Publications by authors named "Stefan Freund"

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Phosphorylation-dependent tuning of mRNA deadenylation rates.
James A W Stowell, Conny W H Yu, Zhuo A Chen, Lily K DeBell, Giselle Lee, Stefan M V Freund

Nat Struct Mol Biol· November 2025

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Molecular mechanism of Mad2 conformational conversion promoted by the Mad2-interaction motif of Cdc20.
Conny W H Yu, Elyse S Fischer, Joe G Greener, Jing Yang, Ziguo Zhang, Stefan M V Freund

Protein Sci· April 2025

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ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.
Jonathon Nixon-Abell, Francesco S Ruggeri, Seema Qamar, Therese W Herling, Magdalena A Czekalska, Stefan M V Freund

Nat Commun· March 2025

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Recruitment of trimeric eIF2 by phosphatase non-catalytic subunit PPP1R15B.
Agnieszka Fatalska, George Hodgson, Stefan M V Freund, Sarah L Maslen, Tomos Morgan

Mol Cell· February 2024

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Disease-specific tau filaments assemble via polymorphic intermediates.
Sofia Lövestam, David Li, Jane L Wagstaff, Abhay Kotecha, Dari Kimanius, Stefan M V Freund

Nature· January 2024

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Dynamic conformational changes of a tardigrade group-3 late embryogenesis abundant protein modulate membrane biophysical properties.
Xiao-Han Li, Conny W H Yu, Natalia Gomez-Navarro, Viktoriya Stancheva, Hongni Zhu, Stefan M V Freund

PNAS Nexus· January 2024

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ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.
Jonathon Nixon-Abell, Francesco S Ruggeri, Seema Qamar, Therese W Herling, Magdalena A Czekalska, Stefan M V Freund

bioRxiv· March 2023

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Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN.
Tim Nierhaus, Stephen H McLaughlin, Frank Bürmann, Danguole Kureisaite-Ciziene, Sarah L Maslen, Stefan M V Freund

Nat Microbiol· October 2022

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Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly.
Elyse S Fischer, Conny W H Yu, Johannes F Hevler, Stephen H McLaughlin, Sarah L Maslen, Stefan M V Freund

Nat Commun· October 2022

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Dynamics in Fip1 regulate eukaryotic mRNA 3' end processing.
Ananthanarayanan Kumar, Conny W H Yu, Juan B Rodríguez-Molina, Xiao-Han Li, Stefan M V Freund

Genes Dev· November 2021

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Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains.
Paul R Elliott, Derek Leske, Jane Wagstaff, Lisa Schlicher, Georgina Berridge, Stefan M V Freund

Cell Rep· October 2021

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Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace.
Maren Heimhalt, Alex Berndt, Jane Wagstaff, Madhanagopal Anandapadamanaban, Olga Perisic, Stefan M Freund

Elife· September 2021

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Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Elyse S Fischer, Conny W H Yu, Dom Bellini, Stephen H McLaughlin, Christian M Orr, Stefan M V Freund

EMBO Rep· July 2021

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Regulation of Dishevelled DEP domain swapping by conserved phosphorylation sites.
Gonzalo J Beitia, Trevor J Rutherford, Stefan M V Freund, Hugh R Pelham, Mariann Bienz

Proc Natl Acad Sci U S A· June 2021

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Controlled Ligand Exchange Between Ruthenium Organometallic Cofactor Precursors and a Naïve Protein Scaffold Generates Artificial Metalloenzymes Catalysing Transfer Hydrogenation.
George S Biggs, Oskar James Klein, Sarah L Maslen, J Mark Skehel, Trevor J Rutherford, Stefan M V Freund

Angew Chem Int Ed Engl· May 2021

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SWI/SNF subunit BAF155 N-terminus structure informs the impact of cancer-associated mutations and reveals a potential drug binding site.
Mark D Allen, Stefan M V Freund, Mark Bycroft, Giovanna Zinzalla

Commun Biol· May 2021

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The native structure of the assembled matrix protein 1 of influenza A virus.
Julia Peukes, Xiaoli Xiong, Simon Erlendsson, Kun Qu, William Wan, Stefan M V Freund

Nature· November 2020

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Periphilin self-association underpins epigenetic silencing by the HUSH complex.
Daniil M Prigozhin, Christopher H Douse, Laura E Farleigh, Anna Albecka, Iva A Tchasovnikarova, Stefan M V Freund

Nucleic Acids Res· October 2020

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TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control.
Christopher H Douse, Iva A Tchasovnikarova, Richard T Timms, Anna V Protasio, Marta Seczynska, Stefan M V Freund

Nat Commun· October 2020

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CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Takashi Ochi, Valentina Quarantotti, Huawen Lin, Jerome Jullien, Ivan Rosa E Silva, Stefan M V Freund

Structure· June 2020

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Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA.
Susan Sammak, Najoua Hamdani, Fabrice Gorrec, Mark D Allen, Stefan M V Freund

Biochemistry· July 2019

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Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.
Malte Gersch, Jane L Wagstaff, Angela V Toms, Bradford Graves, Stefan M V Freund

Mol Cell· May 2019

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Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Vasileios Kargas, Pablo Castro-Hartmann, Norberto Escudero-Urquijo, Kyle Dent, Christine Hilcenko, Stefan Mv Freund

Elife· May 2019

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Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis.
Nimesh Joseph, Caezar Al-Jassar, Christopher M Johnson, Antonina Andreeva, Deepak D Barnabas, Stefan M V Freund

Cell Rep· May 2018

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Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.
Yi Liu, Gagan D Gupta, Deepak D Barnabas, Fikret G Agircan, Shahid Mehmood, Stefan M V Freund

Nat Commun· April 2018

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