Publications by authors named "Silke John"

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S
SIX of one and half-a-dozen USP2 regulating inflammation.
Lin Liu, John Silke

Cell Res· October 2025

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Enabling high-resolution diagnostic oral confocal laser endomicroscopy in mice.
Antonio Celentano, James A Rickard, Jun Low, Natasha Silke, Ali Ibrahim Mohammed, John Silke

Methods· July 2025

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The RBR E3 ubiquitin ligase HOIL-1 can ubiquitinate diverse non-protein substrates in vitro.
Xiangyi S Wang, Jenny Jiou, Anthony Cerra, Simon A Cobbold, Marco Jochem, John Silke

Life Sci Alliance· June 2025

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AXIN2 is a non-redundant regulator of AXIN1 stability and β-catenin in colorectal cancer cells.
Lin Liu, John Silke

FEBS J· March 2025

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Convolutional neural networks for accurate real-time diagnosis of oral epithelial dysplasia and oral squamous cell carcinoma using high-resolution in vivo confocal microscopy.
Rishi S Ramani, Ivy Tan, Lindsay Bussau, Lorraine A O'Reilly, John Silke

Sci Rep· January 2025

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Intracellular zinc protects tumours from T cell-mediated cytotoxicity.
Emily J Lelliott, Jonathan Naddaf, Katherine Ganio, Jessica Michie, Shelly Wang, John Silke

Cell Death Differ· December 2024

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Correction to: RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development.
Holly Anderton, Esther Bandala-Sanchez, Daniel S Simpson, James A Rickard, Ashley P Ng, John Silke

Cell Death Differ· December 2024

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Spatial proteomics identifies JAKi as treatment for a lethal skin disease.
Thierry M Nordmann, Holly Anderton, Akito Hasegawa, Lisa Schweizer, Peng Zhang, John Silke

Nature· November 2024

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Complex IIa formation and ABC transporters determine sensitivity of OSCC to Smac mimetics.
Yuhan Wang, Zijian Liu, Qian Si, Wanqiu Lu, Yuxian Song, John Silke

Cell Death Dis· November 2024

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An immunohistochemical atlas of necroptotic pathway expression.
Shene Chiou, Aysha H Al-Ani, Yi Pan, Komal M Patel, Isabella Y Kong, John Silke

EMBO Mol Med· July 2024

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Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity.
Pascal Meier, Arnaud J Legrand, Dieter Adam, John Silke

Nat Rev Cancer· May 2024

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RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation.
Hong Tri Tran, Tobias Kratina, Auriane Coutansais, Dominika Michalek, Benjamin M Hogan, John Silke

Cell Death Differ· May 2024

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Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency.
Hirotsugu Oda, Kalpana Manthiram, Pallavi Pimpale Chavan, Eva Rieser, Önay Veli, John Silke

Nat Immunol· May 2024

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RIPK1 and necroptosis role in premature ageing.
Panxue Wang, John Silke

Nat Cell Biol· April 2024

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Blocking cell death limits lung damage and inflammation from influenza.
Nishma Gupta, John Silke

Nature· April 2024

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Mind bomb 2 limits inflammatory dermatitis in mutant mice independently of cell death.
Daniel S Simpson, Holly Anderton, Jumana Yousef, Vineet Vaibhav, Simon A Cobbold, John Silke

PNAS Nexus· January 2024

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cIAPs control RIPK1 kinase activity-dependent and -independent cell death and tissue inflammation.
Fabian Schorn, J Paul Werthenbach, Mattes Hoffmann, Mila Daoud, Johanna Stachelscheid, John Silke

EMBO J· November 2023

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A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation.
Sarah E Garnish, Katherine R Martin, Maria Kauppi, Victoria E Jackson, Rebecca Ambrose, John Silke

Nat Commun· September 2023

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High molecular weight hyaluronic acid drastically reduces chemotherapy-induced mucositis and apoptotic cell death.
Ali I Mohammed, Antonio Celentano, Rita Paolini, Jun T Low, John Silke

Cell Death Dis· July 2023

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Apoptotic cell death in disease-Current understanding of the NCCD 2023.
Ilio Vitale, Federico Pietrocola, Emma Guilbaud, Stuart A Aaronson, John M Abrams, John A Cidlowski, John W Elrod, John J Lemasters, John Silke

Cell Death Differ· May 2023

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The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinase.
Catia L Pierotti, Annette V Jacobsen, Christoph Grohmann, Ruby K Dempsey, Nima Etemadi, John Silke

Biochem J· May 2023

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MLKL deficiency protects against low-grade, sterile inflammation in aged mice.
Emma C Tovey Crutchfield, Sarah E Garnish, Jessica Day, Holly Anderton, Shene Chiou, John Silke

Cell Death Differ· April 2023

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Caspase-8-driven apoptotic and pyroptotic crosstalk causes cell death and IL-1β release in X-linked inhibitor of apoptosis (XIAP) deficiency.
Sebastian A Hughes, Meng Lin, Ashley Weir, Bing Huang, Liya Xiong, John Silke

EMBO J· March 2023

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Deletion of Gpatch2 does not alter Tnf expression in mice.
Destiny Dalseno, Holly Anderton, Andrew Kueh, Marco J Herold, John Silke

Cell Death Dis· March 2023

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The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family.
Xiangyi S Wang, Thomas R Cotton, Sarah J Trevelyan, Lachlan W Richardson, Wei Ting Lee, John Silke

Nat Commun· January 2023

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