Publications by authors named "ShuYan Du"

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Chemoproteomics-based profiling reveals the targeting molecular mechanism of reversal of cisplatin resistance by baicalin in head and neck squamous cell carcinoma.
Nan Wu, Shuang Yu, Shuyan Du, Xiaoqi Wei, Linyuan Wang

Biochem Pharmacol· December 2025

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ALK5 inhibitor impact on bleomycin-induced systemic sclerosis mouse model via multifunctional optical coherence tomography.
Pavel V Nikitin, Harshdeep S Chawla, Jessica Gutierrez, Geethangili Madamanchi, Manmohan Singh, Shuyan Du

APL Bioeng· December 2025

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Development, Characterization, and Radiation Dosimetry Studies of F-BMS-986229, a F-Labeled PD-L1 Macrocyclic Peptide PET Tracer.
Joonyoung Kim, David J Donnelly, Tritin Tran, Adrienne Pena, Andrea Olga Shorts, Shuyan Du

Mol Imaging Biol· April 2024

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The discovery and evaluation of [F]BMS-986229, a novel macrocyclic peptide PET radioligand for the measurement of PD-L1 expression and in-vivo PD-L1 target engagement.
David J Donnelly, Joonyoung Kim, Tritin Tran, Paul M Scola, Daniel Tenney, Shuyan Du

Eur J Nucl Med Mol Imaging· March 2024

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Is atrial fibrillation in HFpEF a distinct phenotype? Insights from multiparametric MRI and circulating biomarkers.
Abhishek Dattani, Emer M Brady, Prathap Kanagala, Svetlana Stoma, Kelly S Parke, Shuyan Du

BMC Cardiovasc Disord· February 2024

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Pegbelfermin in Patients With Nonalcoholic Steatohepatitis and Stage 3 Fibrosis (FALCON 1): A Randomized Phase 2b Study.
Rohit Loomba, Arun J Sanyal, Atsushi Nakajima, Brent A Neuschwander-Tetri, Zachary D Goodman, Arkendu Chatterjee, Shuyan Du

Clin Gastroenterol Hepatol· January 2024

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Pegbelfermin in Patients With Nonalcoholic Steatohepatitis and Compensated Cirrhosis (FALCON 2): A Randomized Phase 2b Study.
Manal F Abdelmalek, Arun J Sanyal, Atsushi Nakajima, Brent A Neuschwander-Tetri, Zachary D Goodman, Arkendu Chatterjee, Shuyan Du

Clin Gastroenterol Hepatol· January 2024

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Yes-Associated Protein 1 Inhibition Induces Immunogenic Cell Death and Synergizes With Radiation and PD-1 Blockade.
Yuan Zhuang, Yuzi Wang, Chang Liu, Sihan Li, Shuyan Du

Int J Radiat Oncol Biol Phys· July 2023

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Evaluation of BMS-986142, a reversible Bruton's tyrosine kinase inhibitor, for the treatment of rheumatoid arthritis: a phase 2, randomised, double-blind, dose-ranging, placebo-controlled, adaptive design study.
Philip G Conaghan, Miroslawa Nowak, Shuyan Du, Yi Luo, Jessica Landis

Lancet Rheumatol· May 2023

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Effect of pegbelfermin on NASH and fibrosis-related biomarkers and correlation with histological response in the FALCON 1 trial.
Elizabeth A Brown, Anne Minnich, Arun J Sanyal, Rohit Loomba, Shuyan Du

JHEP Rep· April 2023

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Implementation of the OMERACT Psoriatic Arthritis Magnetic Resonance Imaging Scoring System in a randomized phase IIb study of abatacept in psoriatic arthritis.
Mikkel Østergaard, Paul Bird, Chahin Pachai, Shuyan Du, Chun Wu

Rheumatology (Oxford)· November 2022

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Evaluation of a PEGylated Fibroblast Growth Factor 21 Variant Using Novel Preclinical Magnetic Resonance Imaging and Magnetic Resonance Elastography in a Mouse Model of Nonalcoholic Steatohepatitis.
Haiying Tang, Jiahui Li, Bradley Zinker, Stephanie Boehm, Amy Mauer, Shuyan Du

J Magn Reson Imaging· September 2022

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Excessive Activation of Notch Signaling in Macrophages Promote Kidney Inflammation, Fibrosis, and Necroptosis.
Tiankui Ma, Xin Li, Yonghong Zhu, Shufan Yu, Tianyan Liu, Shuyan Du

Front Immunol· May 2022

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BMS-986263 in patients with advanced hepatic fibrosis: 36-week results from a randomized, placebo-controlled phase 2 trial.
Eric J Lawitz, Diane E Shevell, Giridhar S Tirucherai, Shuyan Du, Warner Chen

Hepatology· April 2022

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LPA antagonist BMS-986020 changes collagen dynamics and exerts antifibrotic effects in vitro and in patients with idiopathic pulmonary fibrosis.
Benjamin E Decato, Diana Julie Leeming, Jannie Marie Bülow Sand, Aryeh Fischer, Shuyan Du

Respir Res· March 2022

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The value of imaging and clinical outcomes in a phase II clinical trial of a lysophosphatidic acid receptor antagonist in idiopathic pulmonary fibrosis.
Grace Hyun J Kim, Jonathan G Goldin, Wendy Hayes, Andrea Oh, Benjamin Soule, Shuyan Du

Ther Adv Respir Dis· November 2021

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The FALCON program: Two phase 2b randomized, double-blind, placebo-controlled studies to assess the efficacy and safety of pegbelfermin in the treatment of patients with nonalcoholic steatohepatitis and bridging fibrosis or compensated cirrhosis.
Manal F Abdelmalek, Edgar D Charles, Arun J Sanyal, Stephen A Harrison, Brent A Neuschwander-Tetri, Shuyan Du

Contemp Clin Trials· May 2021

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Identification of Non-Small Cell Lung Cancer Sensitive to Systemic Cancer Therapies Using Radiomics.
Laurent Dercle, Matthew Fronheiser, Lin Lu, Shuyan Du, Wendy Hayes

Clin Cancer Res· May 2020

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Zinc supplementation inhibits the high glucose‑induced EMT of peritoneal mesothelial cells by activating the Nrf2 antioxidant pathway.
Lili Gao, Yi Fan, Xiuli Zhang, Lina Yang, Wenyu Huang, Shuyan Du

Mol Med Rep· July 2019

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Selective production of phase-separable product from a mixture of biomass-derived aqueous oxygenates.
Yehong Wang, Mi Peng, Jian Zhang, Zhixin Zhang, Jinghua An, Shuyan Du

Nat Commun· December 2018

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Upregulation of miR-335 ameliorates myocardial ischemia reperfusion injury via targeting hypoxia inducible factor 1-alpha subunit inhibitor.
Nan Wu, Xiaowen Zhang, Shuyan Du, Dong Chen, Ruichao Che

Am J Transl Res· December 2018

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Evaluation of the Lysophosphatidic Acid Receptor Type 1 Radioligand C-BMT-136088 for Lung Imaging in Rhesus Monkeys.
Jean-Dominique Gallezot, Nabeel B Nabulsi, Daniel Holden, Shu-Fei Lin, David Labaree, Shuyan Du

J Nucl Med· February 2018

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Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease.
Viktor Martyanov, Grace-Hyun J Kim, Wendy Hayes, Shuyan Du, Bishu J Ganguly

PLoS One· November 2017

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Beneficial and Adverse Effects of an LXR Agonist on Human Lipid and Lipoprotein Metabolism and Circulating Neutrophils.
Todd G Kirchgessner, Paul Sleph, Jacek Ostrowski, John Lupisella, Carol S Ryan, Shuyan Du

Cell Metab· August 2016

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1,25(OH)2D3 inhibits high glucose-induced apoptosis and ROS production in human peritoneal mesothelial cells via the MAPK/P38 pathway.
Lina Yang, Lan Wu, Shuyan Du, Ye Hu, Yi Fan

Mol Med Rep· July 2016

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