Publications by authors named "Simone Moorlag"

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Deciphering cross-cohort metabolic signatures of immune responses and their implications for disease pathogenesis.
Jianbo Fu, Nienke van Unen, Andrei Sarlea, Nhan Nguyen, Martin Jaeger, Simone J C F M Moorlag

Mol Syst Biol· November 2025

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Interleukin-38 is a negative regulator of trained immunity-A retrospective multi-omics study.
Lisa U Teufel, Vasiliki Matzaraki, Lukas Folkman, Dennis M de Graaf, Rob Ter Horst, Simone J C F M Moorlag

iScience· November 2025

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The impact of interferon-γ pathway on trained immunity induction by vaccination with Bacille Calmette-Guérin.
Ekaterina Isachesku, Andrei Cismaru, Vasiliki Matzaraki, Simone J C F M Moorlag, Vera P Mourits

Sci Rep· October 2025

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Long-term effects of BCG vaccination on telomere length and telomerase activity.
Ozlem Bulut, Valerie A C M Koeken, Simone J C F M Moorlag, Charlotte J de Bree, Vera P Mourits

iScience· August 2025

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Long-term DNA methylation changes mediate heterologous cytokine responses after BCG vaccination.
Cancan Qi, Zhaoli Liu, Gizem Kilic, Andrei S Sarlea, Priya A Debisarun, Simone J C F M Moorlag

Genome Biol· July 2025

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Sex-specific DNA methylation associations with circulating urate levels and BCG-induced urate changes.
Zhaoli Liu, Tania O Crișan, Cancan Qi, Manoj Kumar Gupta, Xuan Liu, Simone J C F M Moorlag

Commun Med (Lond)· July 2025

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Long-term histone lactylation connects metabolic and epigenetic rewiring in innate immune memory.
Athanasios Ziogas, Boris Novakovic, Lorenzo Ventriglia, Noriko Galang, Kim A Tran, Simone J C F M Moorlag

Cell· May 2025

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Immune correlates of early clearance of Mycobacterium tuberculosis among tuberculosis household contacts in Indonesia.
Todia P Setiabudiawan, Lika Apriani, Ayesha J Verrall, Fitria Utami, Marion Schneider, Simone J C F M Moorlag

Nat Commun· January 2025

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The effect of BCG vaccination in the elderly on infectious and non-infectious immune-mediated diseases.
Elisabeth A Dulfer, Konstantin Föhse, Esther J M Taks, Simone J C F M Moorlag, Eva L Koekenbier

J Infect· December 2024

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Insights into the multifaceted role of interleukin-37 on human immune cell regulation.
Lisa U Teufel, Vasiliki Matzaraki, Lukas Folkman, Rob Ter Horst, Simone J C F M Moorlag

Clin Immunol· November 2024

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RORα negatively regulates BCG-induced trained immunity.
Gizem Kilic, Vasiliki Matzaraki, Ozlem Bulut, Ilayda Baydemir, Anaisa V Ferreira, Simone J C F M Moorlag

Cell Immunol· September 2024

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Sex-specific epigenetic signatures of circulating urate and its increase after BCG vaccination.
Zhaoli Liu, Tania O Crișan, Cancan Qi, Manoj Kumar Gupta, Xuan Liu, Simone J C F M Moorlag

Res Sq· July 2024

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Common and distinct metabolomic markers related to immune aging in Western European and East African populations.
Ozlem Bulut, Godfrey S Temba, Valerie A C M Koeken, Simone J C F M Moorlag, L Charlotte J de Bree

Mech Ageing Dev· April 2024

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Epigenetic, transcriptional, and functional characterization of myeloid cells in familial Mediterranean fever.
Rutger J Röring, Wenchao Li, Ruiqi Liu, Mariolina Bruno, Bowen Zhang, Simone J C F M Moorlag

iScience· April 2024

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BCG vaccination induces innate immune memory in γδ T cells in humans.
Tsz K Suen, Simone J C F M Moorlag, Wenchao Li, L Charlotte J de Bree, Valerie A C M Koeken

J Leukoc Biol· January 2024

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A chromatin-regulated biphasic circuit coordinates IL-1β-mediated inflammation.
Ezio T Fok, Simone J C F M Moorlag, Yutaka Negishi, Laszlo A Groh, Jéssica Cristina Dos Santos

Nat Genet· January 2024

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11-deoxycortisol positively correlates with T cell immune traits in physiological conditions.
Chunying Peng, Xun Jiang, Martin Jaeger, Pepijn van Houten, Antonius E van Herwaarden, Simone J C F M Moorlag

EBioMedicine· January 2024

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BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination.
Krista E van Meijgaarden, Wenchao Li, Simone J C F M Moorlag, Valerie A C M Koeken, Hans J P M Koenen

Nat Commun· January 2024

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Multi-omics analysis of innate and adaptive responses to BCG vaccination reveals epigenetic cell states that predict trained immunity.
Simone J C F M Moorlag, Lukas Folkman, Rob Ter Horst, Thomas Krausgruber, Daniele Barreca

Immunity· January 2024

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Peripheral T Cell Populations are Differentially Affected in Familial Mediterranean Fever, Chronic Granulomatous Disease, and Gout.
Burcu Al, Mariolina Bruno, Rutger J Röring, Simone J C F M Moorlag, Tsz Kin Suen

J Clin Immunol· November 2023

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The impact of Bacillus Calmette-Guérin vaccination on antibody response after COVID-19 vaccination.
Esther J M Taks, Simone J C F M Moorlag, Konstantin Föhse, Elles Simonetti, Christa E van der Gaast-de Jongh

iScience· November 2023

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Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells.
David P Schrijver, Rutger J Röring, Jeroen Deckers, Anne de Dreu, Yohana C Toner, Simone J C F M Moorlag

Nat Biomed Eng· September 2023

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Targeting the 16S rRNA Gene by Reverse Complement PCR Next-Generation Sequencing: Specific and Sensitive Detection and Identification of Microbes Directly in Clinical Samples.
Simone J C F M Moorlag, Jordy P M Coolen, Bart van den Bosch, Elisabeth Hui-Mei Jin, Jochem B Buil

Microbiol Spectr· June 2023

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Dimethyl itaconate induces long-term innate immune responses and confers protection against infection.
Anaísa V Ferreira, Sarantos Kostidis, Laszlo A Groh, Valerie A C M Koeken, Mariolina Bruno, Simone J C F M Moorlag

Cell Rep· June 2023

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Corrigendum: The impact of circadian rhythm on Bacillus Calmette-Guérin vaccination effects on SARS-CoV-2 infections.
Konstantin Föhse, Esther J M Taks, Simone J C F M Moorlag, Marc J M Bonten, Reinout van Crevel

Front Immunol· May 2023

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