Publications by authors named "Shim Jung-Hyun"

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CHI3L1 promotes cell division through activation of RhoA in lung cancer cells.
Ji Eun Yu, Jung-Hyun Shim, In Jun Yeo, Dong Ju Son, Jaesuk Yun

Cell Commun Signal· December 2025

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Modulating the BI-1(TMBIM6)/AKT Signaling Pathway by Licochalcone D Treatment Inhibits Human Melanoma Cell Growth.
Sun-Young Hwang, Cheol-Jung Lee, Kwanhwan Wi, Young-Kwon Kim, Soo-Bin Nam, Jung-Hyun Shim

Phytother Res· November 2025

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Protective Effects of Protein Hydrolysate against Atropine-Induced Dry Eye Disease.
Da Hye Kim, EunJin Bang, Seon Yeong Ji, Hyun Hwangbo, Min Yeong Kim, Jung-Hyun Shim

J Microbiol Biotechnol· November 2025

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Licochalcone D reduces HO-induced SH-SY5Y cell neurotoxicity by regulating reactive oxygen species.
Ah-Won Kwak, Seungmin Park, Ha-Na Oh, Jung-Hyun Shim, Goo Yoon

Front Pharmacol· October 2025

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RETRACTED: Kim et al. Protection against Oxidative Stress-Induced Apoptosis by Fermented Sea Tangle ( Aresch) in Osteoblastic MC3T3-E1 Cells through Activation of Nrf2 Signaling Pathway. 2021, , 2807.
So Young Kim, Hee-Jae Cha, Hyun Hwangbo, Cheol Park, Hyesook Lee, Jung-Hyun Shim

Foods· October 2025

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3-O-acetylrubiarbonol B preferentially targets EGFR and MET over rubiarbonol B to inhibit NSCLC cell growth.
A-Young Nam, Sang Hoon Joo, Na Yeong Lee, Goo Yoon, Jin Woo Park, Jung-Hyun Shim

PLoS One· September 2025

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Sulforaphane-Rich Broccoli Sprout Extract Promotes Hair Regrowth in an Androgenetic Alopecia Mouse Model via Enhanced Dihydrotestosterone Metabolism.
Laxman Subedi, Duc Dat Le, Eunbin Kim, Susmita Phuyal, Arjun Dhwoj Bamjan, Jung-Hyun Shim

Int J Mol Sci· August 2025

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Albiflorin, a Monoterpene Glycoside, Protects Myoblasts against Hydrogen Peroxide-Induced Apoptosis by Activating the Nrf2/HO-1 Axis.
Cheol Park, Hee-Jae Cha, Dong-Gu Kim, Su Hyun Hong, Sung-Kwon Moon, Jung-Hyun Shim

Biomol Ther (Seoul)· July 2025

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Oral Metronomic Delivery of Atorvastatin and Docetaxel via Transporter-Targeted Nanoemulsions Enhances Antitumor Efficacy and Immune Modulation in Colon Cancer.
Laxman Subedi, Arjun Dhwoj Bamjan, Susmita Phuyal, Bikram Khadka, Mansingh Chaudhary, Jung-Hyun Shim

Pharmaceutics· July 2025

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Cynaropicrin Induces Reactive Oxygen Species-Dependent Paraptosis-Like Cell Death in Human Liver Cancer Cells.
Min Yeong Kim, Hee-Jae Cha, Su Hyun Hong, Sung-Kwon Moon, Taeg Kyu Kwon, Jung-Hyun Shim

Biomol Ther (Seoul)· May 2025

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Paeoniflorin Protects Retinal Pigment Epithelial Cells from High Glucose-Induced Oxidative Damage by Activating Nrf2-Mediated HO-1 Signaling.
Cheol Park, Hee-Jae Cha, Su Hyun Hong, Jeong Sook Noh, Sang Hoon Hong, Jung-Hyun Shim

Biomol Ther (Seoul)· May 2025

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Anti-CHI3L1 antibody suppresses colon cancer growth through downregulation of VEGFA and NAMPT expression.
Ji Won Seo, Deok Rim Heo, Ji Eun Yu, A-Young Nam, Na Yeong Lee, Jung-Hyun Shim

Arch Pharm Res· May 2025

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Cynaropicrin induces the apoptosis of colorectal cancer cells by elevating reactive oxygen species and activating the JNK/p38 MAPK.
Si Yeong Seo, Sang Hoon Joo, Seung-On Lee, Ki-Taek Kim, Yung Hyun Choi, Jung-Hyun Shim

Am J Cancer Res· May 2025

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Isoalantolactone induces the apoptosis of oxaliplatin-resistant human colorectal cancer cells mediated by ROS generation and activation of JNK and p38 MAPK.
Seung-On Lee, Sang Hoon Joo, Na Yeong Lee, Seung-Sik Cho, Goo Yoon, Jung-Hyun Shim

Sci Rep· April 2025

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Cytotoxic activity of C polyacetylenes from the roots of Glehnia littoralis against drug-resistant colorectal and lung cancer cells.
Jisu Park, Sihyun Jang, Seung-On Lee, InWha Park, Sainan Li, Jung-Hyun Shim

J Nat Med· March 2025

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Licochalcone D Exerts Antitumor Activity in Human Colorectal Cancer Cells by Inducing ROS Generation and Phosphorylating JNK and p38 MAPK.
Seung-On Lee, Sang Hoon Joo, Seung-Sik Cho, Goo Yoon, Yung Hyun Choi, Jung-Hyun Shim

Biomol Ther (Seoul)· March 2025

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An oral liraglutide nanomicelle formulation conferring reduced insulin-resistance and long-term hypoglycemic and lipid metabolic benefits.
Laxman Subedi, Arjun Dhwoj Bamjan, Susmita Phuyal, Jung-Hyun Shim, Seung-Sik Cho

J Control Release· February 2025

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Deoxybouvardin Glucoside Induces Apoptosis in Oxaliplatin-Sensitive and -Resistant Colorectal Cancer Cells via Reactive Oxygen Species-Mediated Activation of JNK and p38 MAPK.
Seung-On Lee, Sang Hoon Joo, Jisu Park, Quan T Khong, Si Yeong Seo, Jung-Hyun Shim

J Microbiol Biotechnol· January 2025

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IL-32γ Induced Autophagy Through Suppression of MET and mTOR Pathways in Liver Tumor Growth Inhibition.
Ji-Won Seo, Yong-Sun Lee, In-Sook Jeon, Ji-Eun Yu, Jun-Sang Yoo, Jung-Hyun Shim

Int J Mol Sci· October 2024

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Deoxybouvardin-glucoside induces apoptosis in non-small cell lung cancer cells by targeting EGFR/MET and AKT signaling pathway.
Na Yeong Lee, Sang Hoon Joo, A-Young Nam, Seung-On Lee, Goo Yoon, Jung-Hyun Shim

EXCLI J· October 2024

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Deoxybouvardin targets EGFR, MET, and AKT signaling to suppress non-small cell lung cancer cells.
A-Young Nam, Sang Hoon Joo, Quan T Khong, Jisu Park, Na Yeong Lee, Jung-Hyun Shim

Sci Rep· September 2024

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Activation of p38 and JNK by ROS Contributes to Deoxybouvardin-Mediated Intrinsic Apoptosis in Oxaliplatin-Sensitive and -Resistant Colorectal Cancer Cells.
Si Yeong Seo, Sang Hoon Joo, Seung-On Lee, Goo Yoon, Seung-Sik Cho, Jung-Hyun Shim

Antioxidants (Basel)· July 2024

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Ameliorative effects of Linn. flower against desiccation stress-induced dry eye symptoms in the mice model.
Hyesook Lee, Hyun Hwangbo, Jin-Won Hyun, Jung-Hyun Shim, Sun-Hee Leem

Integr Med Res· June 2024

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Activation of Heme Oxygenase-1 by Mangiferin in Human Retinal Pigment Epithelial Cells Contributes to Blocking Oxidative Damage.
Cheol Park, Hee-Jae Cha, Hyun Hwangbo, EunJin Bang, Heui-Soo Kim, Jung-Hyun Shim

Biomol Ther (Seoul)· May 2024

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Coordinated ASBT and EGFR Mechanisms for Optimized Liraglutide Nanoformulation Absorption in the GI Tract.
Seho Kweon, Seong Jin Park, Ha Kyeong Lee, Seo Hee Kang, Kwan-Young Chang, Jung-Hyun Shim

Int J Nanomedicine· March 2024

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