2021

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Tolerogenic effects of 1,25-dihydroxyvitamin D on dendritic cells involve induction of fatty acid synthesis.
Amadeo Muñoz Garcia, Emma L Bishop, Danyang Li, Louisa E Jeffery, Antje Garten, Sarah Dimeloe

J Steroid Biochem Mol Biol· July 2021

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A glutamine 'tug-of-war': targets to manipulate glutamine metabolism for cancer immunotherapy.
Laura J Pallett, Sarah Dimeloe, Linda V Sinclair, Adam J Byrne, Anna Schurich

Immunother Adv· January 2021

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Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells.
Martin Kolev, Erin E West, Natalia Kunz, Daniel Chauss, E Ashley Moseman, Sarah Dimeloe

Immunity· March 2020

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SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2.
Anne-Valérie Burgener, Glenn R Bantug, Benedikt J Meyer, Rebecca Higgins, Adhideb Ghosh, Sarah Dimeloe

Nat Immunol· October 2019

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Intrinsic and Extrinsic Determinants of T Cell Metabolism in Health and Disease.
Haydn Munford, Sarah Dimeloe

Front Mol Biosci· October 2019

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Tumor-derived TGF-β inhibits mitochondrial respiration to suppress IFN-γ production by human CD4 T cells.
Sarah Dimeloe, Patrick Gubser, Jordan Loeliger, Corina Frick, Leyla Develioglu

Sci Signal· September 2019

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